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Showing results for semax
Your search for asemax retrieved no results
Semax, synthetic ACTH(4-10) analogue, attenuates behavioural and neurochemical alterations following early-life fluvoxamine exposure in white rats.
Glazova NY, Manchenko DM, Volodina MA, Merchieva SA, Andreeva LA, Kudrin VS, Myasoedov NF, Levitskaya NG. Glazova NY, et al. Neuropeptides. 2021 Apr;86:102114. doi: 10.1016/j.npep.2020.102114. Epub 2020 Dec 28. Neuropeptides. 2021. PMID: 33418449
The aim of the present study was to investigate the long-term effects of neonatal exposure to the SSRI fluvoxamine (FA) in white rats. Additionally, the study examined the potential for Semax to prevent the negative consequences of neonatal FA exposure. ...Thus, peptide …
The aim of the present study was to investigate the long-term effects of neonatal exposure to the SSRI fluvoxamine (FA) in white rats. Addit …
Semax, a Synthetic Regulatory Peptide, Affects Copper-Induced Abeta Aggregation and Amyloid Formation in Artificial Membrane Models.
Sciacca MFM, Naletova I, Giuffrida ML, Attanasio F. Sciacca MFM, et al. ACS Chem Neurosci. 2022 Feb 16;13(4):486-496. doi: 10.1021/acschemneuro.1c00707. Epub 2022 Jan 26. ACS Chem Neurosci. 2022. PMID: 35080861 Free PMC article.
Here we tested the anti-aggregating properties of a heptapeptide, Semax, an ACTH-like peptide, which is known to form a stable complex with Cu(2+) ions and has been proven to have neuroprotective and nootropic effects. ...The results suggest that Semax inhibits fibe …
Here we tested the anti-aggregating properties of a heptapeptide, Semax, an ACTH-like peptide, which is known to form a stable comple …
Semax, an analogue of adrenocorticotropin (4-10), binds specifically and increases levels of brain-derived neurotrophic factor protein in rat basal forebrain.
Dolotov OV, Karpenko EA, Seredenina TS, Inozemtseva LS, Levitskaya NG, Zolotarev YA, Kamensky AA, Grivennikov IA, Engele J, Myasoedov NF. Dolotov OV, et al. J Neurochem. 2006 Apr;97 Suppl 1:82-6. doi: 10.1111/j.1471-4159.2006.03658.x. J Neurochem. 2006. PMID: 16635254 Free article.
In addition, we examined whether cell membranes isolated from this brain region contained binding sites for Semax. The binding of tritium-labelled Semax was found to be time dependent, specific and reversible. ...These results point to the presence of specific bindi …
In addition, we examined whether cell membranes isolated from this brain region contained binding sites for Semax. The binding of tri …
Semax, an analog of ACTH((4-7)), regulates expression of immune response genes during ischemic brain injury in rats.
Medvedeva EV, Dmitrieva VG, Limborska SA, Myasoedov NF, Dergunova LV. Medvedeva EV, et al. Mol Genet Genomics. 2017 Jun;292(3):635-653. doi: 10.1007/s00438-017-1297-1. Epub 2017 Mar 2. Mol Genet Genomics. 2017. PMID: 28255762
Semax significantly increased expression of the gene encoding the immunoglobulin heavy chain, highly affects on cytokine, stress response and ribosomal protein-encoding genes after occlusion. ...Our results provided the basis for further proteomic investigations in the fie …
Semax significantly increased expression of the gene encoding the immunoglobulin heavy chain, highly affects on cytokine, stress resp …
[The efficacy of semax in the tretament of patients at different stages of ischemic stroke].
Gusev EI, Martynov MY, Kostenko EV, Petrova LV, Bobyreva SN. Gusev EI, et al. Zh Nevrol Psikhiatr Im S S Korsakova. 2018;118(3. Vyp. 2):61-68. doi: 10.17116/jnevro20181183261-68. Zh Nevrol Psikhiatr Im S S Korsakova. 2018. PMID: 29798983 Clinical Trial. Russian.
All patients were divided into early (899 days) and late (21422 days) rehabilitation groups. Each group was subdivided into semax+ and semax- subgroups. Standard regimen of semax included 2 courses (6000 mcg/day) for 10 days with 20 day interval. ...In sem …
All patients were divided into early (899 days) and late (21422 days) rehabilitation groups. Each group was subdivided into semax+ an …
Effects of Semax on the Default Mode Network of the Brain.
Lebedeva IS, Panikratova YR, Sokolov OY, Kupriyanov DA, Rumshiskaya AD, Kost NV, Myasoedov NF. Lebedeva IS, et al. Bull Exp Biol Med. 2018 Sep;165(5):653-656. doi: 10.1007/s10517-018-4234-3. Epub 2018 Sep 17. Bull Exp Biol Med. 2018. PMID: 30225715
The effects of nootropic drug Semax on the neuronal network of the brain were studied by the resting state functional magnetic-resonance imaging (resting state fMRI). ...A greater volume of the default mode network rostral (medial frontal cortex) subcomponent was detected …
The effects of nootropic drug Semax on the neuronal network of the brain were studied by the resting state functional magnetic-resona …
Semax and Pro-Gly-Pro activate the transcription of neurotrophins and their receptor genes after cerebral ischemia.
Dmitrieva VG, Povarova OV, Skvortsova VI, Limborska SA, Myasoedov NF, Dergunova LV. Dmitrieva VG, et al. Cell Mol Neurobiol. 2010 Jan;30(1):71-9. doi: 10.1007/s10571-009-9432-0. Epub 2009 Jul 25. Cell Mol Neurobiol. 2010. PMID: 19633950
Consisting of a fragment of ACTH(4-7) and C-terminal PGP tripeptide, the polypeptide Semax is successfully used for acute stroke therapy. Previous experiments showed rapid induction of Bdnf, Ngf, and TrkB expression in intact rat hippocampus following Semax treatmen …
Consisting of a fragment of ACTH(4-7) and C-terminal PGP tripeptide, the polypeptide Semax is successfully used for acute stroke ther …
The peptide semax affects the expression of genes related to the immune and vascular systems in rat brain focal ischemia: genome-wide transcriptional analysis.
Medvedeva EV, Dmitrieva VG, Povarova OV, Limborska SA, Skvortsova VI, Myasoedov NF, Dergunova LV. Medvedeva EV, et al. BMC Genomics. 2014 Mar 24;15:228. doi: 10.1186/1471-2164-15-228. BMC Genomics. 2014. PMID: 24661604 Free PMC article.
The peptide predominantly enhanced the expression of genes related to the immune system. Three hours after pMCAO, Semax influenced the expression of some genes that affect the activity of immune cells, and, 24 h after pMCAO, the action of Semax on the immune respons …
The peptide predominantly enhanced the expression of genes related to the immune system. Three hours after pMCAO, Semax influenced th …
Functional Connectomic Approach to Studying Selank and Semax Effects.
Panikratova YR, Lebedeva IS, Sokolov OY, Rumshiskaya AD, Kupriyanov DA, Kost NV, Myasoedov NF. Panikratova YR, et al. Dokl Biol Sci. 2020 Jan;490(1):9-11. doi: 10.1134/S001249662001007X. Epub 2020 Apr 27. Dokl Biol Sci. 2020. PMID: 32342318
The present study was aimed at the assessment of effects of anxiolytic Selank and nootropic Semax on the whole-brain resting-state functional connectivity (FC) of each of the predefined regions of interest (ROIs) in 52 healthy participants. ...Post hoc analysis allowed us …
The present study was aimed at the assessment of effects of anxiolytic Selank and nootropic Semax on the whole-brain resting-state fu …
Semax prevents learning and memory inhibition by heavy metals.
Inozemtsev AN, Bokieva SB, Karpukhina OV, Gumargalieva KZ, Kamensky AA, Myasoedov NF. Inozemtsev AN, et al. Dokl Biol Sci. 2016 May;468(1):112-4. doi: 10.1134/S0012496616030066. Epub 2016 Jul 14. Dokl Biol Sci. 2016. PMID: 27411820
Separate and joint effect of Semax, ascorbic acid, lead diacetate, and ammonium molybdate on avoidance conditioning in rats was studied. It was established that the heavy metal salts inhibited the avoidance response, and the peptide counteracted this inhibition as strongly …
Separate and joint effect of Semax, ascorbic acid, lead diacetate, and ammonium molybdate on avoidance conditioning in rats was studi …
214 results