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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1908 1
1921 1
1929 1
1939 1
1942 1
1945 1
1946 4
1947 1
1948 2
1949 6
1950 1
1954 1
1956 2
1957 3
1959 3
1960 5
1961 10
1962 6
1963 3
1964 3
1965 2
1966 2
1967 1
1968 9
1969 6
1970 11
1971 4
1972 9
1973 11
1974 16
1975 24
1976 17
1977 12
1978 22
1979 29
1980 16
1981 29
1982 26
1983 41
1984 46
1985 35
1986 31
1987 46
1988 38
1989 41
1990 38
1991 63
1992 39
1993 41
1994 65
1995 67
1996 77
1997 59
1998 68
1999 78
2000 80
2001 91
2002 90
2003 112
2004 116
2005 157
2006 183
2007 205
2008 189
2009 201
2010 236
2011 288
2012 311
2013 324
2014 331
2015 345
2016 359
2017 415
2018 442
2019 457
2020 503
2021 551
2022 535
2023 537
2024 232

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7,339 results

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Page 1
Manganese Toxicity Upon Overexposure: a Decade in Review.
O'Neal SL, Zheng W. O'Neal SL, et al. Curr Environ Health Rep. 2015 Sep;2(3):315-28. doi: 10.1007/s40572-015-0056-x. Curr Environ Health Rep. 2015. PMID: 26231508 Free PMC article. Review.
Exposure to manganese (Mn) causes clinical signs and symptoms resembling, but not identical to, Parkinson's disease. ...Recent data suggest Mn accumulates substantially in bone, with a half-life of about 8-9 years expected in human bones. Mn toxicity has been associ …
Exposure to manganese (Mn) causes clinical signs and symptoms resembling, but not identical to, Parkinson's disease. ...Recent data s …
Genetics and Epigenetics of Manganese Toxicity.
Lindner S, Lucchini R, Broberg K. Lindner S, et al. Curr Environ Health Rep. 2022 Dec;9(4):697-713. doi: 10.1007/s40572-022-00384-2. Epub 2022 Nov 10. Curr Environ Health Rep. 2022. PMID: 36357556 Free PMC article. Review.
PURPOSE OF REVIEW: At elevated levels, the essential element manganese (Mn) is neurotoxic and increasing evidence indicates that environmental Mn exposure early in life negatively affects neurodevelopment. ...Genetic variation in iron regulatory genes may to lesser extent …
PURPOSE OF REVIEW: At elevated levels, the essential element manganese (Mn) is neurotoxic and increasing evidence indicates that envi …
Manganese: Its Role in Disease and Health.
Erikson KM, Aschner M. Erikson KM, et al. Met Ions Life Sci. 2019 Jan 14;19:/books/9783110527872/9783110527872-016/9783110527872-016.xml. doi: 10.1515/9783110527872-016. Met Ions Life Sci. 2019. PMID: 30855111 Free article. Review.
Manganese is an essential dietary element that functions primarily as a coenzyme in several biological processes. ...However, overexposure to environmental Mn via industrial occupation or contaminated drinking water can lead to toxic brain Mn accumulation that has b
Manganese is an essential dietary element that functions primarily as a coenzyme in several biological processes. ...However, overexp
CBL1/9-CIPK23-NRAMP1 axis regulates manganese toxicity.
Zhang Z, Fu D, Xie D, Wang Z, Zhao Y, Ma X, Huang P, Ju C, Wang C. Zhang Z, et al. New Phytol. 2023 Jul;239(2):660-672. doi: 10.1111/nph.18968. Epub 2023 May 23. New Phytol. 2023. PMID: 37219876
Manganese (Mn) is an essential micronutrient in plants. However, excessive Mn absorption in acidic soils can cause Mn toxicity, which adversely affects plant growth and crop yields. ...In addition, CIPK23 interacted with and phosphorylated the Mn transporter NRAMP1
Manganese (Mn) is an essential micronutrient in plants. However, excessive Mn absorption in acidic soils can cause Mn toxicity
Consequences of Disturbing Manganese Homeostasis.
Baj J, Flieger W, Barbachowska A, Kowalska B, Flieger M, Forma A, Teresiński G, Portincasa P, Buszewicz G, Radzikowska-Büchner E, Flieger J. Baj J, et al. Int J Mol Sci. 2023 Oct 6;24(19):14959. doi: 10.3390/ijms241914959. Int J Mol Sci. 2023. PMID: 37834407 Free PMC article. Review.
However, overexposure to Mn is toxic, particularly to the central nervous system (CNS) due to it causing the progressive destruction of nerve cells. Exposure to manganese is widespread and occurs by inhalation, ingestion, or dermal contact. ...
However, overexposure to Mn is toxic, particularly to the central nervous system (CNS) due to it causing the progressive destruction …
Influence of iron metabolism on manganese transport and toxicity.
Ye Q, Park JE, Gugnani K, Betharia S, Pino-Figueroa A, Kim J. Ye Q, et al. Metallomics. 2017 Aug 16;9(8):1028-1046. doi: 10.1039/c7mt00079k. Metallomics. 2017. PMID: 28620665 Free PMC article. Review.
Although manganese (Mn) is critical for the proper functioning of various metabolic enzymes and cofactors, excess Mn in the brain causes neurotoxicity. ...The present review will provide an update on the role of altered iron status in the transport and toxicity of M …
Although manganese (Mn) is critical for the proper functioning of various metabolic enzymes and cofactors, excess Mn in the brain cau …
Manganese toxicity in the central nervous system: the glutamine/glutamate-gamma-aminobutyric acid cycle.
Sidoryk-Wegrzynowicz M, Aschner M. Sidoryk-Wegrzynowicz M, et al. J Intern Med. 2013 May;273(5):466-77. doi: 10.1111/joim.12040. J Intern Med. 2013. PMID: 23360507 Free PMC article. Review.
Manganese (Mn) is an essential trace element that is required for maintaining proper function and regulation of numerous biochemical and cellular reactions. Despite its essentiality, at excessive levels Mn is toxic to the central nervous system (CNS). Increased accu
Manganese (Mn) is an essential trace element that is required for maintaining proper function and regulation of numerous biochemical
Relationships Between Essential Manganese Biology and Manganese Toxicity in Neurological Disease.
Pfalzer AC, Bowman AB. Pfalzer AC, et al. Curr Environ Health Rep. 2017 Jun;4(2):223-228. doi: 10.1007/s40572-017-0136-1. Curr Environ Health Rep. 2017. PMID: 28417441 Free PMC article. Review.
PURPOSE OF REVIEW: Manganese (Mn) is critical for neurodevelopment but also has been implicated in the pathophysiology of several neurological diseases. We discuss how Mn requirements intersect with Mn biology and toxicity, and how these requirements may be altered …
PURPOSE OF REVIEW: Manganese (Mn) is critical for neurodevelopment but also has been implicated in the pathophysiology of several neu …
Association between manganese exposure in heavy metals mixtures and the prevalence of sarcopenia in US adults from NHANES 2011-2018.
Huang Q, Wan J, Nan W, Li S, He B, Peng Z. Huang Q, et al. J Hazard Mater. 2024 Feb 15;464:133005. doi: 10.1016/j.jhazmat.2023.133005. Epub 2023 Nov 15. J Hazard Mater. 2024. PMID: 37988867
Environmental pollution is identified as an essential risk factor for sarcopenia. However, the effect of manganese (Mn) exposure on the prevalence of sarcopenia is not assessed. ...
Environmental pollution is identified as an essential risk factor for sarcopenia. However, the effect of manganese (Mn) exposure on t …
New insights into manganese toxicity and speciation.
Michalke B, Fernsebner K. Michalke B, et al. J Trace Elem Med Biol. 2014 Apr;28(2):106-116. doi: 10.1016/j.jtemb.2013.08.005. Epub 2013 Sep 14. J Trace Elem Med Biol. 2014. PMID: 24200516 Review.
Manganese (Mn) is known to be a neurotoxic agent for nearly 175 years now. ...From preliminary describing only symptoms of Mn-(over)exposed workers, research was preceded to more detail on toxic mechanisms of Mn. Unraveling those neurotoxic mechanisms implicated a n
Manganese (Mn) is known to be a neurotoxic agent for nearly 175 years now. ...From preliminary describing only symptoms of Mn-(over)e
7,339 results