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Year Number of Results
1946 3
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1948 7
1949 6
1950 8
1951 14
1952 4
1953 11
1954 4
1955 5
1956 4
1957 9
1958 2
1959 2
1960 3
1961 3
1962 6
1963 9
1964 4
1965 9
1966 8
1967 7
1968 11
1969 13
1970 15
1971 19
1972 21
1973 31
1974 35
1975 179
1976 184
1977 177
1978 170
1979 195
1980 200
1981 221
1982 306
1983 349
1984 366
1985 391
1986 449
1987 379
1988 396
1989 468
1990 475
1991 454
1992 480
1993 437
1994 426
1995 494
1996 521
1997 473
1998 554
1999 499
2000 508
2001 554
2002 545
2003 562
2004 599
2005 627
2006 709
2007 737
2008 752
2009 773
2010 829
2011 812
2012 926
2013 940
2014 938
2015 920
2016 952
2017 950
2018 856
2019 841
2020 906
2021 865
2022 837
2023 640
2024 350

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Page 1
Showing results for amide alone
Your search for ampidexalone retrieved no results
Paracetamol (Acetaminophen) and the Developing Brain.
Bührer C, Endesfelder S, Scheuer T, Schmitz T. Bührer C, et al. Int J Mol Sci. 2021 Oct 15;22(20):11156. doi: 10.3390/ijms222011156. Int J Mol Sci. 2021. PMID: 34681816 Free PMC article. Review.
Altered behavior has been demonstrated in offspring of paracetamol-gavaged pregnant rats, and paracetamol given at or prior to day 10 of life to newborn mice resulted in altered locomotor activity in response to a novel home environment in adulthood and blunted the …
Altered behavior has been demonstrated in offspring of paracetamol-gavaged pregnant rats, and paracetamol given at or prior to day 10 of lif …
Harnessing and engineering amide bond forming ligases for the synthesis of amides.
Winn M, Richardson SM, Campopiano DJ, Micklefield J. Winn M, et al. Curr Opin Chem Biol. 2020 Apr;55:77-85. doi: 10.1016/j.cbpa.2019.12.004. Epub 2020 Feb 12. Curr Opin Chem Biol. 2020. PMID: 32058241 Review.
The amide functional group is ubiquitous in nature and one of the most important motifs in pharmaceuticals, agrochemicals, and other valuable products. ...In this review, we discuss recent research into the discovery, characterization, and development of amide bond …
The amide functional group is ubiquitous in nature and one of the most important motifs in pharmaceuticals, agrochemicals, and other …
Aliskiren.
Anderson DL. Anderson DL. Drugs Today (Barc). 2007 Dec;43(12):849-55. doi: 10.1358/dot.2007.43.12.977448. Drugs Today (Barc). 2007. PMID: 18174970 Review.
Aliskiren (CGP-60536 or SPP100) is the first oral direct renin inhibitor and the first new class of antihypertensive agents to be introduced in more than a decade. Aliskiren taken once a day, alone or in combination with other antihypertensive agents, has been shown to be …
Aliskiren (CGP-60536 or SPP100) is the first oral direct renin inhibitor and the first new class of antihypertensive agents to be introduced …
A stand-alone adenylation domain forms amide bonds in streptothricin biosynthesis.
Maruyama C, Toyoda J, Kato Y, Izumikawa M, Takagi M, Shin-ya K, Katano H, Utagawa T, Hamano Y. Maruyama C, et al. Nat Chem Biol. 2012 Sep;8(9):791-7. doi: 10.1038/nchembio.1040. Epub 2012 Jul 22. Nat Chem Biol. 2012. PMID: 22820420
Here we describe three unusual nonribosomal peptide synthetases (NRPSs) involved in ST biosynthesis: ORF 5 (a stand-alone adenylation (A) domain), ORF 18 (containing thiolation (T) and condensation (C) domains) and ORF 19 (a stand-alone A domain). ...
Here we describe three unusual nonribosomal peptide synthetases (NRPSs) involved in ST biosynthesis: ORF 5 (a stand-alone adenylation …
Renin inhibitors.
Fisher ND, Meagher EA. Fisher ND, et al. J Clin Hypertens (Greenwich). 2011 Sep;13(9):662-6. doi: 10.1111/j.1751-7176.2011.00514.x. Epub 2011 Jul 27. J Clin Hypertens (Greenwich). 2011. PMID: 21896147 Free PMC article. Review.
Increases in serum potassium >5.5 meq/L were infrequent in patients with essential hypertension treated with aliskiren alone (0.9% compared with 0.6% with placebo)....
Increases in serum potassium >5.5 meq/L were infrequent in patients with essential hypertension treated with aliskiren alone (0.9% …
Immobilized coupling reagents: synthesis of amides/peptides.
Cherkupally P, Ramesh S, de la Torre BG, Govender T, Kruger HG, Albericio F. Cherkupally P, et al. ACS Comb Sci. 2014 Nov 10;16(11):579-601. doi: 10.1021/co500126y. Epub 2014 Oct 24. ACS Comb Sci. 2014. PMID: 25330282 Review.
Herein, we have covered all known supported-coupling reagents and bases which have had a great impact in amide/peptide bond formation. These coupling reagents have been used for the activation of a carboxyl moiety; thus generating an active acylating species that is ready …
Herein, we have covered all known supported-coupling reagents and bases which have had a great impact in amide/peptide bond formation …
Amide I'-II' 2D IR spectroscopy provides enhanced protein secondary structural sensitivity.
Deflores LP, Ganim Z, Nicodemus RA, Tokmakoff A. Deflores LP, et al. J Am Chem Soc. 2009 Mar 11;131(9):3385-91. doi: 10.1021/ja8094922. J Am Chem Soc. 2009. PMID: 19256572
Polarization-dependent amide I'-II' 2D IR experiments on poly-l-lysine in the beta-sheet, alpha-helix, and random coil conformations show that a combination of amide I' and II' diagonal and cross peaks can effectively distinguish between secondary structural content …
Polarization-dependent amide I'-II' 2D IR experiments on poly-l-lysine in the beta-sheet, alpha-helix, and random coil conformations …
Charge-Free, Stabilizing Amide-pi Interactions Can Be Used to Control Collagen Triple-Helix Self-Assembly.
Walker DR, Alizadehmojarad AA, Kolomeisky AB, Hartgerink JD. Walker DR, et al. Biomacromolecules. 2021 May 10;22(5):2137-2147. doi: 10.1021/acs.biomac.1c00234. Epub 2021 Apr 21. Biomacromolecules. 2021. PMID: 33881314
While the field has had success using charge-pair interactions and cation-pi interactions in helix design, these alone are not adequate for achieving the degree of specificity desirable for these supramolecular structures. ...Herein, we propose, validate, and utilize pairw …
While the field has had success using charge-pair interactions and cation-pi interactions in helix design, these alone are not adequa …
Amide compound synthesis by adenylation domain of bacillibactin synthetase.
Abe T, Hashimoto Y, Sugimoto S, Kobayashi K, Kumano T, Kobayashi M. Abe T, et al. J Antibiot (Tokyo). 2017 Apr;70(4):435-442. doi: 10.1038/ja.2016.117. Epub 2016 Oct 12. J Antibiot (Tokyo). 2017. PMID: 27731335
The adenylation domain of nonribosomal peptide synthetase (NRPS) is responsible for the selective substrate recognition and its activation (as an acyl-O-AMP intermediate) during ATP consumption. DhbE, a stand-alone adenylation domain, acts on an aromatic acid, 2,3-dihydrox …
The adenylation domain of nonribosomal peptide synthetase (NRPS) is responsible for the selective substrate recognition and its activation ( …
26,123 results
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