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Is Autologous Fecal Microbiota Transfer after Exclusive Enteral Nutrition in Pediatric Crohn's Disease Patients Rational and Feasible? Data from a Feasibility Test.
Hoelz H, Heetmeyer J, Tsakmaklis A, Hiergeist A, Siebert K, De Zen F, Häcker D, Metwaly A, Neuhaus K, Gessner A, Vehreschild MJGT, Haller D, Schwerd T. Hoelz H, et al. Among authors: schwerd t. Nutrients. 2023 Apr 2;15(7):1742. doi: 10.3390/nu15071742. Nutrients. 2023. PMID: 37049583 Free PMC article.
5'-Triphosphate-siRNA: turning gene silencing and Rig-I activation against melanoma.
Poeck H, Besch R, Maihoefer C, Renn M, Tormo D, Morskaya SS, Kirschnek S, Gaffal E, Landsberg J, Hellmuth J, Schmidt A, Anz D, Bscheider M, Schwerd T, Berking C, Bourquin C, Kalinke U, Kremmer E, Kato H, Akira S, Meyers R, Häcker G, Neuenhahn M, Busch D, Ruland J, Rothenfusser S, Prinz M, Hornung V, Endres S, Tüting T, Hartmann G. Poeck H, et al. Among authors: schwerd t. Nat Med. 2008 Nov;14(11):1256-63. doi: 10.1038/nm.1887. Epub 2008 Nov 2. Nat Med. 2008. PMID: 18978796
5'-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I.
Schmidt A, Schwerd T, Hamm W, Hellmuth JC, Cui S, Wenzel M, Hoffmann FS, Michallet MC, Besch R, Hopfner KP, Endres S, Rothenfusser S. Schmidt A, et al. Among authors: schwerd t. Proc Natl Acad Sci U S A. 2009 Jul 21;106(29):12067-72. doi: 10.1073/pnas.0900971106. Epub 2009 Jul 2. Proc Natl Acad Sci U S A. 2009. PMID: 19574455 Free PMC article.
Partial enteral nutrition has no benefit on bone health but improves growth in paediatric patients with quiescent or mild Crohn's disease.
Brückner A, Werkstetter KJ, Frivolt K, Shokry E, Ahmed M, Metwaly A, Marques JG, Uhl O, Krohn K, Hajji M, Otte S, Pozza SB, Bufler P, Liptay S, Haller D, Koletzko B, Koletzko S, Schwerd T. Brückner A, et al. Among authors: schwerd t. Clin Nutr. 2020 Dec;39(12):3786-3796. doi: 10.1016/j.clnu.2020.04.012. Epub 2020 Apr 22. Clin Nutr. 2020. PMID: 32376096 Clinical Trial.
Diet prevents the expansion of segmented filamentous bacteria and ileo-colonic inflammation in a model of Crohn's disease.
Metwaly A, Jovic J, Waldschmitt N, Khaloian S, Heimes H, Häcker D, Ahmed M, Hammoudi N, Le Bourhis L, Mayorgas A, Siebert K, Basic M, Schwerd T, Allez M, Panes J, Salas A, Bleich A, Zeissig S, Schnupf P, Cominelli F, Haller D. Metwaly A, et al. Among authors: schwerd t. Microbiome. 2023 Mar 31;11(1):66. doi: 10.1186/s40168-023-01508-y. Microbiome. 2023. PMID: 37004103 Free PMC article.
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