Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2006 1
2008 3
2010 2
2011 2
2012 10
2013 6
2014 6
2015 4
2016 9
2017 6
2018 7
2019 7
2020 10
2021 16
2022 17
2023 21
2024 14
2025 11

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

136 results

Results by year

Filters applied: . Clear all
Page 1
Importance of Lysosomal Trapping and Plasmodium Parasite Infection on the Pharmacokinetics of Pyronaridine: A Physiologically Based Pharmacokinetic Model-Based Study.
Chu WY, Schouten WM, Mavoko HM, Tshiongo JK, Yobi DM, Kabasele FA, Kasereka G, Maketa V, Sevene E, Vala A, Shin J, D'Alessandro U, Kayentao K, Huitema ADR, Dorlo TPC. Chu WY, et al. Clin Pharmacokinet. 2025 Sep 30. doi: 10.1007/s40262-025-01581-6. Online ahead of print. Clin Pharmacokinet. 2025. PMID: 41026410
Pharmacokinetics and Pharmacodynamics of Fosravuconazole, Itraconazole, and Hydroxyitraconazole in Sudanese Patients With Eumycetoma.
Chu WY, Fahal AH, Ahmed ES, Bakhiet SM, Bakhiet OE, Fahal LA, Mohamed AA, Mohamedelamin ESW, Bahar MEN, Attalla HY, Siddig EE, Mhmoud NA, Musa AM, Oyieko P, Egondi T, Brüggemann RJ, Hata K, Strub-Wourgaft N, Alves F, Nyaoke BA, Zijlstra EE, Dorlo TPC. Chu WY, et al. J Infect Dis. 2025 Sep 15;232(3):e518-e528. doi: 10.1093/infdis/jiaf279. J Infect Dis. 2025. PMID: 40433693 Free PMC article. Clinical Trial.
Simplifying medicine dosing for children by harmonising weight bands across therapeutic areas.
Waalewijn H, Almett M, Wasmann RE, Cressey TR, Easterbrook P, Olumese PE, Hesseling AC, Garcia-Prats AJ, Tarning J, Turkova A, Viney K, Svensson EM, Colbers A, Were WM, Denti P, Penazzato M; members of the expert panels. Waalewijn H, et al. Lancet Child Adolesc Health. 2025 Apr;9(4):274-282. doi: 10.1016/S2352-4642(25)00025-2. Lancet Child Adolesc Health. 2025. PMID: 40113369 Review.
Pharmacokinetic Model-Informed Precision Dosing of Natalizumab in Multiple Sclerosis.
van den Berg SPH, Toorop AA, Hooijberg F, Wolbink G, Voelkner NMF, Gelissen LMY, Killestein J, van Kempen ZLE, Dorlo TPC, Rispens T. van den Berg SPH, et al. CPT Pharmacometrics Syst Pharmacol. 2025 Jun;14(6):1032-1041. doi: 10.1002/psp4.70014. Epub 2025 Mar 20. CPT Pharmacometrics Syst Pharmacol. 2025. PMID: 40110747 Free PMC article.
Development and validation of ultra-performance liquid chromatography tandem mass spectrometry methods for the quantitative analysis of the antiparasitic drug DNDI-6148 in human plasma and various mouse biomatrices.
Schouten WM, Van Bocxlaer K, Rosing H, Huitema ADR, Beijnen JH, Kratz JM, Mowbray CE, Dorlo TPC. Schouten WM, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2025 Jan 1;1250:124377. doi: 10.1016/j.jchromb.2024.124377. Epub 2024 Nov 12. J Chromatogr B Analyt Technol Biomed Life Sci. 2025. PMID: 39577310 Free article.
Disease-Specific Differences in Pharmacokinetics of Paromomycin and Miltefosine Between Post-Kala-Azar Dermal Leishmaniasis and Visceral Leishmaniasis Patients in Eastern Africa.
Chu WY, Verrest L, Younis BM, Musa AM, Mbui J, Mohammed R, Olobo J, Ritmeijer K, Monnerat S, Wasunna M, Roseboom IC, Solomos A, Huitema ADR, Alves F, Dorlo TPC. Chu WY, et al. J Infect Dis. 2024 Dec 16;230(6):e1375-e1384. doi: 10.1093/infdis/jiae413. J Infect Dis. 2024. PMID: 39166299 Free PMC article.
Population Pharmacokinetics and Target Attainment of Allopurinol and Oxypurinol Before, During, and After Cardiac Surgery with Cardiopulmonary Bypass in Neonates with Critical Congenital Heart Disease.
Chu WY, Nijman M, Stegeman R, Breur JMPJ, Jansen NJG, Nijman J, van Loon K, Koomen E, Allegaert K, Benders MJNL, Dorlo TPC, Huitema ADR; CRUCIAL trial consortium. Chu WY, et al. Clin Pharmacokinet. 2024 Aug;63(8):1205-1220. doi: 10.1007/s40262-024-01401-3. Epub 2024 Aug 15. Clin Pharmacokinet. 2024. PMID: 39147988 Free PMC article. Clinical Trial.
Two dose levels of once-weekly fosravuconazole versus daily itraconazole in combination with surgery in patients with eumycetoma in Sudan: a randomised, double-blind, phase 2, proof-of-concept superiority trial.
Fahal AH, Ahmed ES, Bakhiet SM, Bakhiet OE, Fahal LA, Mohamed AA, Mohamedelamin ESW, Bahar MEN, Attalla HY, Siddig EE, Mhmoud NA, Musa AM, van de Sande WWJ, Scherrer B, Oyieko P, Egondi TW, Onyango KO, Hata K, Chu WY, Dorlo TPC, Brüggemann RJ, Nyaoke BA, Strub-Wourgaft N, Zijlstra EE. Fahal AH, et al. Lancet Infect Dis. 2024 Nov;24(11):1254-1265. doi: 10.1016/S1473-3099(24)00404-3. Epub 2024 Aug 1. Lancet Infect Dis. 2024. PMID: 39098321 Clinical Trial.
Development and validation of an ultra-performance liquid chromatography-tandem mass spectrometry method for the quantification of the antimalarial drug pyronaridine in human whole blood.
Schouten WM, Roseboom IC, Lucas L, Kabalu Tshiongo J, Muhindo Mavoko H, Kayentao K, Rosing H, Huitema ADR, Beijnen JH, Dorlo TPC. Schouten WM, et al. J Pharm Biomed Anal. 2024 Aug 1;245:116154. doi: 10.1016/j.jpba.2024.116154. Epub 2024 Apr 16. J Pharm Biomed Anal. 2024. PMID: 38657367 Free article.
Safety and efficacy of paromomycin/miltefosine/liposomal amphotericin B combinations for the treatment of post-kala-azar dermal leishmaniasis in Sudan: A phase II, open label, randomized, parallel arm study.
Younis BM, Mudawi Musa A, Monnerat S, Abdelrahim Saeed M, Awad Gasim Khalil E, Elbashir Ahmed A, Ahmed Ali M, Noureldin A, Muthoni Ouattara G, Nyakaya GM, Teshome S, Omollo T, Ochieng M, Egondi T, Mmbone M, Chu WY, Dorlo TPC, Zijlstra EE, Wasunna M, Alvar J, Alves F. Younis BM, et al. PLoS Negl Trop Dis. 2023 Nov 21;17(11):e0011780. doi: 10.1371/journal.pntd.0011780. eCollection 2023 Nov. PLoS Negl Trop Dis. 2023. PMID: 37988402 Free PMC article. Clinical Trial.
Efficacy and safety of pyronaridine-artesunate (PYRAMAX) for the treatment of P. falciparum uncomplicated malaria in African pregnant women (PYRAPREG): study protocol for a phase 3, non-inferiority, randomised open-label clinical trial.
Djimde M, Tshiongo JK, Muhindo HM, Tinto H, Sevene E, Traore M, Vala A, Macuacua S, Kabore B, Dabira ED, Erhart A, Diakite H, Keita M, Piqueras M, González R, Menendez C, Dorlo TP, Sagara I, Mens P, Schallig H, D'Alessandro U, Kayentao K. Djimde M, et al. BMJ Open. 2023 Oct 9;13(10):e065295. doi: 10.1136/bmjopen-2022-065295. BMJ Open. 2023. PMID: 37813539 Free PMC article.
High accumulation of nivolumab in human breast milk: A case report.
de Jong K, Damoiseaux D, Pluim D, Rosing H, Beijnen JH, van Thienen H, Dorlo TPC, Huitema ADR, Amant F. de Jong K, et al. Biomed Pharmacother. 2023 Oct;166:115354. doi: 10.1016/j.biopha.2023.115354. Epub 2023 Aug 23. Biomed Pharmacother. 2023. PMID: 37625324 Free article.
Development and validation of an ultra-high performance liquid chromatography coupled to tandem mass spectrometry method for the quantification of the antileishmanial drug paromomycin in human skin tissue.
Roseboom IC, Thijssen B, Rosing H, Alves F, Younis BM, Musa AM, Beijnen JH, Dorlo TPC. Roseboom IC, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2022 Nov 15;1211:123494. doi: 10.1016/j.jchromb.2022.123494. Epub 2022 Oct 7. J Chromatogr B Analyt Technol Biomed Life Sci. 2022. PMID: 36219923 Free article.
Paromomycin and Miltefosine Combination as an Alternative to Treat Patients With Visceral Leishmaniasis in Eastern Africa: A Randomized, Controlled, Multicountry Trial.
Musa AM, Mbui J, Mohammed R, Olobo J, Ritmeijer K, Alcoba G, Muthoni Ouattara G, Egondi T, Nakanwagi P, Omollo T, Wasunna M, Verrest L, Dorlo TPC, Musa Younis B, Nour A, Taha Ahmed Elmukashfi E, Ismail Omer Haroun A, Khalil EAG, Njenga S, Fikre H, Mekonnen T, Mersha D, Sisay K, Sagaki P, Alvar J, Solomos A, Alves F. Musa AM, et al. Clin Infect Dis. 2023 Feb 8;76(3):e1177-e1185. doi: 10.1093/cid/ciac643. Clin Infect Dis. 2023. PMID: 36164254 Free PMC article. Clinical Trial.
Development and validation of a high-performance liquid chromatography tandem mass spectrometry method for the quantification of the antiparasitic and antifungal drug amphotericin B in human skin tissue.
Roseboom IC, Thijssen B, Rosing H, Alves F, Sundar S, Beijnen JH, Dorlo TPC. Roseboom IC, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2022 Aug 15;1206:123354. doi: 10.1016/j.jchromb.2022.123354. Epub 2022 Jul 4. J Chromatogr B Analyt Technol Biomed Life Sci. 2022. PMID: 35810536 Free article.
Development of a population pharmacokinetic/pharmacodynamic model for various oral paclitaxel formulations co-administered with ritonavir and thrombospondin-1 based on data from early phase clinical studies.
van Eijk M, Yu H, Sawicki E, de Weger VA, Nuijen B, Dorlo TPC, Beijnen JH, Huitema ADR. van Eijk M, et al. Cancer Chemother Pharmacol. 2022 Jul;90(1):71-82. doi: 10.1007/s00280-022-04445-z. Epub 2022 Jul 7. Cancer Chemother Pharmacol. 2022. PMID: 35799067 Free PMC article.
No evidence for cardiotoxicity of miltefosine.
Dorlo TPC. Dorlo TPC. An Bras Dermatol. 2022 Jul-Aug;97(4):548-549. doi: 10.1016/j.abd.2022.03.002. Epub 2022 May 30. An Bras Dermatol. 2022. PMID: 35654652 Free PMC article. No abstract available.
Pharmacokinetic/Pharmacodynamic Modelling of Allopurinol, its Active Metabolite Oxypurinol, and Biomarkers Hypoxanthine, Xanthine and Uric Acid in Hypoxic-Ischemic Encephalopathy Neonates.
Chu WY, Annink KV, Nijstad AL, Maiwald CA, Schroth M, Bakkali LE, van Bel F, Benders MJNL, van Weissenbruch MM, Hagen A, Franz AR, Dorlo TPC, Allegaert K, Huitema ADR; ALBINO Study Group. Chu WY, et al. Clin Pharmacokinet. 2022 Feb;61(2):321-333. doi: 10.1007/s40262-021-01068-0. Epub 2021 Oct 7. Clin Pharmacokinet. 2022. PMID: 34617261 Free PMC article. Clinical Trial.
Geographical Variability in Paromomycin Pharmacokinetics Does Not Explain Efficacy Differences between Eastern African and Indian Visceral Leishmaniasis Patients.
Verrest L, Wasunna M, Kokwaro G, Aman R, Musa AM, Khalil EAG, Mudawi M, Younis BM, Hailu A, Hurissa Z, Hailu W, Tesfaye S, Makonnen E, Mekonnen Y, Huitema ADR, Beijnen JH, Kshirsagar SA, Chakravarty J, Rai M, Sundar S, Alves F, Dorlo TPC. Verrest L, et al. Clin Pharmacokinet. 2021 Nov;60(11):1463-1473. doi: 10.1007/s40262-021-01036-8. Epub 2021 Jun 9. Clin Pharmacokinet. 2021. PMID: 34105063 Free PMC article.
Population Pharmacokinetics of Docetaxel, Paclitaxel, Doxorubicin and Epirubicin in Pregnant Women with Cancer: A Study from the International Network of Cancer, Infertility and Pregnancy (INCIP).
Janssen JM, Van Calsteren K, Dorlo TPC, Halaska MJ, Fruscio R, Ottevanger P, Schröder CP, Boere I, Witteveen PO, Painter RC, Bekkers R, Drochytek V, Beijnen JH, Huitema ADR, Amant FCH. Janssen JM, et al. Clin Pharmacokinet. 2021 Jun;60(6):775-784. doi: 10.1007/s40262-020-00961-4. Epub 2021 Jan 28. Clin Pharmacokinet. 2021. PMID: 33506375
Population pharmacokinetic analysis of nanoparticle-bound and free camptothecin after administration of NLG207 in adults with advanced solid tumors.
Schmidt KT, Huitema ADR, Dorlo TPC, Peer CJ, Cordes LM, Sciuto L, Wroblewski S, Pommier Y, Madan RA, Thomas A, Figg WD. Schmidt KT, et al. Cancer Chemother Pharmacol. 2020 Oct;86(4):475-486. doi: 10.1007/s00280-020-04134-9. Epub 2020 Sep 8. Cancer Chemother Pharmacol. 2020. PMID: 32897402 Free PMC article. Clinical Trial.
A Semi-Mechanistic Population Pharmacokinetic/Pharmacodynamic Model of Bortezomib in Pediatric Patients with Relapsed/Refractory Acute Lymphoblastic Leukemia.
Janssen JM, Dorlo TPC, Niewerth D, Wilhelm AJ, Zwaan CM, Beijnen JH, Attarbaschi A, Baruchel A, Fagioli F, Klingebiel T, De Moerloose B, Palumbo G, von Stackelberg A, Kaspers GJL, Huitema ADR. Janssen JM, et al. Clin Pharmacokinet. 2020 Feb;59(2):207-216. doi: 10.1007/s40262-019-00803-y. Clin Pharmacokinet. 2020. PMID: 31313068 Clinical Trial.
Pharmacokinetics, Safety, and Efficacy of an Allometric Miltefosine Regimen for the Treatment of Visceral Leishmaniasis in Eastern African Children: An Open-label, Phase II Clinical Trial.
Mbui J, Olobo J, Omollo R, Solomos A, Kip AE, Kirigi G, Sagaki P, Kimutai R, Were L, Omollo T, Egondi TW, Wasunna M, Alvar J, Dorlo TPC, Alves F. Mbui J, et al. Clin Infect Dis. 2019 Apr 24;68(9):1530-1538. doi: 10.1093/cid/ciy747. Clin Infect Dis. 2019. PMID: 30188978 Free PMC article. Clinical Trial.
Visceral leishmaniasis relapse hazard is linked to reduced miltefosine exposure in patients from Eastern Africa: a population pharmacokinetic/pharmacodynamic study.
Dorlo TPC, Kip AE, Younis BM, Ellis SJ, Alves F, Beijnen JH, Njenga S, Kirigi G, Hailu A, Olobo J, Musa AM, Balasegaram M, Wasunna M, Karlsson MO, Khalil EAG. Dorlo TPC, et al. J Antimicrob Chemother. 2017 Nov 1;72(11):3131-3140. doi: 10.1093/jac/dkx283. J Antimicrob Chemother. 2017. PMID: 28961737 Free PMC article. Clinical Trial.
Efficacy and Safety of AmBisome in Combination with Sodium Stibogluconate or Miltefosine and Miltefosine Monotherapy for African Visceral Leishmaniasis: Phase II Randomized Trial.
Wasunna M, Njenga S, Balasegaram M, Alexander N, Omollo R, Edwards T, Dorlo TP, Musa B, Ali MH, Elamin MY, Kirigi G, Juma R, Kip AE, Schoone GJ, Hailu A, Olobo J, Ellis S, Kimutai R, Wells S, Khalil EA, Strub Wourgaft N, Alves F, Musa A. Wasunna M, et al. PLoS Negl Trop Dis. 2016 Sep 14;10(9):e0004880. doi: 10.1371/journal.pntd.0004880. eCollection 2016 Sep. PLoS Negl Trop Dis. 2016. PMID: 27627654 Free PMC article. Clinical Trial.
Assessment of blood-brain barrier penetration of miltefosine used to treat a fatal case of granulomatous amebic encephalitis possibly caused by an unusual Balamuthia mandrillaris strain.
Roy SL, Atkins JT, Gennuso R, Kofos D, Sriram RR, Dorlo TP, Hayes T, Qvarnstrom Y, Kucerova Z, Guglielmo BJ, Visvesvara GS. Roy SL, et al. Parasitol Res. 2015 Dec;114(12):4431-9. doi: 10.1007/s00436-015-4684-8. Epub 2015 Sep 2. Parasitol Res. 2015. PMID: 26329128 Free PMC article.
Safety and efficacy of single dose versus multiple doses of AmBisome for treatment of visceral leishmaniasis in eastern Africa: a randomised trial.
Khalil EA, Weldegebreal T, Younis BM, Omollo R, Musa AM, Hailu W, Abuzaid AA, Dorlo TP, Hurissa Z, Yifru S, Haleke W, Smith PG, Ellis S, Balasegaram M, EL-Hassan AM, Schoone GJ, Wasunna M, Kimutai R, Edwards T, Hailu A. Khalil EA, et al. PLoS Negl Trop Dis. 2014 Jan 16;8(1):e2613. doi: 10.1371/journal.pntd.0002613. eCollection 2014. PLoS Negl Trop Dis. 2014. PMID: 24454970 Free PMC article. Clinical Trial.
Reply to Arya and Agarwal.
Dorlo TP, Ostyn BA, Beijnen JH, Boelaert M, Dujardin JC, Rijal S. Dorlo TP, et al. Clin Infect Dis. 2013 Sep;57(6):917-8. doi: 10.1093/cid/cit388. Epub 2013 Jun 11. Clin Infect Dis. 2013. PMID: 23759350 No abstract available.
The global impact of Indian generics on access to health.
Ravinetto RM, Dorlo TP, Caudron JM, Prashanth NS. Ravinetto RM, et al. Indian J Med Ethics. 2013 Apr-Jun;10(2):118-20. doi: 10.20529/IJME.2013.035. Indian J Med Ethics. 2013. PMID: 23697493 Free article. No abstract available.
Lopinavir/ritonavir significantly influences pharmacokinetic exposure of artemether/lumefantrine in HIV-infected Ugandan adults.
Byakika-Kibwika P, Lamorde M, Okaba-Kayom V, Mayanja-Kizza H, Katabira E, Hanpithakpong W, Pakker N, Dorlo TP, Tarning J, Lindegardh N, de Vries PJ, Back D, Khoo S, Merry C. Byakika-Kibwika P, et al. J Antimicrob Chemother. 2012 May;67(5):1217-23. doi: 10.1093/jac/dkr596. Epub 2012 Feb 8. J Antimicrob Chemother. 2012. PMID: 22316571 Free PMC article. Clinical Trial.
Safety and efficacy of miltefosine alone and in combination with sodium stibogluconate and liposomal amphotericin B for the treatment of primary visceral leishmaniasis in East Africa: study protocol for a randomized controlled trial.
Omollo R, Alexander N, Edwards T, Khalil EA, Younis BM, Abuzaid AA, Wasunna M, Njoroge N, Kinoti D, Kirigi G, Dorlo TP, Ellis S, Balasegaram M, Musa AM. Omollo R, et al. Trials. 2011 Jun 30;12:166. doi: 10.1186/1745-6215-12-166. Trials. 2011. PMID: 21718522 Free PMC article. Clinical Trial.
Pentamidine dosage: a base/salt confusion.
Dorlo TP, Kager PA. Dorlo TP, et al. PLoS Negl Trop Dis. 2008 May 28;2(5):e225. doi: 10.1371/journal.pntd.0000225. PLoS Negl Trop Dis. 2008. PMID: 18509543 Free PMC article.
[Miltefosine: a new remedy for leishmaniasis].
Dorlo TP, Eggelte TA, Beijnen JH, de Vries PJ. Dorlo TP, et al. Ned Tijdschr Geneeskd. 2006 Dec 9;150(49):2697-701. Ned Tijdschr Geneeskd. 2006. PMID: 17194005 Review. Dutch.