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An Organoid Biobank of Neuroendocrine Neoplasms Enables Genotype-Phenotype Mapping.
Kawasaki K, Toshimitsu K, Matano M, Fujita M, Fujii M, Togasaki K, Ebisudani T, Shimokawa M, Takano A, Takahashi S, Ohta Y, Nanki K, Igarashi R, Ishimaru K, Ishida H, Sukawa Y, Sugimoto S, Saito Y, Maejima K, Sasagawa S, Lee H, Kim HG, Ha K, Hamamoto J, Fukunaga K, Maekawa A, Tanabe M, Ishihara S, Hamamoto Y, Yasuda H, Sekine S, Kudo A, Kitagawa Y, Kanai T, Nakagawa H, Sato T. Kawasaki K, et al. Among authors: takahashi s. Cell. 2020 Nov 25;183(5):1420-1435.e21. doi: 10.1016/j.cell.2020.10.023. Epub 2020 Nov 6. Cell. 2020. PMID: 33159857 Free article.
Human Pancreatic Tumor Organoids Reveal Loss of Stem Cell Niche Factor Dependence during Disease Progression.
Seino T, Kawasaki S, Shimokawa M, Tamagawa H, Toshimitsu K, Fujii M, Ohta Y, Matano M, Nanki K, Kawasaki K, Takahashi S, Sugimoto S, Iwasaki E, Takagi J, Itoi T, Kitago M, Kitagawa Y, Kanai T, Sato T. Seino T, et al. Among authors: takahashi s. Cell Stem Cell. 2018 Mar 1;22(3):454-467.e6. doi: 10.1016/j.stem.2017.12.009. Epub 2018 Jan 11. Cell Stem Cell. 2018. PMID: 29337182 Free article.
Divergent Routes toward Wnt and R-spondin Niche Independency during Human Gastric Carcinogenesis.
Nanki K, Toshimitsu K, Takano A, Fujii M, Shimokawa M, Ohta Y, Matano M, Seino T, Nishikori S, Ishikawa K, Kawasaki K, Togasaki K, Takahashi S, Sukawa Y, Ishida H, Sugimoto S, Kawakubo H, Kim J, Kitagawa Y, Sekine S, Koo BK, Kanai T, Sato T. Nanki K, et al. Among authors: takahashi s. Cell. 2018 Aug 9;174(4):856-869.e17. doi: 10.1016/j.cell.2018.07.027. Cell. 2018. PMID: 30096312 Free article.
Somatic inflammatory gene mutations in human ulcerative colitis epithelium.
Nanki K, Fujii M, Shimokawa M, Matano M, Nishikori S, Date S, Takano A, Toshimitsu K, Ohta Y, Takahashi S, Sugimoto S, Ishimaru K, Kawasaki K, Nagai Y, Ishii R, Yoshida K, Sasaki N, Hibi T, Ishihara S, Kanai T, Sato T. Nanki K, et al. Among authors: takahashi s. Nature. 2020 Jan;577(7789):254-259. doi: 10.1038/s41586-019-1844-5. Epub 2019 Dec 18. Nature. 2020. PMID: 31853059
Wnt Signaling Shapes the Histologic Variation in Diffuse Gastric Cancer.
Togasaki K, Sugimoto S, Ohta Y, Nanki K, Matano M, Takahashi S, Fujii M, Kanai T, Sato T. Togasaki K, et al. Among authors: takahashi s. Gastroenterology. 2021 Feb;160(3):823-830. doi: 10.1053/j.gastro.2020.10.047. Epub 2020 Nov 17. Gastroenterology. 2021. PMID: 33217450 Free article.
An organoid-based organ-repurposing approach to treat short bowel syndrome.
Sugimoto S, Kobayashi E, Fujii M, Ohta Y, Arai K, Matano M, Ishikawa K, Miyamoto K, Toshimitsu K, Takahashi S, Nanki K, Hakamata Y, Kanai T, Sato T. Sugimoto S, et al. Among authors: takahashi s. Nature. 2021 Apr;592(7852):99-104. doi: 10.1038/s41586-021-03247-2. Epub 2021 Feb 24. Nature. 2021. PMID: 33627870
Identification of Quiescent LGR5+ Stem Cells in the Human Colon.
Ishikawa K, Sugimoto S, Oda M, Fujii M, Takahashi S, Ohta Y, Takano A, Ishimaru K, Matano M, Yoshida K, Hanyu H, Toshimitsu K, Sawada K, Shimokawa M, Saito M, Kawasaki K, Ishii R, Taniguchi K, Imamura T, Kanai T, Sato T. Ishikawa K, et al. Among authors: takahashi s. Gastroenterology. 2022 Nov;163(5):1391-1406.e24. doi: 10.1053/j.gastro.2022.07.081. Epub 2022 Aug 11. Gastroenterology. 2022. PMID: 35963362 Free article.
Cell-matrix interface regulates dormancy in human colon cancer stem cells.
Ohta Y, Fujii M, Takahashi S, Takano A, Nanki K, Matano M, Hanyu H, Saito M, Shimokawa M, Nishikori S, Hatano Y, Ishii R, Sawada K, Machinaga A, Ikeda W, Imamura T, Sato T. Ohta Y, et al. Among authors: takahashi s. Nature. 2022 Aug;608(7924):784-794. doi: 10.1038/s41586-022-05043-y. Epub 2022 Jul 7. Nature. 2022. PMID: 35798028
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