Takakura T - Search Results

1

Batch production of deacetyl 7-aminocephalosporanic acid by immobilized cephalosporin-C deacetylase.

Takimoto A, Takakura T, Tani H, Yagi S, Mitsushima K. Takimoto A, et al. Among authors: takakura t. Appl Microbiol Biotechnol. 2004 Aug;65(3):263-7. doi: 10.1007/s00253-004-1595-5. Epub 2004 Apr 7. Appl Microbiol Biotechnol. 2004. PMID: 15069587

2

High-level expression and bulk crystallization of recombinant L-methionine gamma-lyase, an anticancer agent.

Takakura T, Ito T, Yagi S, Notsu Y, Itakura T, Nakamura T, Inagaki K, Esaki N, Hoffman RM, Takimoto A. Takakura T, et al. Appl Microbiol Biotechnol. 2006 Mar;70(2):183-92. doi: 10.1007/s00253-005-0038-2. Epub 2005 Jul 13. Appl Microbiol Biotechnol. 2006. PMID: 16012835

3

Assay method for antitumor L-methionine gamma-lyase: comprehensive kinetic analysis of the complex reaction with L-methionine.

Takakura T, Mitsushima K, Yagi S, Inagaki K, Tanaka H, Esaki N, Soda K, Takimoto A. Takakura T, et al. Anal Biochem. 2004 Apr 15;327(2):233-40. doi: 10.1016/j.ab.2004.01.024. Anal Biochem. 2004. PMID: 15051540

4

Development of Recombinant Methioninase for Cancer Treatment.

Hoffman RM, Tan Y, Li S, Han Q, Yagi S, Takakura T, Takimoto A, Inagaki K, Kudou D. Hoffman RM, et al. Among authors: takakura t. Methods Mol Biol. 2019;1866:107-131. doi: 10.1007/978-1-4939-8796-2_10. Methods Mol Biol. 2019. PMID: 30725412

5

Physicochemical and pharmacokinetic characterization of highly potent recombinant L-methionine gamma-lyase conjugated with polyethylene glycol as an antitumor agent.

Takakura T, Takimoto A, Notsu Y, Yoshida H, Ito T, Nagatome H, Ohno M, Kobayashi Y, Yoshioka T, Inagaki K, Yagi S, Hoffman RM, Esaki N. Takakura T, et al. Cancer Res. 2006 Mar 1;66(5):2807-14. doi: 10.1158/0008-5472.CAN-05-3910. Cancer Res. 2006. PMID: 16510603

6

Chemoenzymatic synthesis of glycosylated glucagon-like peptide 1: effect of glycosylation on proteolytic resistance and in vivo blood glucose-lowering activity.

Ueda T, Tomita K, Notsu Y, Ito T, Fumoto M, Takakura T, Nagatome H, Takimoto A, Mihara S, Togame H, Kawamoto K, Iwasaki T, Asakura K, Oshima T, Hanasaki K, Nishimura S, Kondo H. Ueda T, et al. Among authors: takakura t. J Am Chem Soc. 2009 May 6;131(17):6237-45. doi: 10.1021/ja900261g. J Am Chem Soc. 2009. PMID: 19361194

7

Structure of the antitumour enzyme L-methionine gamma-lyase from Pseudomonas putida at 1.8 A resolution.

Kudou D, Misaki S, Yamashita M, Tamura T, Takakura T, Yoshioka T, Yagi S, Hoffman RM, Takimoto A, Esaki N, Inagaki K. Kudou D, et al. Among authors: takakura t. J Biochem. 2007 Apr;141(4):535-44. doi: 10.1093/jb/mvm055. Epub 2007 Feb 8. J Biochem. 2007. PMID: 17289792

8

PEGylation confers greatly extended half-life and attenuated immunogenicity to recombinant methioninase in primates.

Yang Z, Wang J, Lu Q, Xu J, Kobayashi Y, Takakura T, Takimoto A, Yoshioka T, Lian C, Chen C, Zhang D, Zhang Y, Li S, Sun X, Tan Y, Yagi S, Frenkel EP, Hoffman RM. Yang Z, et al. Among authors: takakura t. Cancer Res. 2004 Sep 15;64(18):6673-8. doi: 10.1158/0008-5472.CAN-04-1822. Cancer Res. 2004. PMID: 15374983

9

Circulating half-life of PEGylated recombinant methioninase holoenzyme is highly dose dependent on cofactor pyridoxal-5'-phosphate.

Yang Z, Sun X, Li S, Tan Y, Wang X, Zhang N, Yagi S, Takakura T, Kobayashi Y, Takimoto A, Yoshioka T, Suginaka A, Frenkel EP, Hoffman RM. Yang Z, et al. Among authors: takakura t. Cancer Res. 2004 Aug 15;64(16):5775-8. doi: 10.1158/0008-5472.CAN-04-1406. Cancer Res. 2004. PMID: 15313919

10

Endogenous angiogenesis inhibitor vasohibin1 exhibits broad-spectrum antilymphangiogenic activity and suppresses lymph node metastasis.

Heishi T, Hosaka T, Suzuki Y, Miyashita H, Oike Y, Takahashi T, Nakamura T, Arioka S, Mitsuda Y, Takakura T, Hojo K, Matsumoto M, Yamauchi C, Ohta H, Sonoda H, Sato Y. Heishi T, et al. Among authors: takakura t. Am J Pathol. 2010 Apr;176(4):1950-8. doi: 10.2353/ajpath.2010.090829. Epub 2010 Feb 4. Am J Pathol. 2010. PMID: 20133819 Free PMC article.

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