A genome-wide association study identifies a novel association between SDC3 and apparent treatment-resistant hypertension.
Xiao X, Li R, Wu C, Yan Y, Yuan M, Cui B, Zhang Y, Zhang C, Zhang X, Zhang W, Hui R, Wang Y.
Xiao X, et al.
BMC Med. 2022 Nov 30;20(1):463. doi: 10.1186/s12916-022-02665-x.
BMC Med. 2022.
PMID: 36447229
Free PMC article.
RESULTS: The GWAS in first cohort revealed four suggestive loci (1p35, 4q13.2-21.1, 5q22-23.2, and 15q11.1-q12) represented by 23 SNPs. The 23 significant SNPs were in or near LAPTM5, SDC3, UGT2A1, FTMT, and NIPA1. eQTL analysis uncovered 14 SNPs in 1p35 locus all had same …
RESULTS: The GWAS in first cohort revealed four suggestive loci (1p35, 4q13.2-21.1, 5q22-23.2, and 15q11.1-q12) represented by 23 SNPs. The …