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HIF-1: using two hands to flip the angiogenic switch.
Semenza GL. Semenza GL. Cancer Metastasis Rev. 2000;19(1-2):59-65. doi: 10.1023/a:1026544214667. Cancer Metastasis Rev. 2000. PMID: 11191064 Review.
Signal transduction to hypoxia-inducible factor 1.
Semenza G. Semenza G. Biochem Pharmacol. 2002 Sep;64(5-6):993-8. doi: 10.1016/s0006-2952(02)01168-1. Biochem Pharmacol. 2002. PMID: 12213597 Review.
Differential regulation of vascular endothelial growth factor during ventilated pulmonary ischemia.
Yu A, Alcasabas A, Semenza G, Becker P. Yu A, et al. Among authors: semenza g. Chest. 1999 Jul;116(1 Suppl):32S. doi: 10.1378/chest.116.suppl_1.32s. Chest. 1999. PMID: 10424577 No abstract available.
HIF-1α is required for development of the sympathetic nervous system.
Bohuslavova R, Cerychova R, Papousek F, Olejnickova V, Bartos M, Görlach A, Kolar F, Sedmera D, Semenza GL, Pavlinkova G. Bohuslavova R, et al. Among authors: semenza gl. Proc Natl Acad Sci U S A. 2019 Jul 2;116(27):13414-13423. doi: 10.1073/pnas.1903510116. Epub 2019 Jun 13. Proc Natl Acad Sci U S A. 2019. PMID: 31196952 Free PMC article.
Hypoxia-inducible factor 1 and cardiovascular disease.
Semenza GL. Semenza GL. Annu Rev Physiol. 2014;76:39-56. doi: 10.1146/annurev-physiol-021113-170322. Epub 2013 Aug 21. Annu Rev Physiol. 2014. PMID: 23988176 Free PMC article. Review.
Hypoxia-inducible factor-dependent breast cancer-mesenchymal stem cell bidirectional signaling promotes metastasis.
Chaturvedi P, Gilkes DM, Wong CC; Kshitiz, Luo W, Zhang H, Wei H, Takano N, Schito L, Levchenko A, Semenza GL. Chaturvedi P, et al. Among authors: semenza gl. J Clin Invest. 2013 Jan;123(1):189-205. doi: 10.1172/JCI64993. Epub 2012 Dec 17. J Clin Invest. 2013. PMID: 23318994 Free PMC article.
Tie2-dependent knockout of HIF-1 impairs burn wound vascularization and homing of bone marrow-derived angiogenic cells.
Sarkar K, Rey S, Zhang X, Sebastian R, Marti GP, Fox-Talbot K, Cardona AV, Du J, Tan YS, Liu L, Lay F, Gonzalez FJ, Harmon JW, Semenza GL. Sarkar K, et al. Among authors: semenza gl. Cardiovasc Res. 2012 Jan 1;93(1):162-9. doi: 10.1093/cvr/cvr282. Epub 2011 Oct 25. Cardiovasc Res. 2012. PMID: 22028336 Free PMC article.
Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment.
Chaturvedi P, Gilkes DM, Takano N, Semenza GL. Chaturvedi P, et al. Among authors: semenza gl. Proc Natl Acad Sci U S A. 2014 May 20;111(20):E2120-9. doi: 10.1073/pnas.1406655111. Epub 2014 May 5. Proc Natl Acad Sci U S A. 2014. PMID: 24799675 Free PMC article.
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression.
Luo W, Chang R, Zhong J, Pandey A, Semenza GL. Luo W, et al. Among authors: semenza gl. Proc Natl Acad Sci U S A. 2012 Dec 4;109(49):E3367-76. doi: 10.1073/pnas.1217394109. Epub 2012 Nov 5. Proc Natl Acad Sci U S A. 2012. PMID: 23129632 Free PMC article.
Oxygen homeostasis.
Semenza GL. Semenza GL. Wiley Interdiscip Rev Syst Biol Med. 2010 May-Jun;2(3):336-361. doi: 10.1002/wsbm.69. Wiley Interdiscip Rev Syst Biol Med. 2010. PMID: 20836033 Review.
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