Vestweber D - Search Results

1

Targeting VE-PTP activates TIE2 and stabilizes the ocular vasculature.

Shen J, Frye M, Lee BL, Reinardy JL, McClung JM, Ding K, Kojima M, Xia H, Seidel C, Lima e Silva R, Dong A, Hackett SF, Wang J, Howard BW, Vestweber D, Kontos CD, Peters KG, Campochiaro PA. Shen J, et al. Among authors: vestweber d. J Clin Invest. 2014 Oct;124(10):4564-76. doi: 10.1172/JCI74527. Epub 2014 Sep 2. J Clin Invest. 2014. PMID: 25180601 Free PMC article.

2

Dissociation of VE-PTP from VE-cadherin is required for leukocyte extravasation and for VEGF-induced vascular permeability in vivo.

Broermann A, Winderlich M, Block H, Frye M, Rossaint J, Zarbock A, Cagna G, Linnepe R, Schulte D, Nottebaum AF, Vestweber D. Broermann A, et al. Among authors: vestweber d. J Exp Med. 2011 Nov 21;208(12):2393-401. doi: 10.1084/jem.20110525. Epub 2011 Oct 24. J Exp Med. 2011. PMID: 22025303 Free PMC article.

3

Integrin β1 controls VE-cadherin localization and blood vessel stability.

Yamamoto H, Ehling M, Kato K, Kanai K, van Lessen M, Frye M, Zeuschner D, Nakayama M, Vestweber D, Adams RH. Yamamoto H, et al. Among authors: vestweber d. Nat Commun. 2015 Mar 10;6:6429. doi: 10.1038/ncomms7429. Nat Commun. 2015. PMID: 25752958 Free article.

4

Interfering with VE-PTP stabilizes endothelial junctions in vivo via Tie-2 in the absence of VE-cadherin.

Frye M, Dierkes M, Küppers V, Vockel M, Tomm J, Zeuschner D, Rossaint J, Zarbock A, Koh GY, Peters K, Nottebaum AF, Vestweber D. Frye M, et al. Among authors: vestweber d. J Exp Med. 2015 Dec 14;212(13):2267-87. doi: 10.1084/jem.20150718. Epub 2015 Dec 7. J Exp Med. 2015. PMID: 26642851 Free PMC article.

5

Reversible retinal vessel closure from VEGF-induced leukocyte plugging.

Liu Y, Shen J, Fortmann SD, Wang J, Vestweber D, Campochiaro PA. Liu Y, et al. Among authors: vestweber d. JCI Insight. 2017 Sep 21;2(18):e95530. doi: 10.1172/jci.insight.95530. eCollection 2017 Sep 21. JCI Insight. 2017. PMID: 28931763 Free PMC article.

6

Context-dependent functions of angiopoietin 2 are determined by the endothelial phosphatase VEPTP.

Souma T, Thomson BR, Heinen S, Carota IA, Yamaguchi S, Onay T, Liu P, Ghosh AK, Li C, Eremina V, Hong YK, Economides AN, Vestweber D, Peters KG, Jin J, Quaggin SE. Souma T, et al. Among authors: vestweber d. Proc Natl Acad Sci U S A. 2018 Feb 6;115(6):1298-1303. doi: 10.1073/pnas.1714446115. Epub 2018 Jan 22. Proc Natl Acad Sci U S A. 2018. PMID: 29358379 Free PMC article.

7

VE-PTP inhibition stabilizes endothelial junctions by activating FGD5.

Braun LJ, Zinnhardt M, Vockel M, Drexler HC, Peters K, Vestweber D. Braun LJ, et al. Among authors: vestweber d. EMBO Rep. 2019 Jul;20(7):e47046. doi: 10.15252/embr.201847046. Epub 2019 May 14. EMBO Rep. 2019. PMID: 31267715 Free PMC article.

8

Vascular Endothelial Receptor Tyrosine Phosphatase: Identification of Novel Substrates Related to Junctions and a Ternary Complex with EPHB4 and TIE2.

Drexler HCA, Vockel M, Polaschegg C, Frye M, Peters K, Vestweber D. Drexler HCA, et al. Among authors: vestweber d. Mol Cell Proteomics. 2019 Oct;18(10):2058-2077. doi: 10.1074/mcp.RA119.001716. Epub 2019 Aug 19. Mol Cell Proteomics. 2019. PMID: 31427368 Free PMC article.

9

A Small Molecule Inhibitor of VE-PTP Activates Tie2 in Schlemm's Canal Increasing Outflow Facility and Reducing Intraocular Pressure.

Li G, Nottebaum AF, Brigell M, Navarro ID, Ipe U, Mishra S, Gomez-Caraballo M, Schmitt H, Soldo B, Pakola S, Withers B, Peters KG, Vestweber D, Stamer WD. Li G, et al. Among authors: vestweber d. Invest Ophthalmol Vis Sci. 2020 Dec 1;61(14):12. doi: 10.1167/iovs.61.14.12. Invest Ophthalmol Vis Sci. 2020. PMID: 33315051 Free PMC article. Clinical Trial.

10

[No title available]

[No authors listed] [No authors listed] PMID: 33451478

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