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Showing results for meclozine
Your search for mecolzine retrieved no results
Meclozine ameliorates skeletal muscle pathology and increases muscle forces in mdx mice.
Kawamura Y, Hida T, Ohkawara B, Matsushita M, Kobayashi T, Ishizuka S, Hiraiwa H, Tanaka S, Tsushima M, Nakashima H, Ito K, Imagama S, Ito M, Masuda A, Ishiguro N, Ohno K. Kawamura Y, et al. Biochem Biophys Res Commun. 2022 Feb 12;592:87-92. doi: 10.1016/j.bbrc.2022.01.003. Epub 2022 Jan 7. Biochem Biophys Res Commun. 2022. PMID: 35033871
Withdrawal of meclozine, however, resumed the ability of Hu5/KD3 cells to differentiate into myotubes. ...This was likely to be one of the underlying mechanisms of the effects of meclozine on mdx mice....
Withdrawal of meclozine, however, resumed the ability of Hu5/KD3 cells to differentiate into myotubes. ...This was likely to be one o …
Meclozine Attenuates the MARK Pathway in Mammalian Chondrocytes and Ameliorates FGF2-Induced Bone Hyperossification in Larval Zebrafish.
Takemoto G, Matsushita M, Okamoto T, Ito T, Matsuura Y, Takashima C, Chen-Yoshikawa TF, Ebi H, Imagama S, Kitoh H, Ohno K, Hosono Y. Takemoto G, et al. Front Cell Dev Biol. 2022 Jan 18;9:694018. doi: 10.3389/fcell.2021.694018. eCollection 2021. Front Cell Dev Biol. 2022. PMID: 35118060 Free PMC article.
Meclozine has been developed as an inhibitor of fibroblast growth factor receptor 3 (FGFR3) to treat achondroplasia (ACH). ...Next, we administered meclozine to FGF2-treated larval zebrafish from 8 h post-fertilization (hpf). ...
Meclozine has been developed as an inhibitor of fibroblast growth factor receptor 3 (FGFR3) to treat achondroplasia (ACH). ...Next, w …
Meclozine ameliorates bone mineralization and growth plate structure in a mouse model of X-linked hypophosphatemia.
Kamiya Y, Matsushita M, Mishima K, Ohkawara B, Michigami T, Imagama S, Ohno K, Kitoh H. Kamiya Y, et al. Exp Ther Med. 2022 Nov 30;25(1):39. doi: 10.3892/etm.2022.11738. eCollection 2023 Jan. Exp Ther Med. 2022. PMID: 36569439 Free PMC article.
However, meclozine had only a marginal effect on mineralization in the trabecular bone and on calcium and phosphate plasma levels. A 10-day-tratment with meclozine partially ameliorated bone mineralization in Hyp mice; hence, meclozine could alleviate XLH sym …
However, meclozine had only a marginal effect on mineralization in the trabecular bone and on calcium and phosphate plasma levels. A …
Drugs for preventing postoperative nausea and vomiting in adults after general anaesthesia: a network meta-analysis.
Weibel S, Rücker G, Eberhart LH, Pace NL, Hartl HM, Jordan OL, Mayer D, Riemer M, Schaefer MS, Raj D, Backhaus I, Helf A, Schlesinger T, Kienbaum P, Kranke P. Weibel S, et al. Cochrane Database Syst Rev. 2020 Oct 19;10(10):CD012859. doi: 10.1002/14651858.CD012859.pub2. Cochrane Database Syst Rev. 2020. PMID: 33075160 Free PMC article.
We performed pair-wise meta-analyses for drugs of direct interest (amisulpride, aprepitant, casopitant, dexamethasone, dimenhydrinate, dolasetron, droperidol, fosaprepitant, granisetron, haloperidol, meclizine, methylprednisolone, metoclopramide, ondansetron, palonosetron, …
We performed pair-wise meta-analyses for drugs of direct interest (amisulpride, aprepitant, casopitant, dexamethasone, dimenhydrinate, dolas …
Meclozine promotes longitudinal skeletal growth in transgenic mice with achondroplasia carrying a gain-of-function mutation in the FGFR3 gene.
Matsushita M, Hasegawa S, Kitoh H, Mori K, Ohkawara B, Yasoda A, Masuda A, Ishiguro N, Ohno K. Matsushita M, et al. Endocrinology. 2015 Feb;156(2):548-54. doi: 10.1210/en.2014-1914. Epub 2014 Dec 2. Endocrinology. 2015. PMID: 25456072
To examine the feasibility of meclozine administration in clinical settings, we investigated the effects of meclozine on ACH model mice carrying the heterozygous Fgfr3(ach) transgene. ...Increased longitudinal bone growth in Fgfr3(ach) mice by oral administration of …
To examine the feasibility of meclozine administration in clinical settings, we investigated the effects of meclozine on ACH m …
Meclizine.
Houston BT, Patel P, Chowdhury YS. Houston BT, et al. 2024 Feb 28. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. 2024 Feb 28. In: StatPearls [Internet]. Treasure Island (FL): StatPearls Publishing; 2024 Jan–. PMID: 32809480 Free Books & Documents.
Meclizine is an FDA-approved first-generation antihistamine used to alleviate motion sickness. By acting as a non-selective H1 antagonist, meclizine addresses the symptoms associated with motion sickness, including dizziness, nausea, and vomiting. ...
Meclizine is an FDA-approved first-generation antihistamine used to alleviate motion sickness. By acting as a non-selective H1 antago …
Meclizine.
[No authors listed] [No authors listed] 2021 Sep 20. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. 2021 Sep 20. Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006–. PMID: 30000495 Free Books & Documents. Review.
Occasional doses of meclizine are probably acceptable during breastfeeding. Large doses or more prolonged use may cause effects in the infant or decrease the milk supply, particularly in combination with a sympathomimetic such as pseudoephedrine or before lactation is well …
Occasional doses of meclizine are probably acceptable during breastfeeding. Large doses or more prolonged use may cause effects in th …
Meclizine.
[No authors listed] [No authors listed] 2023 Jul. Mother To Baby | Fact Sheets [Internet]. Brentwood (TN): Organization of Teratology Information Specialists (OTIS); 1994–. 2023 Jul. Mother To Baby | Fact Sheets [Internet]. Brentwood (TN): Organization of Teratology Information Specialists (OTIS); 1994–. PMID: 35952091 Free Books & Documents. Review.
This sheet is about exposure to meclizine in pregnancy and while breastfeeding. This information is based on available published literature. ...
This sheet is about exposure to meclizine in pregnancy and while breastfeeding. This information is based on available published lite …
Meclozine facilitates proliferation and differentiation of chondrocytes by attenuating abnormally activated FGFR3 signaling in achondroplasia.
Matsushita M, Kitoh H, Ohkawara B, Mishima K, Kaneko H, Ito M, Masuda A, Ishiguro N, Ohno K. Matsushita M, et al. PLoS One. 2013 Dec 4;8(12):e81569. doi: 10.1371/journal.pone.0081569. eCollection 2013. PLoS One. 2013. PMID: 24324705 Free PMC article.
Interestingly, meclozine enhanced growth of embryonic tibia in explant culture even in the absence of FGF2 treatment. ...Similarly, meclozine enhanced proliferation of RCS cells expressing constitutively active mutants of MEK and RAF but not of ERK, which suggests t …
Interestingly, meclozine enhanced growth of embryonic tibia in explant culture even in the absence of FGF2 treatment. ...Similarly, …
Meclizine.
[No authors listed] [No authors listed] 2017 Jan 16. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2017 Jan 16. LiverTox: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31643231 Free Books & Documents. Review.
Meclizine is a first generation antihistamine that is used largely to treat vertigo and motion sickness. Meclizine has not been linked to instances of clinically apparent acute liver injury....
Meclizine is a first generation antihistamine that is used largely to treat vertigo and motion sickness. Meclizine has not bee …
403 results