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1984 1
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1994 23
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1999 100
2000 84
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2004 126
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2006 144
2007 132
2008 133
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Page 1
Effect of Cefepime/Enmetazobactam vs Piperacillin/Tazobactam on Clinical Cure and Microbiological Eradication in Patients With Complicated Urinary Tract Infection or Acute Pyelonephritis: A Randomized Clinical Trial.
Kaye KS, Belley A, Barth P, Lahlou O, Knechtle P, Motta P, Velicitat P. Kaye KS, et al. JAMA. 2022 Oct 4;328(13):1304-1314. doi: 10.1001/jama.2022.17034. JAMA. 2022. PMID: 36194218 Free PMC article. Clinical Trial.
IMPORTANCE: Cefepime/enmetazobactam is a novel beta-lactam/beta-lactamase inhibitor combination and a potential empirical therapy for resistant gram-negative infections. ...Further research is needed to determine the potential role for cefepime/enmetazobactam in the …
IMPORTANCE: Cefepime/enmetazobactam is a novel beta-lactam/beta-lactamase inhibitor combination and a potential empirical therapy for …
Clinical Pharmacokinetics and Pharmacodynamics of Cefepime.
Pais GM, Chang J, Barreto EF, Stitt G, Downes KJ, Alshaer MH, Lesnicki E, Panchal V, Bruzzone M, Bumanglag AV, Burke SN, Scheetz MH. Pais GM, et al. Clin Pharmacokinet. 2022 Jul;61(7):929-953. doi: 10.1007/s40262-022-01137-y. Epub 2022 Jun 29. Clin Pharmacokinet. 2022. PMID: 35764774 Free PMC article. Review.
Cefepime is a broad-spectrum fourth-generation cephalosporin with activity against Gram-positive and Gram-negative pathogens. ...This review summarizes the pharmacokinetics, pharmacodynamics, and toxicodynamics of cefepime contemporarily in the setting of increasing …
Cefepime is a broad-spectrum fourth-generation cephalosporin with activity against Gram-positive and Gram-negative pathogens. ...This …
Cefepime-Taniborbactam in Complicated Urinary Tract Infection.
Wagenlehner FM, Gasink LB, McGovern PC, Moeck G, McLeroth P, Dorr M, Dane A, Henkel T; CERTAIN-1 Study Team. Wagenlehner FM, et al. N Engl J Med. 2024 Feb 15;390(7):611-622. doi: 10.1056/NEJMoa2304748. N Engl J Med. 2024. PMID: 38354140 Clinical Trial.
Composite success occurred in 207 of 293 patients (70.6%) in the cefepime-taniborbactam group and in 83 of 143 patients (58.0%) in the meropenem group. ...Differences in treatment response were sustained at late follow-up (trial days 28 to 35), when cefepime-tanibor …
Composite success occurred in 207 of 293 patients (70.6%) in the cefepime-taniborbactam group and in 83 of 143 patients (58.0%) in th …
Cefepime Dosing in Neonates: What is the Evidence?
McDonald D, Shah P. McDonald D, et al. Am J Perinatol. 2021 Jun;38(7):657-661. doi: 10.1055/s-0039-3400312. Epub 2019 Nov 27. Am J Perinatol. 2021. PMID: 31777048 Review.
OBJECTIVE: Recommended cefepime dosing strategies in neonates varies in commonly utilized dosing references with regard to dose and frequency. The objective of this review is to summarize and evaluate the available literature describing cefepime dosing in neonatal p …
OBJECTIVE: Recommended cefepime dosing strategies in neonates varies in commonly utilized dosing references with regard to dose and f …
Cefepime-induced neurotoxicity: systematic review.
Maan G, Keitoku K, Kimura N, Sawada H, Pham A, Yeo J, Hagiya H, Nishimura Y. Maan G, et al. J Antimicrob Chemother. 2022 Oct 28;77(11):2908-2921. doi: 10.1093/jac/dkac271. J Antimicrob Chemother. 2022. PMID: 35971666
BACKGROUND: Cefepime-induced neurotoxicity (CIN) has been well acknowledged among clinicians, although there are no clear diagnostic criteria or specific laboratory testing to help with its diagnosis. ...Among 119 patients with CIN, 23.5% were in the ICU at the time of dia …
BACKGROUND: Cefepime-induced neurotoxicity (CIN) has been well acknowledged among clinicians, although there are no clear diagnostic …
[Cefepime-induced encephalopathy].
Muradbegovic J, Leidi A, Serratrice J. Muradbegovic J, et al. Rev Med Suisse. 2019 Nov 27;15(673):2210-2212. Rev Med Suisse. 2019. PMID: 31778052 Review. French.
Since 2017 the world suffers from a piperacillin/tazobactam shortage. Cefepime is then proposed as a broad spectrum antibiotic alternative. Up to 15 % of the patients under treatment develop neurotoxicity, mostly in kidney failure settings. Cefepime serum concentrat …
Since 2017 the world suffers from a piperacillin/tazobactam shortage. Cefepime is then proposed as a broad spectrum antibiotic altern …
Activity of cefiderocol, imipenem/relebactam, cefepime/taniborbactam and cefepime/zidebactam against ceftolozane/tazobactam- and ceftazidime/avibactam-resistant Pseudomonas aeruginosa.
Lasarte-Monterrubio C, Fraile-Ribot PA, Vázquez-Ucha JC, Cabot G, Guijarro-Sánchez P, Alonso-García I, Rumbo-Feal S, Galán-Sánchez F, Beceiro A, Arca-Suárez J, Oliver A, Bou G. Lasarte-Monterrubio C, et al. J Antimicrob Chemother. 2022 Sep 30;77(10):2809-2815. doi: 10.1093/jac/dkac241. J Antimicrob Chemother. 2022. PMID: 35904000
OBJECTIVES: To evaluate the activity of cefiderocol, imipenem/relebactam, cefepime/taniborbactam and cefepime/zidebactam against a clinical and laboratory collection of ceftolozane/tazobactam- and ceftazidime/avibactam-resistant Pseudomonas aeruginosa beta-lactamase …
OBJECTIVES: To evaluate the activity of cefiderocol, imipenem/relebactam, cefepime/taniborbactam and cefepime/zidebactam again …
Cefepime.
Cunha BA, Gill MV. Cunha BA, et al. Med Clin North Am. 1995 Jul;79(4):721-32. doi: 10.1016/s0025-7125(16)30035-9. Med Clin North Am. 1995. PMID: 7791419 Free article. Review.
The clinical efficacy of cefepime has been demonstrated in comparative and noncomparative trials in the United States and Europe. ...Cefepime is also active against organisms that show resistance to other agents. ...
The clinical efficacy of cefepime has been demonstrated in comparative and noncomparative trials in the United States and Europe. ... …
Prolonged Cefepime-Induced Neurotoxicity in a Patient with End-Stage Renal Disease.
Nguyen DD, Lai S. Nguyen DD, et al. Am J Case Rep. 2022 Jan 24;23:e934083. doi: 10.12659/AJCR.934083. Am J Case Rep. 2022. PMID: 35067669 Free PMC article. Review.
BACKGROUND Cefepime, a fourth-generation cephalosporin, has a known adverse effect of neurotoxicity. ...CONCLUSIONS Careful attention should be paid when administering cefepime to patients with end-stage renal disease. Patients showing signs of encephalopathy should …
BACKGROUND Cefepime, a fourth-generation cephalosporin, has a known adverse effect of neurotoxicity. ...CONCLUSIONS Careful attention …
The Role of Cefepime in the Treatment of Extended-Spectrum Beta-Lactamase Infections.
Patel HB, Lusk KA, Cota JM. Patel HB, et al. J Pharm Pract. 2019 Aug;32(4):458-463. doi: 10.1177/0897190017743134. Epub 2017 Nov 22. J Pharm Pract. 2019. PMID: 29166830 Review.
OBJECTIVE: To review the efficacy of cefepime for use in infections caused by extended-spectrum beta-lactamase (ESBL)-producing organisms. ...The largest pharmacokinetic/pharmacodynamic study, a Monte Carlo simulation using data from the U.S. SENTRY antimicrobial surveilla …
OBJECTIVE: To review the efficacy of cefepime for use in infections caused by extended-spectrum beta-lactamase (ESBL)-producing organ …
4,824 results

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