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Hsp90 in Cancer: Transcriptional Roles in the Nucleus.
Calderwood SK, Neckers L. Calderwood SK, et al. Adv Cancer Res. 2016;129:89-106. doi: 10.1016/bs.acr.2015.08.002. Epub 2015 Oct 12. Adv Cancer Res. 2016. PMID: 26916002 Free PMC article. Review.
Phase I study of the heat shock protein 90 (Hsp90) inhibitor onalespib (AT13387) administered on a daily for 2 consecutive days per week dosing schedule in patients with advanced solid tumors.
Do K, Speranza G, Chang LC, Polley EC, Bishop R, Zhu W, Trepel JB, Lee S, Lee MJ, Kinders RJ, Phillips L, Collins J, Lyons J, Jeong W, Antony R, Chen AP, Neckers L, Doroshow JH, Kummar S. Do K, et al. Invest New Drugs. 2015 Aug;33(4):921-30. doi: 10.1007/s10637-015-0255-1. Epub 2015 Jun 18. Invest New Drugs. 2015. PMID: 26082332 Free PMC article. Clinical Trial.
Detecting HSP90 phosphorylation.
Mollapour M, Neckers L. Mollapour M, et al. Methods Mol Biol. 2011;787:67-74. doi: 10.1007/978-1-61779-295-3_5. Methods Mol Biol. 2011. PMID: 21898227 Free PMC article.
Hsp90 phosphorylation, Wee1 and the cell cycle.
Mollapour M, Tsutsumi S, Neckers L. Mollapour M, et al. Cell Cycle. 2010 Jun 15;9(12):2310-6. doi: 10.4161/cc.9.12.12054. Epub 2010 Jun 15. Cell Cycle. 2010. PMID: 20519952 Free PMC article.