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Balance between activating NKG2D, DNAM-1, NKp44 and NKp46 and inhibitory CD94/NKG2A receptors determine natural killer degranulation towards rheumatoid arthritis synovial fibroblasts.
Nielsen N, Pascal V, Fasth AE, Sundström Y, Galsgaard ED, Ahern D, Andersen M, Baslund B, Bartels EM, Bliddal H, Feldmann M, Malmström V, Berg L, Spee P, Söderström K. Nielsen N, et al. Among authors: sundstrom y. Immunology. 2014 Aug;142(4):581-93. doi: 10.1111/imm.12271. Immunology. 2014. PMID: 24673109 Free PMC article. Clinical Trial.
Integration of known DNA, RNA and protein biomarkers provides prediction of anti-TNF response in rheumatoid arthritis: results from the COMBINE study.
Folkersen L, Brynedal B, Diaz-Gallo LM, Ramsköld D, Shchetynsky K, Westerlind H, Sundström Y, Schepis D, Hensvold A, Vivar N, Eloranta ML, Rönnblom L, Brunak S, Malmström V, Catrina A, Moerch UG, Klareskog L, Padyukov L, Berg L. Folkersen L, et al. Among authors: sundstrom y. Mol Med. 2016 Sep;22:322-328. doi: 10.2119/molmed.2016.00078. Epub 2016 Aug 15. Mol Med. 2016. PMID: 27532898 Free PMC article.
A genetics-led approach defines the drug target landscape of 30 immune-related traits.
Fang H; ULTRA-DD Consortium; De Wolf H, Knezevic B, Burnham KL, Osgood J, Sanniti A, Lledó Lara A, Kasela S, De Cesco S, Wegner JK, Handunnetthi L, McCann FE, Chen L, Sekine T, Brennan PE, Marsden BD, Damerell D, O'Callaghan CA, Bountra C, Bowness P, Sundström Y, Milani L, Berg L, Göhlmann HW, Peeters PJ, Fairfax BP, Sundström M, Knight JC. Fang H, et al. Among authors: sundstrom y. Nat Genet. 2019 Jul;51(7):1082-1091. doi: 10.1038/s41588-019-0456-1. Epub 2019 Jun 28. Nat Genet. 2019. PMID: 31253980 Free PMC article.
16 results