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Page 1
S-amlodipine-bisoprolol combination therapy caused elevated transaminases and triglyceride levels in healthy Chinese subjects: a randomized controlled, open-label, multiple-dose pharmacokinetic interaction study.
Liu J, Li X, Zhang H, Liu Y, Wu M, Niu J, Ding Y. Liu J, et al. Expert Opin Drug Metab Toxicol. 2019 Sep;15(9):687-695. doi: 10.1080/17425255.2019.1650913. Epub 2019 Aug 7. Expert Opin Drug Metab Toxicol. 2019. PMID: 31359804 Clinical Trial.
Introduction: S-amlodipine is main anti-hypertensive active enantiomer of amlodipine. Bisoprolol is a beta-blocker particularly suitable for hypertensive patients with sinus tachycardia. ...
Introduction: S-amlodipine is main anti-hypertensive active enantiomer of amlodipine. Bisoprolol is a beta-blocker particularl …
Simultaneous determination of amlodipine and bisoprolol in rat plasma by a liquid chromatography/tandem mass spectrometry method and its application in pharmacokinetic study.
Chang H, Li J, Li J, Guan X, Sun F, Qian Z, Bi K, Fan G. Chang H, et al. J Pharm Biomed Anal. 2012 Dec;71:104-10. doi: 10.1016/j.jpba.2012.08.012. Epub 2012 Aug 19. J Pharm Biomed Anal. 2012. PMID: 22947502
Multiple reacting monitoring (MRM) transitions of m/z [M+H](+) 409.1237.9 (amlodipine), m/z [M+H](+) 326.2116.0 (bisoprolol) and m/z [M+H](+) 277.0203.0 (clenbuterol, IS) were used to quantify amlodipine, bisoprolol and IS, respectively. The method was sensitive wit …
Multiple reacting monitoring (MRM) transitions of m/z [M+H](+) 409.1237.9 (amlodipine), m/z [M+H](+) 326.2116.0 (bisoprolol) and m/z [M+H](+ …
Clinical and molecular approaches to individualize antihypertensive drug therapy.
Hiltunen TP, Kontula K. Hiltunen TP, et al. Ann Med. 2012 Jun;44 Suppl 1:S23-9. doi: 10.3109/07853890.2012.679960. Ann Med. 2012. PMID: 22713145 Review.
In this placebo-controlled, double-blinded, and randomized study, more than 200 male subjects with essential hypertension were treated with four antihypertensive drug monotherapies (amlodipine, bisoprolol, hydrochlorothiazide, and losartan) in a cross-over fashion, …
In this placebo-controlled, double-blinded, and randomized study, more than 200 male subjects with essential hypertension were treated with …
Laboratory tests as predictors of the antihypertensive effects of amlodipine, bisoprolol, hydrochlorothiazide and losartan in men: results from the randomized, double-blind, crossover GENRES Study.
Suonsyrjä T, Hannila-Handelberg T, Paavonen KJ, Miettinen HE, Donner K, Strandberg T, Tikkanen I, Tilvis R, Pentikäinen PJ, Kontula K, Hiltunen TP. Suonsyrjä T, et al. J Hypertens. 2008 Jun;26(6):1250-6. doi: 10.1097/HJH.0b013e3282fcc37f. J Hypertens. 2008. PMID: 18475165 Clinical Trial.
Investigation of the Effects of Some Cardiovascular Drugs on Angiogenesis by Transgenic Zebrafish.
Lv H, Liu B, Qin Y. Lv H, et al. Mediators Inflamm. 2023 Apr 24;2023:1958046. doi: 10.1155/2023/1958046. eCollection 2023. Mediators Inflamm. 2023. PMID: 37138666 Free PMC article.
RESULTS: We found that 6 drugs including isosorbide mononitrate, amlodipine, bisoprolol fumarate, carvedilol, irbesartan, and rosuvastatin calcium may affect angiogenesis by vascular endothelial growth factor (VEGF) signaling pathway. ...
RESULTS: We found that 6 drugs including isosorbide mononitrate, amlodipine, bisoprolol fumarate, carvedilol, irbesartan, and …
Effects of antihypertensive treatment on plasma apelin, resistin, and visfatin concentrations.
Skoczylas A, Piecha G, Więcek A. Skoczylas A, et al. Pol Arch Med Wewn. 2016 Apr 29;126(4):243-53. doi: 10.20452/pamw.3390. Epub 2016 Apr 29. Pol Arch Med Wewn. 2016. PMID: 27129086 Free article.
Mean daily plasma resistin concentrations were significantly lower after 6-week treatment with amlodipine, bisoprolol, or indapamide compared with the baseline values. ...
Mean daily plasma resistin concentrations were significantly lower after 6-week treatment with amlodipine, bisoprolol, or inda …
Effects of four different antihypertensive drugs on plasma metabolomic profiles in patients with essential hypertension.
Hiltunen TP, Rimpelä JM, Mohney RP, Stirdivant SM, Kontula KK. Hiltunen TP, et al. PLoS One. 2017 Nov 9;12(11):e0187729. doi: 10.1371/journal.pone.0187729. eCollection 2017. PLoS One. 2017. PMID: 29121091 Free PMC article. Clinical Trial.
Hypertensive men received in a double-blind rotational fashion amlodipine, bisoprolol, hydrochlorothiazide and losartan, each as a monotherapy for one month, with intervening one-month placebo cycles. ...
Hypertensive men received in a double-blind rotational fashion amlodipine, bisoprolol, hydrochlorothiazide and losartan, each …
Evaluation and analytical applicability of a novel volumetric absorptive microsampling strategy for adherence monitoring of antihypertensive drugs by means of LC-HRMS/MS.
Jacobs CM, Kunz M, Mahfoud F, Wagmann L, Meyer MR. Jacobs CM, et al. Anal Chim Acta. 2021 Dec 1;1187:339137. doi: 10.1016/j.aca.2021.339137. Epub 2021 Oct 5. Anal Chim Acta. 2021. PMID: 34753562
This study aimed to develop and evaluate a VAMS-based strategy for quantifying ten frequently prescribed antihypertensive drugs (AHD) (amlodipine, bisoprolol, candesartan, carvedilol, lercanidipine, losartan carboxylic acid, metoprolol, nebivolol, telmisartan, valsa …
This study aimed to develop and evaluate a VAMS-based strategy for quantifying ten frequently prescribed antihypertensive drugs (AHD) (am …
14 results