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Page 1
Brillouin Spectroscopy in Ophthalmology.
Seiler TG, Geerling G. Seiler TG, et al. Klin Monbl Augenheilkd. 2023 Jun;240(6):779-782. doi: 10.1055/a-2085-5738. Epub 2023 May 4. Klin Monbl Augenheilkd. 2023. PMID: 37142238 Review. English, German.
BACKGROUND: Information about corneal biomechanics is crucial for achieving satisfactory outcomes after surgical corneal interventions, e.g., for astigmatic keratotomies, but also to identify corneas that are at risk for postoperative complications such as cornea …
BACKGROUND: Information about corneal biomechanics is crucial for achieving satisfactory outcomes after surgical corneal inter …
Brillouin microscopic depth-dependent analysis of corneal crosslinking performed over or under the LASIK flap.
Zhang H, Roozbahani M, Piccinini AL, Hafezi F, Scarcelli G, Randleman JB. Zhang H, et al. J Cataract Refract Surg. 2020 Nov;46(11):1543-1547. doi: 10.1097/j.jcrs.0000000000000294. J Cataract Refract Surg. 2020. PMID: 33149067 Free PMC article.
PURPOSE: To determine the impact of corneal crosslinking (CXL) performed over the laser in situ keratomileusis (LASIK) flap using the Standard CXL (S-CXL) protocol or under the flap after flap lift (flap-CXL) on regional corneal stiffness using Brillouin micr …
PURPOSE: To determine the impact of corneal crosslinking (CXL) performed over the laser in situ keratomileusis (LASIK) flap using the …
Detecting Mechanical Anisotropy of the Cornea Using Brillouin Microscopy.
Webb JN, Zhang H, Sinha Roy A, Randleman JB, Scarcelli G. Webb JN, et al. Transl Vis Sci Technol. 2020 Jun 24;9(7):26. doi: 10.1167/tvst.9.7.26. eCollection 2020 Jun. Transl Vis Sci Technol. 2020. PMID: 32832232 Free PMC article.
We experimentally measured and theoretically modeled how mechanical changes independent of hydration affect frequency shift as a result of corneal cross-linking by isolating an approximately 100 MHz increase in frequency shift following a cross-link …
We experimentally measured and theoretically modeled how mechanical changes independent of hydration affect frequency shift as a result of …
A review of imaging modalities for detecting early keratoconus.
Zhang X, Munir SZ, Sami Karim SA, Munir WM. Zhang X, et al. Eye (Lond). 2021 Jan;35(1):173-187. doi: 10.1038/s41433-020-1039-1. Epub 2020 Jul 16. Eye (Lond). 2021. PMID: 32678352 Free PMC article. Review.
OBJECTIVES: Early identification of keratoconus is imperative for preventing iatrogenic corneal ectasia and allowing for early corneal collagen cross-linking treatments to potentially halt progression and decrease transplant burden. ...RESULTS: A combi …
OBJECTIVES: Early identification of keratoconus is imperative for preventing iatrogenic corneal ectasia and allowing for early cor …
Depth-Dependent Reduction of Biomechanical Efficacy of Contact Lens-Assisted Corneal Cross-linking Analyzed by Brillouin Microscopy.
Zhang H, Roozbahani M, Piccinini AL, Golan O, Hafezi F, Scarcelli G, Randleman JB. Zhang H, et al. J Refract Surg. 2019 Nov 1;35(11):721-728. doi: 10.3928/1081597X-20191004-01. J Refract Surg. 2019. PMID: 31710374 Free PMC article.
PURPOSE: To determine the relative impact of contact lens- assisted corneal cross-linking (CACXL) and standard protocol CXL (CXL) on regional corneal stiffness using Brillouin microscopy. ...Depth profile of stiffness variation and averaged elas …
PURPOSE: To determine the relative impact of contact lens- assisted corneal cross-linking (CACXL) and standard protocol …
Biomechanical Impact of Localized Corneal Cross-linking Beyond the Irradiated Treatment Area.
Webb JN, Langille E, Hafezi F, Randleman JB, Scarcelli G. Webb JN, et al. J Refract Surg. 2019 Apr 1;35(4):253-260. doi: 10.3928/1081597X-20190304-01. J Refract Surg. 2019. PMID: 30984983 Free PMC article.
PURPOSE: To investigate the stiffening effect of localized corneal cross-linking (L-CXL) within and beyond the irradiated region in three dimensions. ...The three-dimensional biomechanical properties of each cornea were then measured via Brillouin micr …
PURPOSE: To investigate the stiffening effect of localized corneal cross-linking (L-CXL) within and beyond the irradiat …
Brillouin microscopy: assessing ocular tissue biomechanics.
Yun SH, Chernyak D. Yun SH, et al. Curr Opin Ophthalmol. 2018 Jul;29(4):299-305. doi: 10.1097/ICU.0000000000000489. Curr Opin Ophthalmol. 2018. PMID: 29771749 Free PMC article. Review.
However, it has been difficult to accurately characterize corneal biomechanics in patients. The recent development of Brillouin light scattering microscopy heightens the promise of bringing biomechanics into the clinic. ...Human clinical studies have demonstrated si …
However, it has been difficult to accurately characterize corneal biomechanics in patients. The recent development of Brillouin …
Mechanical outcome of accelerated corneal crosslinking evaluated by Brillouin microscopy.
Webb JN, Su JP, Scarcelli G. Webb JN, et al. J Cataract Refract Surg. 2017 Nov;43(11):1458-1463. doi: 10.1016/j.jcrs.2017.07.037. J Cataract Refract Surg. 2017. PMID: 29223236 Free PMC article.
PURPOSE: To quantify corneal mechanical changes induced by corneal crosslinking (CXL) procedures of different ultraviolet-A (UVA) intensity and exposure time using Brillouin microscopy. ...RESULTS: The standard 3 mW/cm(2) irradiance condition produced a signi …
PURPOSE: To quantify corneal mechanical changes induced by corneal crosslinking (CXL) procedures of different ultraviolet-A (U …
Biomechanical Diagnostics of the Cornea.
De Stefano VS, Dupps WJ Jr. De Stefano VS, et al. Int Ophthalmol Clin. 2017 Summer;57(3):75-86. doi: 10.1097/IIO.0000000000000172. Int Ophthalmol Clin. 2017. PMID: 28590282 Free PMC article. Review.
A better understanding of its biomechanical features is essential to understand the consequences of procedures such excimer laser refractive surgery and corneal collagen crosslinking and to improve the detection and management of ectatic corneal diseases. ...To addr …
A better understanding of its biomechanical features is essential to understand the consequences of procedures such excimer laser refractive …
Biomechanical Changes After LASIK Flap Creation Combined With Rapid Cross-Linking Measured With Brillouin Microscopy.
Randleman JB, Su JP, Scarcelli G. Randleman JB, et al. J Refract Surg. 2017 Jun 1;33(6):408-414. doi: 10.3928/1081597X-20170421-01. J Refract Surg. 2017. PMID: 28586502
PURPOSE: To evaluate the biomechanical changes occurring after LASIK flap creation and rapid corneal cross-linking (CXL) measured with Brillouin light microscopy. ...Rapid corneal cross-linking had no significant effect on Brill …
PURPOSE: To evaluate the biomechanical changes occurring after LASIK flap creation and rapid corneal cross-linking (CXL …
13 results