Soos MA - Search Results

1

Congenital leptin deficiency is associated with severe early-onset obesity in humans.

Montague CT, Farooqi IS, Whitehead JP, Soos MA, Rau H, Wareham NJ, Sewter CP, Digby JE, Mohammed SN, Hurst JA, Cheetham CH, Earley AR, Barnett AH, Prins JB, O'Rahilly S. Montague CT, et al. Among authors: soos ma. Nature. 1997 Jun 26;387(6636):903-8. doi: 10.1038/43185. Nature. 1997. PMID: 9202122

2

Digenic inheritance of severe insulin resistance in a human pedigree.

Savage DB, Agostini M, Barroso I, Gurnell M, Luan J, Meirhaeghe A, Harding AH, Ihrke G, Rajanayagam O, Soos MA, George S, Berger D, Thomas EL, Bell JD, Meeran K, Ross RJ, Vidal-Puig A, Wareham NJ, O'Rahilly S, Chatterjee VK, Schafer AJ. Savage DB, et al. Among authors: soos ma. Nat Genet. 2002 Aug;31(4):379-84. doi: 10.1038/ng926. Epub 2002 Jul 15. Nat Genet. 2002. PMID: 12118251

3

Genetic variants of insulin receptor substrate-1 (IRS-1) in syndromes of severe insulin resistance. Functional analysis of Ala513Pro and Gly1158Glu IRS-1.

Berger D, Barroso I, Soos M, Yeo G, Schafer AJ, O'Rahilly S, Whitehead JP. Berger D, et al. Diabet Med. 2002 Oct;19(10):804-9. doi: 10.1046/j.1464-5491.2002.00779.x. Diabet Med. 2002. PMID: 12358865

4

Dominant negative mutations in human PPARgamma associated with severe insulin resistance, diabetes mellitus and hypertension.

Barroso I, Gurnell M, Crowley VE, Agostini M, Schwabe JW, Soos MA, Maslen GL, Williams TD, Lewis H, Schafer AJ, Chatterjee VK, O'Rahilly S. Barroso I, et al. Among authors: soos ma. Nature. 1999 Dec 23-30;402(6764):880-3. doi: 10.1038/47254. Nature. 1999. PMID: 10622252

5

Elevated plasma adiponectin in humans with genetically defective insulin receptors.

Semple RK, Soos MA, Luan J, Mitchell CS, Wilson JC, Gurnell M, Cochran EK, Gorden P, Chatterjee VK, Wareham NJ, O'Rahilly S. Semple RK, et al. Among authors: soos ma. J Clin Endocrinol Metab. 2006 Aug;91(8):3219-23. doi: 10.1210/jc.2006-0166. Epub 2006 May 16. J Clin Endocrinol Metab. 2006. PMID: 16705075

6

Natural variants of human p85 alpha phosphoinositide 3-kinase in severe insulin resistance: a novel variant with impaired insulin-stimulated lipid kinase activity.

Baynes KC, Beeton CA, Panayotou G, Stein R, Soos M, Hansen T, Simpson H, O'Rahilly S, Shepherd PR, Whitehead JP. Baynes KC, et al. Diabetologia. 2000 Mar;43(3):321-31. doi: 10.1007/s001250050050. Diabetologia. 2000. PMID: 10768093

7

Functional activation of mutant human insulin receptor by monoclonal antibody.

Krook A, Soos MA, Kumar S, Siddle K, O'Rahilly S. Krook A, et al. Among authors: soos ma. Lancet. 1996 Jun 8;347(9015):1586-90. doi: 10.1016/s0140-6736(96)91076-4. Lancet. 1996. PMID: 8667867

8

Impaired activation of phosphoinositide 3-kinase by insulin in fibroblasts from patients with severe insulin resistance and pseudoacromegaly. A disorder characterized by selective postreceptor insulin resistance.

Dib K, Whitehead JP, Humphreys PJ, Soos MA, Baynes KC, Kumar S, Harvey T, O'Rahilly S. Dib K, et al. Among authors: soos ma. J Clin Invest. 1998 Mar 1;101(5):1111-20. doi: 10.1172/JCI119884. J Clin Invest. 1998. PMID: 9486982 Free PMC article.

9

Multiple molecular mechanisms of insulin receptor dysfunction in a patient with Donohue syndrome.

Whitehead JP, Soos MA, Jackson R, Tasic V, Kocova M, O'Rahilly S. Whitehead JP, et al. Among authors: soos ma. Diabetes. 1998 Aug;47(8):1362-4. doi: 10.2337/diab.47.8.1362. Diabetes. 1998. PMID: 9703342 No abstract available.

10

Differential signaling to glycogen synthesis by the intracellular domain of the insulin versus the insulin-like growth factor-1 receptor. Evidence from studies of TrkC-chimeras.

Kalloo-Hosein HE, Whitehead JP, Soos M, Tavaré JM, Siddle K, O'Rahilly S. Kalloo-Hosein HE, et al. J Biol Chem. 1997 Sep 26;272(39):24325-32. doi: 10.1074/jbc.272.39.24325. J Biol Chem. 1997. PMID: 9305889 Free article.

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