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124,452 results

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Rapid and efficient clathrin-mediated endocytosis revealed in genome-edited mammalian cells.
Doyon JB, Zeitler B, Cheng J, Cheng AT, Cherone JM, Santiago Y, Lee AH, Vo TD, Doyon Y, Miller JC, Paschon DE, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Drubin DG. Doyon JB, et al. Among authors: zhang l. Nat Cell Biol. 2011 Mar;13(3):331-7. doi: 10.1038/ncb2175. Epub 2011 Feb 6. Nat Cell Biol. 2011. PMID: 21297641 Free PMC article.
Targeted genome editing across species using ZFNs and TALENs.
Wood AJ, Lo TW, Zeitler B, Pickle CS, Ralston EJ, Lee AH, Amora R, Miller JC, Leung E, Meng X, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Meyer BJ. Wood AJ, et al. Among authors: zhang l. Science. 2011 Jul 15;333(6040):307. doi: 10.1126/science.1207773. Epub 2011 Jun 23. Science. 2011. PMID: 21700836 Free PMC article.
Improved specificity of TALE-based genome editing using an expanded RVD repertoire.
Miller JC, Zhang L, Xia DF, Campo JJ, Ankoudinova IV, Guschin DY, Babiarz JE, Meng X, Hinkley SJ, Lam SC, Paschon DE, Vincent AI, Dulay GP, Barlow KA, Shivak DA, Leung E, Kim JD, Amora R, Urnov FD, Gregory PD, Rebar EJ. Miller JC, et al. Among authors: zhang l. Nat Methods. 2015 May;12(5):465-71. doi: 10.1038/nmeth.3330. Epub 2015 Mar 23. Nat Methods. 2015. PMID: 25799440
Precise genome modification in the crop species Zea mays using zinc-finger nucleases.
Shukla VK, Doyon Y, Miller JC, DeKelver RC, Moehle EA, Worden SE, Mitchell JC, Arnold NL, Gopalan S, Meng X, Choi VM, Rock JM, Wu YY, Katibah GE, Zhifang G, McCaskill D, Simpson MA, Blakeslee B, Greenwalt SA, Butler HJ, Hinkley SJ, Zhang L, Rebar EJ, Gregory PD, Urnov FD. Shukla VK, et al. Among authors: zhang l. Nature. 2009 May 21;459(7245):437-41. doi: 10.1038/nature07992. Epub 2009 Apr 29. Nature. 2009. PMID: 19404259
A TALE nuclease architecture for efficient genome editing.
Miller JC, Tan S, Qiao G, Barlow KA, Wang J, Xia DF, Meng X, Paschon DE, Leung E, Hinkley SJ, Dulay GP, Hua KL, Ankoudinova I, Cost GJ, Urnov FD, Zhang HS, Holmes MC, Zhang L, Gregory PD, Rebar EJ. Miller JC, et al. Among authors: zhang l, zhang hs. Nat Biotechnol. 2011 Feb;29(2):143-8. doi: 10.1038/nbt.1755. Epub 2010 Dec 22. Nat Biotechnol. 2011. PMID: 21179091
Efficient targeted gene disruption in the soma and germ line of the frog Xenopus tropicalis using engineered zinc-finger nucleases.
Young JJ, Cherone JM, Doyon Y, Ankoudinova I, Faraji FM, Lee AH, Ngo C, Guschin DY, Paschon DE, Miller JC, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Harland RM, Zeitler B. Young JJ, et al. Among authors: zhang l. Proc Natl Acad Sci U S A. 2011 Apr 26;108(17):7052-7. doi: 10.1073/pnas.1102030108. Epub 2011 Apr 6. Proc Natl Acad Sci U S A. 2011. PMID: 21471457 Free PMC article.
Generation of isogenic pluripotent stem cells differing exclusively at two early onset Parkinson point mutations.
Soldner F, Laganière J, Cheng AW, Hockemeyer D, Gao Q, Alagappan R, Khurana V, Golbe LI, Myers RH, Lindquist S, Zhang L, Guschin D, Fong LK, Vu BJ, Meng X, Urnov FD, Rebar EJ, Gregory PD, Zhang HS, Jaenisch R. Soldner F, et al. Among authors: zhang l, zhang hs. Cell. 2011 Jul 22;146(2):318-31. doi: 10.1016/j.cell.2011.06.019. Epub 2011 Jul 14. Cell. 2011. PMID: 21757228 Free PMC article.
Functional footprinting of regulatory DNA.
Vierstra J, Reik A, Chang KH, Stehling-Sun S, Zhou Y, Hinkley SJ, Paschon DE, Zhang L, Psatha N, Bendana YR, O'Neil CM, Song AH, Mich AK, Liu PQ, Lee G, Bauer DE, Holmes MC, Orkin SH, Papayannopoulou T, Stamatoyannopoulos G, Rebar EJ, Gregory PD, Urnov FD, Stamatoyannopoulos JA. Vierstra J, et al. Among authors: zhang l. Nat Methods. 2015 Oct;12(10):927-30. doi: 10.1038/nmeth.3554. Epub 2015 Aug 31. Nat Methods. 2015. PMID: 26322838 Free PMC article.
Heritable targeted gene disruption in zebrafish using designed zinc-finger nucleases.
Doyon Y, McCammon JM, Miller JC, Faraji F, Ngo C, Katibah GE, Amora R, Hocking TD, Zhang L, Rebar EJ, Gregory PD, Urnov FD, Amacher SL. Doyon Y, et al. Among authors: zhang l. Nat Biotechnol. 2008 Jun;26(6):702-8. doi: 10.1038/nbt1409. Epub 2008 May 25. Nat Biotechnol. 2008. PMID: 18500334 Free PMC article.
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