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[Effects of cortiphen on human tumor strains transplanted into athymic mice and rats].
Bukharova IK, Revazova ES, Moroz LV. Bukharova IK, et al. Eksp Onkol. 1990;12(1):66-8. Eksp Onkol. 1990. PMID: 2298147 Russian.
The antitumour activity of cortiphen synthesized at the All-Union Cancer Research Centre of the USSR Academy of Medical Sciences was studied on human tumour strains transplanted into nude mice and rats. Cortiphen was found to possess an expressed activity to kidney …
The antitumour activity of cortiphen synthesized at the All-Union Cancer Research Centre of the USSR Academy of Medical Sciences was …
[Effects of cortiphen and cyclophosphamide in uterine sarcoma induced primarily by 1,2-dimethylhydrazine and estradiol dipropionate in CBA mice].
Merkulova IB, Vvedenskaia NA, Kiselev VI. Merkulova IB, et al. Eksp Onkol. 1990;12(1):68-70. Eksp Onkol. 1990. PMID: 2298148 Russian.
Cortiphen and cyclophosphamide were studied for their effect on the mixed uterus sarcoma induced primarily by 1,2-dimethylhydrazine and oestradiol-dipropionate in CBA mice and its transplants. ...
Cortiphen and cyclophosphamide were studied for their effect on the mixed uterus sarcoma induced primarily by 1,2-dimethylhydrazine a
[Experimental study of the antitumor properties and mechanism of action of kortifen].
Lagova ND, Kiselev VI, Kurdiumova KN, Sof'ina ZP, Shkodinskaia EN. Lagova ND, et al. Vopr Onkol. 1989;35(4):450-6. Vopr Onkol. 1989. PMID: 2728387 Russian.
Cortiphen, a newly developed hormonal cytostatic ester of 11-desoxy-17 alpha-hydroxycorticosterone and chlorophenacyl, is described. ...Cortiphen was found to interact with glucocorticoid receptors in both animal and human tumors. ...
Cortiphen, a newly developed hormonal cytostatic ester of 11-desoxy-17 alpha-hydroxycorticosterone and chlorophenacyl, is described.
Different Efficiency of Liposomal Forms with Hydrophilic and Hydrophobic Antitumor Agents in Relation to Solid Transplants of Mouse Tumor and Its Metastases in the Liver.
Popova NA, Kaledin VI, Nikolin VP, Bogdanova LA, Morozkova TS, Tornuev YV. Popova NA, et al. Bull Exp Biol Med. 2016 Oct;161(6):811-815. doi: 10.1007/s10517-016-3518-8. Epub 2016 Oct 26. Bull Exp Biol Med. 2016. PMID: 27783294
By contrast, liposomal cycloplatam had lower efficiency than free cycloplatam in suppressing the growth of solid tumor. Liposomal and free cortifen (hydrophobic hormonal cytostatic) produced nearly the same effects on solid tumor growth. ...
By contrast, liposomal cycloplatam had lower efficiency than free cycloplatam in suppressing the growth of solid tumor. Liposomal and free …
[The action of cortifen and corticosterone on the thymocyte nucleoid of mice in vivo and in vitro].
Struchkov VA, Suslova OA. Struchkov VA, et al. Farmakol Toksikol. 1988 Nov-Dec;51(6):76-80. Farmakol Toksikol. 1988. PMID: 3234545 Russian.
The effect of therapeutic doses of a hormonal cytostatic cortifen and corticosterone on supramolecular DNA structures of mice thymocyte nucleoid was studied. ...After 24 hours the damaging effects on nucleoid were markedly higher. The role of the hormone and alkylating gro …
The effect of therapeutic doses of a hormonal cytostatic cortifen and corticosterone on supramolecular DNA structures of mice thymocy …
[The immunodepressive and lympholytic action of kortifen].
Pykhtina AA, Gladkova NE. Pykhtina AA, et al. Farmakol Toksikol. 1988 Sep-Oct;51(5):72-4. Farmakol Toksikol. 1988. PMID: 3208888 Russian.
The study of the effect of a new antitumor drug cortifen on humoral immunity in experiments on CBA mice showed that it is a potent and long acting immunodepressant. The degree of immunity depression was found to be drug dose-dependent. The hormonal components of cortife
The study of the effect of a new antitumor drug cortifen on humoral immunity in experiments on CBA mice showed that it is a potent an …