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Year Number of Results
2009 2
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31 results

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Page 1
miRNA-Processing Gene Methylation and Cancer Risk.
Joyce BT, Zheng Y, Zhang Z, Liu L, Kocherginsky M, Murphy R, Achenbach CJ, Musa J, Wehbe F, Just A, Shen J, Vokonas P, Schwartz J, Baccarelli AA, Hou L. Joyce BT, et al. Cancer Epidemiol Biomarkers Prev. 2018 May;27(5):550-557. doi: 10.1158/1055-9965.EPI-17-0849. Epub 2018 Feb 23. Cancer Epidemiol Biomarkers Prev. 2018. PMID: 29475968 Free PMC article.

Associations at false discovery rate < 0.05 were considered statistically significant.Results: Methylation of three CpGs (DROSHA: cg23230564, TNRC6B: cg06751583, and TNRC6B: cg21034183) was prospectively associated with time to cancer development (positive

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Associations at false discovery rate < 0.05 were considered statistically significant.Results: Methylation of three CpGs (DROSHA: cg23230

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Circular RNA circ-TNRC6B inhibits the proliferation and invasion of esophageal squamous cell carcinoma cells by regulating the miR-452-5p/DAG1 axis.
Xu R, Ding P, Zhao X, Li Z, Liu F, Gu L, Zheng Y, Sang M, Meng L. Xu R, et al. Mol Oncol. 2023 Jul;17(7):1437-1452. doi: 10.1002/1878-0261.13432. Epub 2023 Apr 16. Mol Oncol. 2023. PMID: 37014625 Free PMC article.
This study characterized a newly identified circRNA derived from exons 9-13 of TNRC6B (named circ-TNRC6B). The expression of circ-TNRC6B in ESCC tissues was markedly downregulated when compared to that in non-tumor tissues. ...Thus, circ-TNRC6B is a po …
This study characterized a newly identified circRNA derived from exons 9-13 of TNRC6B (named circ-TNRC6B). The expression of c …
FOXA1-induced LINC01207 facilitates head and neck squamous cell carcinoma via up-regulation of TNRC6B.
Chen C, Jiang L, Zhang Y, Zheng W. Chen C, et al. Biomed Pharmacother. 2020 Aug;128:110220. doi: 10.1016/j.biopha.2020.110220. Epub 2020 May 22. Biomed Pharmacother. 2020. PMID: 32450521 Free article.
Head and neck squamous cell carcinoma (HNSCC) is a common cancer in China, which was mainly caused by smoking and HPV infection. ...Then, we identified that transcription of both LINC01207 and TNRC6B was induced by FOXA1, which played a tumor facilitator role in HNS …
Head and neck squamous cell carcinoma (HNSCC) is a common cancer in China, which was mainly caused by smoking and HPV infection. ...T …
In silico analysis of prognostic and diagnostic significance of target genes from prostate cancer cell lines derived exomicroRNAs.
Altuna-Coy A, Ruiz-Plazas X, Arreaza-Gil V, Segarra-Tomás J, Chacón MR. Altuna-Coy A, et al. Cancer Cell Int. 2023 Nov 17;23(1):275. doi: 10.1186/s12935-023-03123-1. Cancer Cell Int. 2023. PMID: 37978493 Free PMC article.
BACKGROUND: Cancer-secreted exovesicles are important for cell-to-cell communication by altering cancer-related signalling pathways. ...Reactome pathway database revealed altered pathways and genes related to miRNA biosynthesis, miRNA-mediated gene silencing (TNR …
BACKGROUND: Cancer-secreted exovesicles are important for cell-to-cell communication by altering cancer-related signalling pat …
Circular RNA circABCC4 regulates lung adenocarcinoma progression via miR-3186-3p/TNRC6B axis.
Liu M, Wang P, Sui X, Ding F, Liu L, Gao Z, Cheng Z. Liu M, et al. J Cell Biochem. 2020 Oct;121(10):4226-4238. doi: 10.1002/jcb.29627. Epub 2020 Jan 21. J Cell Biochem. 2020. PMID: 31960988
Final rescue experiments further delineated that TNRC6B upregulation partially restored circABCC4 downregulation-mediated effect on LUAD progression. In sum, circABCC4 regulates LUAD progression via miR-3186-3p/TNRC6B axis....
Final rescue experiments further delineated that TNRC6B upregulation partially restored circABCC4 downregulation-mediated effect on L …
Association of BET1L and TNRC6B with uterine leiomyoma risk and its relevant clinical features in Han Chinese population.
Liu B, Wang T, Jiang J, Li M, Ma W, Wu H, Zhou Q. Liu B, et al. Sci Rep. 2018 May 9;8(1):7401. doi: 10.1038/s41598-018-25792-z. Sci Rep. 2018. PMID: 29743541 Free PMC article.
We aimed to replicate two initial significant genetic factors, TNRC6B and BET1L, in a Han Chinese population. A total of 2,055 study subjects were recruited, and 55 SNPs mapped to TNRC6B and BET1L were selected and genotyped in samples from these subjects. ...Both S …
We aimed to replicate two initial significant genetic factors, TNRC6B and BET1L, in a Han Chinese population. A total of 2,055 study …
BET1L and TNRC6B associate with uterine fibroid risk among European Americans.
Edwards TL, Michels KA, Hartmann KE, Velez Edwards DR. Edwards TL, et al. Hum Genet. 2013 Aug;132(8):943-53. doi: 10.1007/s00439-013-1306-3. Epub 2013 Apr 19. Hum Genet. 2013. PMID: 23604678 Free PMC article.
Two SNP associations replicated [blocked early in transport 1 homolog (BET1L) rs2280543, RFTS-BioVU meta-odds ratio (OR) = 0.67 95 % confidence interval (CI) 0.38-0.96, Q = 0.70, I = 0, p = 6.9 10-3; trinucleotide repeat containing 6B (TNRC6B) rs12484776, RFTS-BioVU meta-O …
Two SNP associations replicated [blocked early in transport 1 homolog (BET1L) rs2280543, RFTS-BioVU meta-odds ratio (OR) = 0.67 95 % confide …
Single-nucleotide polymorphisms of microRNA processing machinery genes are associated with risk for gastric cancer.
Xie Y, Wang Y, Zhao Y, Guo Z. Xie Y, et al. Onco Targets Ther. 2015 Mar 4;8:567-71. doi: 10.2147/OTT.S79150. eCollection 2015. Onco Targets Ther. 2015. PMID: 25784816 Free PMC article.
Recent studies demonstrate that microRNA-related single-nucleotide polymorphisms (miR-SNPs) are associated with the development of numerous human cancers. In this study, we investigated six miR-SNPs in microRNA processing machinery genes, including rs11077 of the XPO5 gene …
Recent studies demonstrate that microRNA-related single-nucleotide polymorphisms (miR-SNPs) are associated with the development of numerous …
TNRC6 proteins modulate hepatitis C virus replication by spatially regulating the binding of miR-122/Ago2 complexes to viral RNA.
Li Y, Wang L, Rivera-Serrano EE, Chen X, Lemon SM. Li Y, et al. Nucleic Acids Res. 2019 Jul 9;47(12):6411-6424. doi: 10.1093/nar/gkz278. Nucleic Acids Res. 2019. PMID: 30997501 Free PMC article.
TNRC6B/C were required for optimal miR-122 host factor activity only when S1 was able to bind miR-122, and restricted replication when S1 was mutated and only S2 bound by miR-122. TNRC6B/C preferentially associated with S1, and TNRC6B/C depletion enhanced Ago …
TNRC6B/C were required for optimal miR-122 host factor activity only when S1 was able to bind miR-122, and restricted replication whe …
Variants in BET1L and TNRC6B associate with increasing fibroid volume and fibroid type among European Americans.
Edwards TL, Hartmann KE, Velez Edwards DR. Edwards TL, et al. Hum Genet. 2013 Dec;132(12):1361-9. doi: 10.1007/s00439-013-1340-1. Epub 2013 Jul 28. Hum Genet. 2013. PMID: 23892540 Free PMC article.
We also combined association results of UF type using meta-analysis. 456 European American (EA) cases and 1,549 controls were examined. Trinucleotide repeat containing 6B (TNRC6B) rs12484776 associated with volume in RFTS (beta = 0.40, 95 % CI 0.05-0.75, p = 0.024). ...
We also combined association results of UF type using meta-analysis. 456 European American (EA) cases and 1,549 controls were examined. Trin …
31 results