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Structure-Guided Design and Synthesis of a Pyridazinone Series of Trypanosoma cruzi Proteasome Inhibitors.
J Med Chem. 2023 Aug 10;66(15):10413-10431. doi: 10.1021/acs.jmedchem.3c00582. Epub 2023 Jul 28.
J Med Chem. 2023.
PMID: 37506194
Free PMC article.
An 18F-Labeled Poly(ADP-ribose) Polymerase Positron Emission Tomography Imaging Agent.
Zmuda F, Blair A, Liuzzi MC, Malviya G, Chalmers AJ, Lewis D, Sutherland A, Pimlott SL.
Zmuda F, et al.
J Med Chem. 2018 May 10;61(9):4103-4114. doi: 10.1021/acs.jmedchem.8b00138. Epub 2018 Apr 19.
J Med Chem. 2018.
PMID: 29630818
Free PMC article.
Item in Clipboard
Synthesis and Evaluation of a Radioiodinated Tracer with Specificity for Poly(ADP-ribose) Polymerase-1 (PARP-1) in Vivo.
Zmuda F, Malviya G, Blair A, Boyd M, Chalmers AJ, Sutherland A, Pimlott SL.
Zmuda F, et al.
J Med Chem. 2015 Nov 12;58(21):8683-93. doi: 10.1021/acs.jmedchem.5b01324. Epub 2015 Oct 27.
J Med Chem. 2015.
PMID: 26469301
Free article.
Item in Clipboard
Accessory proteins of the zDHHC family of S-acylation enzymes.
Salaun C, Locatelli C, Zmuda F, Cabrera González J, Chamberlain LH.
Salaun C, et al. Among authors: zmuda f.
J Cell Sci. 2020 Nov 17;133(22):jcs251819. doi: 10.1242/jcs.251819.
J Cell Sci. 2020.
PMID: 33203738
Free article.
Review.
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Regulatory effects of post-translational modifications on zDHHC S-acyltransferases.
Zmuda F, Chamberlain LH.
Zmuda F, et al.
J Biol Chem. 2020 Oct 23;295(43):14640-14652. doi: 10.1074/jbc.REV120.014717. Epub 2020 Aug 17.
J Biol Chem. 2020.
PMID: 32817054
Free PMC article.
Review.
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Trypanosoma cruzi Phosphomannomutase and Guanosine Diphosphate-Mannose Pyrophosphorylase Ligandability Assessment.
Zmuda F, Shepherd SM, Ferguson MAJ, Gray DW, Torrie LS, De Rycker M.
Zmuda F, et al.
Antimicrob Agents Chemother. 2019 Sep 23;63(10):e01082-19. doi: 10.1128/AAC.01082-19. Print 2019 Oct.
Antimicrob Agents Chemother. 2019.
PMID: 31405854
Free PMC article.
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Identification of Novel Trypanosoma cruzi Proteasome Inhibitors Using a Luminescence-Based High-Throughput Screening Assay.
Zmuda F, Sastry L, Shepherd SM, Jones D, Scott A, Craggs PD, Cortes A, Gray DW, Torrie LS, De Rycker M.
Zmuda F, et al.
Antimicrob Agents Chemother. 2019 Aug 23;63(9):e00309-19. doi: 10.1128/AAC.00309-19. Print 2019 Sep.
Antimicrob Agents Chemother. 2019.
PMID: 31307977
Free PMC article.
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A novel 18F-labelled high affinity agent for PET imaging of the translocator protein.
Blair A, Zmuda F, Malviya G, Tavares AAS, Tamagnan GD, Chalmers AJ, Dewar D, Pimlott SL, Sutherland A.
Blair A, et al. Among authors: zmuda f.
Chem Sci. 2015 Aug 1;6(8):4772-4777. doi: 10.1039/c5sc01647a. Epub 2015 May 27.
Chem Sci. 2015.
PMID: 29142713
Free PMC article.
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