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Clinicians' Guide to Cannabidiol and Hemp Oils.

VanDolah HJ, Bauer BA, Mauck KF. VanDolah HJ, et al. Mayo Clin Proc. 2019 Sep;94(9):1840-1851. doi: 10.1016/j.mayocp.2019.01.003. Epub 2019 Aug 22. Mayo Clin Proc. 2019. PMID: 31447137 Free article. Review.

This article provides an overview of the scientific work on cannabinoids, CBD, and hemp oil and the distinction between marijuana, hemp, and the different components of CBD and hemp oil products. ...This review is based on a PubMed search using the ter …

This article provides an overview of the scientific work on cannabinoids, CBD, and hemp oil and the distinction between mariju …

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2

Short-Term Efficacy of CBD-Enriched Hemp Oil in Girls with Dysautonomic Syndrome after Human Papillomavirus Vaccination.

Palmieri B, Laurino C, Vadalà M. Palmieri B, et al. Isr Med Assoc J. 2017 Feb;19(2):79-84. Isr Med Assoc J. 2017. PMID: 28457055 Free article. Clinical Trial.

OBJECTIVES: To investigate the short-term effect of CBD-enriched hemp oil for relieving symptoms and improving the life quality (QOL) in young girls with adverse drug effects (ADRs) following human papillomavirus (HPV) vaccine. METHODS: In this anecdotal, retrospect …

OBJECTIVES: To investigate the short-term effect of CBD-enriched hemp oil for relieving symptoms and improving the life qualit …

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3

CBD-enriched medical cannabis for intractable pediatric epilepsy: The current Israeli experience.

Tzadok M, Uliel-Siboni S, Linder I, Kramer U, Epstein O, Menascu S, Nissenkorn A, Yosef OB, Hyman E, Granot D, Dor M, Lerman-Sagie T, Ben-Zeev B. Tzadok M, et al. Seizure. 2016 Feb;35:41-4. doi: 10.1016/j.seizure.2016.01.004. Epub 2016 Jan 6. Seizure. 2016. PMID: 26800377 Free article.

They all started medical cannabis oil treatment between 2-11/2014 and were treated for at least 3 months (average 6 months). The selected formula contained CBD and tetrahydrocannabinol at a ratio of 20:1 dissolved in olive oil. The CBD dose ranged from …

They all started medical cannabis oil treatment between 2-11/2014 and were treated for at least 3 months (average 6 months). The sele …

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4

A selective review of medical cannabis in cancer pain management.

Blake A, Wan BA, Malek L, DeAngelis C, Diaz P, Lao N, Chow E, O'Hearn S. Blake A, et al. Ann Palliat Med. 2017 Dec;6(Suppl 2):S215-S222. doi: 10.21037/apm.2017.08.05. Epub 2017 Aug 23. Ann Palliat Med. 2017. PMID: 28866904 Free article. Review.

Five studies that evaluated THC oil capsules, THC:CBD oromucosal spray (nabiximols), or THC oromucosal sprays found some evidence of cancer pain reduction associated with these therapies. A variety of doses ranging from 2.7-43.2 mg/day THC and 0-40 mg/day CBD …

Five studies that evaluated THC oil capsules, THC:CBD oromucosal spray (nabiximols), or THC oromucosal sprays found some evide …

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5

A prospective open-label trial of a CBD/THC cannabis oil in dravet syndrome.

McCoy B, Wang L, Zak M, Al-Mehmadi S, Kabir N, Alhadid K, McDonald K, Zhang G, Sharma R, Whitney R, Sinopoli K, Snead OC 3rd. McCoy B, et al. Ann Clin Transl Neurol. 2018 Aug 1;5(9):1077-1088. doi: 10.1002/acn3.621. eCollection 2018 Sep. Ann Clin Transl Neurol. 2018. PMID: 30250864 Free PMC article.

INTRODUCTION: Both Δ(9) Tetrahydrocannabidiol (THC) and cannabidiol (CBD) components of cannabis, have been shown to have anticonvulsant effects. ...Recent trials provide data on dosing, side effects, and efficacy of CBD, yet there is a paucity of information on THC …

INTRODUCTION: Both Δ(9) Tetrahydrocannabidiol (THC) and cannabidiol (CBD) components of cannabis, have been shown to have anticonvuls …

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6

Cannabidiol Oil for Decreasing Addictive Use of Marijuana: A Case Report.

Shannon S, Opila-Lehman J. Shannon S, et al. Integr Med (Encinitas). 2015 Dec;14(6):31-5. Integr Med (Encinitas). 2015. PMID: 26807069 Free PMC article.

This case study illustrates the use of cannabidiol (CBD) oil to decrease the addictive use of marijuana and provide anxiolytic and sleep benefits. ...With use of the CBD oil, the patient reported being less anxious, as well as settling into a regular p …

This case study illustrates the use of cannabidiol (CBD) oil to decrease the addictive use of marijuana and provide anxiolytic …

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7

Cannabidiol: promise and pitfalls.

Welty TE, Luebke A, Gidal BE. Welty TE, et al. Epilepsy Curr. 2014 Sep;14(5):250-2. doi: 10.5698/1535-7597-14.5.250. Epilepsy Curr. 2014. PMID: 25346628 Free PMC article.

Despite initiatives in numerous states to at least legalize possession of CBD oil for treating epilepsy, little published evidence is available to prove or disprove the efficacy and safety of CBD in patients with epilepsy. This review highlights some of the b …

Despite initiatives in numerous states to at least legalize possession of CBD oil for treating epilepsy, little published evid …

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8

Evaluation of cannabinoids concentration and stability in standardized preparations of cannabis tea and cannabis oil by ultra-high performance liquid chromatography tandem mass spectrometry.

Pacifici R, Marchei E, Salvatore F, Guandalini L, Busardò FP, Pichini S. Pacifici R, et al. Clin Chem Lab Med. 2017 Aug 28;55(10):1555-1563. doi: 10.1515/cclm-2016-1060. Clin Chem Lab Med. 2017. PMID: 28207408

The combination of the psychoactive cannabis alkaloid Δ9-tetrahydrocannabinol (THC) with the non-psychotropic alkaloids cannabidiol (CBD) and cannabinol (CBN) demonstrated a higher activity than THC alone. ...At ambient temperature, a significant THC and CBD decreas …

The combination of the psychoactive cannabis alkaloid Δ9-tetrahydrocannabinol (THC) with the non-psychotropic alkaloids cannabidiol (CBD …

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9

Cannabidiol: The Need for More Information About Its Potential Benefits and Side Effects.

Hande K. Hande K. Clin J Oncol Nurs. 2019 Apr 1;23(2):131-134. doi: 10.1188/19.CJON.131-134. Clin J Oncol Nurs. 2019. PMID: 30880812

Consumer demand for cannabidiol (CBD) oil has increased, with growing sales from dispensaries because of the alleged medicinal benefits. Although studies examining the specific therapeutic effects of CBD are increasing, clinical data do not support the popula …

Consumer demand for cannabidiol (CBD) oil has increased, with growing sales from dispensaries because of the alleged medicinal …

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10

Dramatic response to Laetrile and cannabidiol (CBD) oil in a patient with metastatic low grade serous ovarian carcinoma.

Barrie AM, Gushue AC, Eskander RN. Barrie AM, et al. Gynecol Oncol Rep. 2019 May 17;29:10-12. doi: 10.1016/j.gore.2019.05.004. eCollection 2019 Aug. Gynecol Oncol Rep. 2019. PMID: 31193514 Free PMC article.

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