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[The mechanisms of anti-inflammatory action of enisamium iodide].
Kareva EN, Fedotcheva TA, Semeikin AV, Kochina NA, Krasnoshchok EV, Shimanovskii NL. Kareva EN, et al. Ter Arkh. 2022 Dec 26;94(11):1262-1267. doi: 10.26442/00403660.2022.11.201961. Ter Arkh. 2022. PMID: 37167164 Russian.
At 5 times higher concentration, 50 muM, enisamium iodide suppressed the expression of these genes by an average of 43% (p0.05). ...At a concentration of 10 muM, enisamium iodide stimulated the secretion of IL-10 by mononuclear cells by 1.2 times, p0.0 …
At 5 times higher concentration, 50 muM, enisamium iodide suppressed the expression of these genes by an average of 43% (p0.05 …
In Vitro Bioavailability Study of an Antiviral Compound Enisamium Iodide.
Haltner-Ukomadu E, Gureyeva S, Burmaka O, Goy A, Mueller L, Kostyuk G, Margitich V. Haltner-Ukomadu E, et al. Sci Pharm. 2018 Jan 11;86(1):3. doi: 10.3390/scipharm86010003. Sci Pharm. 2018. PMID: 29324660 Free PMC article.
The solubility of enisamium iodide was determined in four different buffers. Apparent intestinal permeability (P(app)) of enisamium iodide was assessed using human colon carcinoma (Caco-2) cells at three concentrations. ...The bioavailability of eni …
The solubility of enisamium iodide was determined in four different buffers. Apparent intestinal permeability (P(app)) of e …
[Anti-viral activity of enisamium iodide against viruses of influenza and ARVI's on different cell lines].
Zarubaev VV, Slita AV, Sinegubova EO, Muryleva AA, Lavrentieva IN. Zarubaev VV, et al. Ter Arkh. 2020 Dec 26;92(11):45-50. doi: 10.26442/00403660.2020.11.000872. Ter Arkh. 2020. PMID: 33720603 Russian.
MATERIALS AND METHODS: In the course of experiments, the cytotoxic properties of enisamium iodide were studied against the cell lines Vero, MA-104, A549, L-41 and HEp-2. ...The antiviral activity of enisamium iodide was least manifested in Vero cells. …
MATERIALS AND METHODS: In the course of experiments, the cytotoxic properties of enisamium iodide were studied against the cel …
Enisamium Reduces Influenza Virus Shedding and Improves Patient Recovery by Inhibiting Viral RNA Polymerase Activity.
Te Velthuis AJW, Zubkova TG, Shaw M, Mehle A, Boltz D, Gmeinwieser N, Stammer H, Milde J, Müller L, Margitich V. Te Velthuis AJW, et al. Antimicrob Agents Chemother. 2021 Mar 18;65(4):e02605-20. doi: 10.1128/AAC.02605-20. Print 2021 Mar 18. Antimicrob Agents Chemother. 2021. PMID: 33558285 Free PMC article.
Antivirals against some respiratory viruses are available, but further options are urgently needed. Enisamium iodide (laboratory code FAV00A, trade name Amizon) is an antiviral, marketed in countries of the Commonwealth of Independent States for the treatment of vir …
Antivirals against some respiratory viruses are available, but further options are urgently needed. Enisamium iodide (laborato …
Antiviral effect of a derivative of isonicotinic acid enisamium iodide (FAV00A) against influenza virus.
Cocking D, Cinatl J, Boltz DA, Peng X, Johnson W, Muzzio M, Syarkevych O, Kostyuk G, Goy A, Mueller L, Margitich VI. Cocking D, et al. Acta Virol. 2018;62(2):191-195. doi: 10.4149/av_2018_211. Acta Virol. 2018. PMID: 29895160
With only a single class of antiviral drugs existing for treatment of influenza (neuraminidase inhibitors), the search for novel effective compounds is urgently needed. We evaluated a low molecular mass compound, enisamium iodide (FAV00A), against influenza virus in …
With only a single class of antiviral drugs existing for treatment of influenza (neuraminidase inhibitors), the search for novel effective c …
Activity of enisamium, an isonicotinic acid derivative, against influenza viruses in differentiated normal human bronchial epithelial cells.
Boltz D, Peng X, Muzzio M, Dash P, Thomas PG, Margitich V. Boltz D, et al. Antivir Chem Chemother. 2018 Jan-Dec;26:2040206618811416. doi: 10.1177/2040206618811416. Antivir Chem Chemother. 2018. PMID: 30466301 Free PMC article.
AIMS: New therapeutics for the control of influenza virus infections are needed to alleviate the burden caused by seasonal epidemics and occasional pandemics, and to overcome the potential risk of drug-resistance emergence. Enisamium iodide (Amizon, Farmak) is curre …
AIMS: New therapeutics for the control of influenza virus infections are needed to alleviate the burden caused by seasonal epidemics and occ …
[Evaluation of the effectiveness of ARVI treatment regimen including etiotropic (enisamium iodide) and symptomatic treatment].
Lioznov DA, Karnaukhova EJ, Zubkova TG, Shakhlanskaya EV. Lioznov DA, et al. Ter Arkh. 2020 Apr 27;92(3):50-55. doi: 10.26442/00403660.2020.03.000572. Ter Arkh. 2020. PMID: 32598793 Russian.
AIM: To assess the effectiveness of the use of the antiviral drug enisamium iodide in the complex treatment of acute respiratory viral infections (ARVI) caused by various pathogens in routine clinical practice. ...Prescription of additional therapy was required in 2 …
AIM: To assess the effectiveness of the use of the antiviral drug enisamium iodide in the complex treatment of acute respirato …
Histomorphological Study of a New Nasal Spray with Anti-inflammatory Properties Efficacy in Rabbits with Rhinosinusitis.
Zupanets I, Zhulai T, Shebeko S, Otrishko I, Hladkykh D. Zupanets I, et al. Med Arch. 2020 Feb;74(1):8-13. doi: 10.5455/medarh.2020.74.8-13. Med Arch. 2020. PMID: 32317827 Free PMC article.
AIM: To substantiate the efficacy of a new nasal spray with anti-inflammatory properties containing Enisamium Iodide (EI) at a concentration of 10 mg/mL by histomorphological study of the nasal cavity and paranasal sinuses mucosal in rabbits with experimental rhinos …
AIM: To substantiate the efficacy of a new nasal spray with anti-inflammatory properties containing Enisamium Iodide (EI) at a …
[Review of current and future directions of antiviral therapy of influenza and acute respiratory viral infections in Russia].
Pshenichnaya NY, Bulgakova VA, Volchkova EV, Kareva EN, Selkova EP, Gorodin VN. Pshenichnaya NY, et al. Ter Arkh. 2019 Nov 15;91(11):105-109. doi: 10.26442/00403660.2019.11.000454. Ter Arkh. 2019. PMID: 32598620 Russian.
Positive clinical and laboratory data in clinical trials were obtained using Enisamium iodide, a drug with combined action - direct antiviral, and immunomodulatory. ...
Positive clinical and laboratory data in clinical trials were obtained using Enisamium iodide, a drug with combined action - d …
11 results