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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1851 1
1860 1
1861 1
1868 1
1873 1
1881 1
1885 3
1886 1
1888 1
1889 1
1890 1
1891 1
1894 2
1895 1
1907 1
1910 2
1911 1
1912 2
1913 1
1917 1
1918 1
1920 1
1923 1
1924 1
1925 2
1926 1
1928 1
1930 1
1931 1
1939 1
1941 1
1943 1
1944 1
1945 13
1946 20
1947 13
1948 13
1949 17
1950 22
1951 35
1952 39
1953 66
1954 64
1955 45
1956 52
1957 57
1958 38
1959 48
1960 42
1961 41
1962 74
1963 123
1964 177
1965 125
1966 122
1967 169
1968 211
1969 238
1970 279
1971 269
1972 301
1973 310
1974 329
1975 339
1976 341
1977 292
1978 296
1979 312
1980 321
1981 335
1982 370
1983 391
1984 486
1985 495
1986 527
1987 500
1988 523
1989 616
1990 623
1991 643
1992 645
1993 610
1994 681
1995 665
1996 679
1997 677
1998 657
1999 711
2000 762
2001 752
2002 761
2003 737
2004 784
2005 823
2006 907
2007 875
2008 884
2009 869
2010 974
2011 992
2012 1079
2013 1142
2014 1216
2015 1221
2016 1293
2017 1263
2018 1404
2019 1400
2020 1455
2021 1537
2022 1535
2023 1489
2024 635

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39,508 results

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Page 1
Caffeine: cognitive and physical performance enhancer or psychoactive drug?
Cappelletti S, Piacentino D, Sani G, Aromatario M. Cappelletti S, et al. Curr Neuropharmacol. 2015 Jan;13(1):71-88. doi: 10.2174/1570159X13666141210215655. Curr Neuropharmacol. 2015. PMID: 26074744 Free PMC article. Review.
The present review summarizes the main findings concerning caffeine's mechanisms of action (focusing on adenosine antagonism, intracellular calcium mobilization, and phosphodiesterases inhibition), use, abuse, dependence, intoxication, and lethal effects. It also su …
The present review summarizes the main findings concerning caffeine's mechanisms of action (focusing on adenosine antagonism, …
Caffeine, coffee, and appetite control: a review.
Schubert MM, Irwin C, Seay RF, Clarke HE, Allegro D, Desbrow B. Schubert MM, et al. Int J Food Sci Nutr. 2017 Dec;68(8):901-912. doi: 10.1080/09637486.2017.1320537. Epub 2017 Apr 27. Int J Food Sci Nutr. 2017. PMID: 28446037 Review.
The purpose of this review was to examine the evidence regarding coffee and caffeine's influence on energy intake and appetite control. The literature was examined for studies that assessed the effects of caffeine and coffee on energy intake, gastric emptying …
The purpose of this review was to examine the evidence regarding coffee and caffeine's influence on energy intake and appetite …
Caffeine and Exercise: What Next?
Pickering C, Grgic J. Pickering C, et al. Sports Med. 2019 Jul;49(7):1007-1030. doi: 10.1007/s40279-019-01101-0. Sports Med. 2019. PMID: 30977054 Free PMC article. Review.
In recent years, a number of meta-analyses have demonstrated that caffeine's ergogenic effects on exercise performance are well-established and well-replicated, appearing consistent across a broad range of exercise modalities. ...We propose that future research shou …
In recent years, a number of meta-analyses have demonstrated that caffeine's ergogenic effects on exercise performance are wel …
Caffeine's mechanisms of action and its cosmetic use.
Herman A, Herman AP. Herman A, et al. Skin Pharmacol Physiol. 2013;26(1):8-14. doi: 10.1159/000343174. Epub 2012 Oct 11. Skin Pharmacol Physiol. 2013. PMID: 23075568 Review.
Caffeine is being increasingly used in cosmetics due to its high biological activity and ability to penetrate the skin barrier. This alkaloid is frequently used as a hydrophilic model substance in human and animal skin penetration as well as different synthetic membrane us …
Caffeine is being increasingly used in cosmetics due to its high biological activity and ability to penetrate the skin barrier. This …
Caffeine in the Diet: Country-Level Consumption and Guidelines.
Reyes CM, Cornelis MC. Reyes CM, et al. Nutrients. 2018 Nov 15;10(11):1772. doi: 10.3390/nu10111772. Nutrients. 2018. PMID: 30445721 Free PMC article. Review.
Coffee, tea, caffeinated soda, and energy drinks are important sources of caffeine in the diet but each present with other unique nutritional properties. ...Using the Food and Agriculture Organization list of 90 countries with FBDG as a starting point, we found refe …
Coffee, tea, caffeinated soda, and energy drinks are important sources of caffeine in the diet but each present with other uni …
Effect of Caffeine Consumption on the Risk for Neurological and Psychiatric Disorders: Sex Differences in Human.
Jee HJ, Lee SG, Bormate KJ, Jung YS. Jee HJ, et al. Nutrients. 2020 Oct 9;12(10):3080. doi: 10.3390/nu12103080. Nutrients. 2020. PMID: 33050315 Free PMC article. Review.
However, excessive caffeine consumption (1~1.5 g/day) can cause caffeine poisoning (caffeinism), which includes symptoms such as anxiety, agitation, insomnia, and gastrointestinal disorders. ...The findings may help establish new strategies for developing sex …
However, excessive caffeine consumption (1~1.5 g/day) can cause caffeine poisoning (caffeinism), which includes symptom …
Administration of Caffeine in Alternate Forms.
Wickham KA, Spriet LL. Wickham KA, et al. Sports Med. 2018 Mar;48(Suppl 1):79-91. doi: 10.1007/s40279-017-0848-2. Sports Med. 2018. PMID: 29368182 Free PMC article. Review.
Caffeinated chewing gum is absorbed quicker through the buccal mucosa compared with capsule delivery and absorption in the gut, although total caffeine absorption over time is not different. ...Studies with caffeinated energy drinks have generally not examine …
Caffeinated chewing gum is absorbed quicker through the buccal mucosa compared with capsule delivery and absorption in the gut, altho …
The neuroprotective effects of caffeine in neurodegenerative diseases.
Kolahdouzan M, Hamadeh MJ. Kolahdouzan M, et al. CNS Neurosci Ther. 2017 Apr;23(4):272-290. doi: 10.1111/cns.12684. CNS Neurosci Ther. 2017. PMID: 28317317 Free PMC article. Review.
Similar effects of caffeine were observed in men with Parkinson's disease (PD); however, the effect of caffeine in female PD patients is controversial due to caffeine's competition with estrogen for the estrogen-metabolizing enzyme, CYP1A2. ...Caffe …
Similar effects of caffeine were observed in men with Parkinson's disease (PD); however, the effect of caffeine in female PD p …
[Caffeine: a nutrient, a drug or a drug of abuse].
Pardo Lozano R, Alvarez García Y, Barral Tafalla D, Farré Albaladejo M. Pardo Lozano R, et al. Adicciones. 2007;19(3):225-38. Adicciones. 2007. PMID: 17724925 Free article. Review. Spanish.
Coffee, tea, chocolate and caffeinated drinks are the main sources of caffeine, which is consumed in almost all ages and socioeconomic levels. Caffeine acts as a non-selective adenosine receptor antagonist in the central nervous system. ...
Coffee, tea, chocolate and caffeinated drinks are the main sources of caffeine, which is consumed in almost all ages and socio …
Mental Performance and Sport: Caffeine and Co-consumed Bioactive Ingredients.
Kennedy DO, Wightman EL. Kennedy DO, et al. Sports Med. 2022 Dec;52(Suppl 1):69-90. doi: 10.1007/s40279-022-01796-8. Epub 2022 Nov 30. Sports Med. 2022. PMID: 36447122 Free PMC article. Review.
It has no consistent effect within other cognitive domains that are important to sporting performance, including working memory, executive function and long-term memory. Although caffeine's central nervous system effects are often attributed to blockade of the recep …
It has no consistent effect within other cognitive domains that are important to sporting performance, including working memory, executive f …
39,508 results
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