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SIRT3 regulates mitochondrial fatty-acid oxidation by reversible enzyme deacetylation.
Hirschey MD, Shimazu T, Goetzman E, Jing E, Schwer B, Lombard DB, Grueter CA, Harris C, Biddinger S, Ilkayeva OR, Stevens RD, Li Y, Saha AK, Ruderman NB, Bain JR, Newgard CB, Farese RV Jr, Alt FW, Kahn CR, Verdin E. Hirschey MD, et al. Among authors: stevens rd. Nature. 2010 Mar 4;464(7285):121-5. doi: 10.1038/nature08778. Nature. 2010. PMID: 20203611 Free PMC article.
Leptin therapy in insulin-deficient type I diabetes.
Wang MY, Chen L, Clark GO, Lee Y, Stevens RD, Ilkayeva OR, Wenner BR, Bain JR, Charron MJ, Newgard CB, Unger RH. Wang MY, et al. Among authors: stevens rd. Proc Natl Acad Sci U S A. 2010 Mar 16;107(11):4813-9. doi: 10.1073/pnas.0909422107. Epub 2010 Mar 1. Proc Natl Acad Sci U S A. 2010. PMID: 20194735 Free PMC article.
SIRT3 deficiency and mitochondrial protein hyperacetylation accelerate the development of the metabolic syndrome.
Hirschey MD, Shimazu T, Jing E, Grueter CA, Collins AM, Aouizerat B, Stančáková A, Goetzman E, Lam MM, Schwer B, Stevens RD, Muehlbauer MJ, Kakar S, Bass NM, Kuusisto J, Laakso M, Alt FW, Newgard CB, Farese RV Jr, Kahn CR, Verdin E. Hirschey MD, et al. Among authors: stevens rd. Mol Cell. 2011 Oct 21;44(2):177-90. doi: 10.1016/j.molcel.2011.07.019. Mol Cell. 2011. PMID: 21856199 Free PMC article.
Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine export.
White PJ, Lapworth AL, An J, Wang L, McGarrah RW, Stevens RD, Ilkayeva O, George T, Muehlbauer MJ, Bain JR, Trimmer JK, Brosnan MJ, Rolph TP, Newgard CB. White PJ, et al. Among authors: stevens rd. Mol Metab. 2016 Apr 22;5(7):538-551. doi: 10.1016/j.molmet.2016.04.006. eCollection 2016 Jul. Mol Metab. 2016. PMID: 27408778 Free PMC article.
Skeletal muscle Nur77 expression enhances oxidative metabolism and substrate utilization.
Chao LC, Wroblewski K, Ilkayeva OR, Stevens RD, Bain J, Meyer GA, Schenk S, Martinez L, Vergnes L, Narkar VA, Drew BG, Hong C, Boyadjian R, Hevener AL, Evans RM, Reue K, Spencer MJ, Newgard CB, Tontonoz P. Chao LC, et al. Among authors: stevens rd. J Lipid Res. 2012 Dec;53(12):2610-9. doi: 10.1194/jlr.M029355. Epub 2012 Oct 1. J Lipid Res. 2012. PMID: 23028113 Free PMC article.
365 results