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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1955 1
1956 1
1960 1
1964 2
1967 2
1970 1
1971 2
1972 3
1973 2
1975 20
1976 20
1977 24
1978 20
1979 34
1980 33
1981 24
1982 24
1983 40
1984 36
1985 34
1986 31
1987 26
1988 42
1989 57
1990 55
1991 65
1992 60
1993 76
1994 56
1995 57
1996 83
1997 80
1998 115
1999 127
2000 145
2001 180
2002 181
2003 225
2004 274
2005 298
2006 317
2007 355
2008 380
2009 419
2010 439
2011 454
2012 479
2013 574
2014 506
2015 495
2016 503
2017 497
2018 501
2019 491
2020 540
2021 606
2022 608
2023 550
2024 201

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10,209 results

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Page 1
Clinical and laboratory diagnosis of TTP: an integrated approach.
Chiasakul T, Cuker A. Chiasakul T, et al. Hematology Am Soc Hematol Educ Program. 2018 Nov 30;2018(1):530-538. doi: 10.1182/asheducation-2018.1.530. Hematology Am Soc Hematol Educ Program. 2018. PMID: 30504354 Free PMC article. Review.
In such instances, initial management decisions must be made without the benefit of laboratory testing. In patients with TTP, inhibitor tests may be useful for distinguishing immune-mediated from congenital TTP. In this article, we review the epidemiology, natural h …
In such instances, initial management decisions must be made without the benefit of laboratory testing. In patients with TTP, inhibit …
Metformin-induced TTP mediates communication between Kupffer cells and hepatocytes to alleviate hepatic steatosis by regulating lipophagy and necroptosis.
Park J, Rah SY, An HS, Lee JY, Roh GS, Ryter SW, Park JW, Yang CH, Surh YJ, Kim UH, Chung HT, Joe Y. Park J, et al. Metabolism. 2023 Apr;141:155516. doi: 10.1016/j.metabol.2023.155516. Epub 2023 Feb 10. Metabolism. 2023. PMID: 36773805 Free article.
Lipid accumulation and cell death were evaluated in co-culture systems with primary hepatocytes and KCs derived from either Ttp(+/+) or Ttp(-/-) mice. RESULTS: Tristetraprolin (TTP), an mRNA binding protein, was essential for the protective effects of metform …
Lipid accumulation and cell death were evaluated in co-culture systems with primary hepatocytes and KCs derived from either Ttp(+/+) …
TTP-like syndrome: novel concept and molecular pathogenesis of endotheliopathy-associated vascular microthrombotic disease.
Chang JC. Chang JC. Thromb J. 2018 Aug 11;16:20. doi: 10.1186/s12959-018-0174-4. eCollection 2018. Thromb J. 2018. PMID: 30127669 Free PMC article. Review.
Vascular microthrombotic disease (VMTD) includes both TTP and TTP-like syndrome because their underlying pathology is the same disseminated intravascular microthrombosis (DIT). ...Thus, this author's contention is TTP and TTP-like syndrome are two dist …
Vascular microthrombotic disease (VMTD) includes both TTP and TTP-like syndrome because their underlying pathology is the same …
Unresponsive Thrombotic Thrombocytopenic Purpura (TTP): Challenges and Solutions.
Lemiale V, Valade S, Mariotte E. Lemiale V, et al. Ther Clin Risk Manag. 2021 Jun 3;17:577-587. doi: 10.2147/TCRM.S205632. eCollection 2021. Ther Clin Risk Manag. 2021. PMID: 34113115 Free PMC article. Review.
As patients with unresponsive TTP are at increased risk of mortality, prompt recognition and early therapeutic intensification are mandatory. ...In this work, we focus on possible therapies for the management of patients with unresponsive TTP, and propose an algorit …
As patients with unresponsive TTP are at increased risk of mortality, prompt recognition and early therapeutic intensification are ma …
Thrombotic thrombocytopenic purpura.
Joly BS, Coppo P, Veyradier A. Joly BS, et al. Blood. 2017 May 25;129(21):2836-2846. doi: 10.1182/blood-2016-10-709857. Epub 2017 Apr 17. Blood. 2017. PMID: 28416507 Free article. Review.
In rare cases, however, TTP begins as soon as childhood, with frequent inherited forms. ...Rapid recognition of TTP is crucial to initiate appropriate treatment. The first-line therapy for acute TTP is based on daily therapeutic plasma exchange supplying defi …
In rare cases, however, TTP begins as soon as childhood, with frequent inherited forms. ...Rapid recognition of TTP is crucial …
Clinical implications of tristetraprolin (TTP) modulation in the treatment of inflammatory diseases.
Snyder BL, Blackshear PJ. Snyder BL, et al. Pharmacol Ther. 2022 Nov;239:108198. doi: 10.1016/j.pharmthera.2022.108198. Epub 2022 May 5. Pharmacol Ther. 2022. PMID: 35525391 Free PMC article. Review.
To investigate the possibility that increased TTP expression or activity might have a beneficial effect on inflammatory diseases, at least two mouse models have been developed that provide proof of principle that increasing TTP activity can promote the decay of pro- …
To investigate the possibility that increased TTP expression or activity might have a beneficial effect on inflammatory diseases, at …
Severe Thrombotic Thrombocytopenic Purpura (TTP) with Organ Failure in Critically Ill Patients.
Fodil S, Zafrani L. Fodil S, et al. J Clin Med. 2022 Feb 19;11(4):1103. doi: 10.3390/jcm11041103. J Clin Med. 2022. PMID: 35207375 Free PMC article. Review.
Acute kidney injury, although usually less severe than that in hemolytic and uremic syndrome, is common during TTP. Initial management in the ICU should always be considered in TTP patients. ...ICU management permits close monitoring and the rapid introduction of li …
Acute kidney injury, although usually less severe than that in hemolytic and uremic syndrome, is common during TTP. Initial managemen …
An update on pathogenesis and diagnosis of thrombotic thrombocytopenic purpura.
Joly BS, Coppo P, Veyradier A. Joly BS, et al. Expert Rev Hematol. 2019 Jun;12(6):383-395. doi: 10.1080/17474086.2019.1611423. Epub 2019 May 20. Expert Rev Hematol. 2019. PMID: 31107120 Review.
ADAMTS13 deficiency is congenital or acquired. Several targets are used in TTP treatment. Expert opinion: Differential diagnosis of TTP may be challenging and ADAMTS13 investigations are needed. ADAMTS13 conformation could be a promising parameter for TTP dia …
ADAMTS13 deficiency is congenital or acquired. Several targets are used in TTP treatment. Expert opinion: Differential diagnosis of …
Cataloguing the phosphorylation sites of tristetraprolin (TTP): Functional implications for inflammatory diseases.
Rezcallah MC, Al-Mazi T, Ammit AJ. Rezcallah MC, et al. Cell Signal. 2021 Feb;78:109868. doi: 10.1016/j.cellsig.2020.109868. Epub 2020 Dec 1. Cell Signal. 2021. PMID: 33276085 Review.
TTP expression, regulation and function is controlled by phosphorylation. ...In order to propel investigation of TTP and fully exploit its potential as a drug target in inflammatory disease, this review will catalogue TTP phosphorylation sites in both the mur …
TTP expression, regulation and function is controlled by phosphorylation. ...In order to propel investigation of TTP and fully …
HIV-associated thrombotic thrombocytopenic purpura (HIV-TTP): A practical guide and review of the literature.
Louw S, Jacobson BF, Wiggill TM, Chapanduka Z, Sarah Mayne E. Louw S, et al. HIV Med. 2022 Nov;23(10):1033-1040. doi: 10.1111/hiv.13305. Epub 2022 Apr 3. HIV Med. 2022. PMID: 35373442 Free PMC article. Review.
The exact pathogenesis of HIV-associated TTP (HIV-TTP) is however still unclear with diagnostic and therapeutic inconsistancies. METHODS: A systematic review of the published literature regarding HIV-TTP was performed. RESULTS: HIV-TTP is still associa …
The exact pathogenesis of HIV-associated TTP (HIV-TTP) is however still unclear with diagnostic and therapeutic inconsistancie …
10,209 results
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