Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1964 1
1967 1
1968 1
1969 1
1970 1
1971 1
1973 2
1974 2
1975 2
1976 3
1977 4
1978 10
1979 9
1980 2
1981 2
1982 11
1983 4
1984 8
1985 14
1986 23
1987 11
1988 14
1989 13
1990 21
1991 35
1992 39
1993 53
1994 31
1995 65
1996 93
1997 110
1998 131
1999 131
2000 104
2001 139
2002 115
2003 123
2004 103
2005 169
2006 175
2007 158
2008 149
2009 189
2010 196
2011 205
2012 255
2013 247
2014 282
2015 281
2016 277
2017 278
2018 303
2019 367
2020 423
2021 428
2022 450
2023 462
2024 224

Text availability

Article attribute

Article type

Publication date

Search Results

6,247 results

Results by year

Filters applied: . Clear all
Page 1
Melatonin in sleep disorders.
Poza JJ, Pujol M, Ortega-Albás JJ, Romero O; Insomnia Study Group of the Spanish Sleep Society (SES). Poza JJ, et al. Neurologia (Engl Ed). 2022 Sep;37(7):575-585. doi: 10.1016/j.nrleng.2018.08.004. Epub 2020 Sep 18. Neurologia (Engl Ed). 2022. PMID: 36064286 Free article. Review.
Melatonin is the main hormone involved in the control of the sleep-wake cycle. ...Moreover, as production of the hormone decreases with age, in inverse correlation with the frequency of poor sleep quality, it has been suggested that melatonin deficit i …
Melatonin is the main hormone involved in the control of the sleep-wake cycle. ...Moreover, as production of the hormone decre …
New perspectives on the role of melatonin in human sleep, circadian rhythms and their regulation.
Zisapel N. Zisapel N. Br J Pharmacol. 2018 Aug;175(16):3190-3199. doi: 10.1111/bph.14116. Epub 2018 Jan 15. Br J Pharmacol. 2018. PMID: 29318587 Free PMC article. Review.
Clinically meaningful effects of melatonin treatment have been demonstrated in placebo-controlled trials in humans, particularly in disorders associated with diminished or misaligned melatonin rhythms, for example, circadian rhythm-related sleep disorders, je …
Clinically meaningful effects of melatonin treatment have been demonstrated in placebo-controlled trials in humans, particularly in d …
Melatonin as a Chronobiotic with Sleep-promoting Properties.
Cruz-Sanabria F, Carmassi C, Bruno S, Bazzani A, Carli M, Scarselli M, Faraguna U. Cruz-Sanabria F, et al. Curr Neuropharmacol. 2023;21(4):951-987. doi: 10.2174/1570159X20666220217152617. Curr Neuropharmacol. 2023. PMID: 35176989 Free PMC article. Review.
The use of exogenous melatonin (exo-MEL) as a sleep-promoting drug has been under extensive debate due to the lack of consistency of its described effects. In this study, we conduct a systematic and comprehensive review of the literature on the chronobiotic, slee …
The use of exogenous melatonin (exo-MEL) as a sleep-promoting drug has been under extensive debate due to the lack of consiste …
Role of melatonin in the regulation of human circadian rhythms and sleep.
Cajochen C, Kräuchi K, Wirz-Justice A. Cajochen C, et al. J Neuroendocrinol. 2003 Apr;15(4):432-7. doi: 10.1046/j.1365-2826.2003.00989.x. J Neuroendocrinol. 2003. PMID: 12622846 Review.
The endogenous melatonin rhythm exhibits a close association with the endogenous circadian component of the sleep propensity rhythm. ...We describe the role of melatonin in the regulation of sleep, and the use of exogenous melatonin to treat …
The endogenous melatonin rhythm exhibits a close association with the endogenous circadian component of the sleep propensity r …
Role of Melatonin in the Management of Sleep and Circadian Disorders in the Context of Psychiatric Illness.
Moon E, Kim K, Partonen T, Linnaranta O. Moon E, et al. Curr Psychiatry Rep. 2022 Nov;24(11):623-634. doi: 10.1007/s11920-022-01369-6. Epub 2022 Oct 13. Curr Psychiatry Rep. 2022. PMID: 36227449 Free PMC article. Review.
PURPOSE OF REVIEW: We present a review of research on the role of melatonin in the management of sleep and circadian disorders, stressing current overall view of the knowledge across psychiatric disorders. ...Overall, recent studies in psychiatric disorders reported …
PURPOSE OF REVIEW: We present a review of research on the role of melatonin in the management of sleep and circadian disorders …
Association between light at night, melatonin secretion, sleep deprivation, and the internal clock: Health impacts and mechanisms of circadian disruption.
Touitou Y, Reinberg A, Touitou D. Touitou Y, et al. Life Sci. 2017 Mar 15;173:94-106. doi: 10.1016/j.lfs.2017.02.008. Epub 2017 Feb 16. Life Sci. 2017. PMID: 28214594 Review.
The potential and multifactorial mechanisms of the effects include the suppression of melatonin secretion by ALAN, sleep deprivation, and circadian disruption. ...The IARC has classified shift work in group 2A of "probable carcinogens to humans" since "they involve …
The potential and multifactorial mechanisms of the effects include the suppression of melatonin secretion by ALAN, sleep depri …
Sleep, melatonin, and cardiovascular disease.
Covassin N, Somers VK. Covassin N, et al. Lancet Neurol. 2023 Nov;22(11):979-981. doi: 10.1016/S1474-4422(23)00363-0. Lancet Neurol. 2023. PMID: 37863599 No abstract available.
The Effects of Melatonin Supplementation on Sleep Quality and Assessment of the Serum Melatonin in ICU Patients: A Randomized Controlled Trial.
Gandolfi JV, Di Bernardo APA, Chanes DAV, Martin DF, Joles VB, Amendola CP, Sanches LC, Ciorlia GL, Lobo SM. Gandolfi JV, et al. Crit Care Med. 2020 Dec;48(12):e1286-e1293. doi: 10.1097/CCM.0000000000004690. Crit Care Med. 2020. PMID: 33048904 Clinical Trial.
OBJECTIVES: To evaluate whether the use of exogenous melatonin affects sleep, reduces the prevalence of delirium, and decreases the need for analgosedation and to assess whether serum melatonin indices correlate with exogenous administration in critically ill …
OBJECTIVES: To evaluate whether the use of exogenous melatonin affects sleep, reduces the prevalence of delirium, and decrease …
Melatonin: Physiological effects in humans.
Claustrat B, Leston J. Claustrat B, et al. Neurochirurgie. 2015 Apr-Jun;61(2-3):77-84. doi: 10.1016/j.neuchi.2015.03.002. Epub 2015 Apr 20. Neurochirurgie. 2015. PMID: 25908646 Review.
Although functions of this hormone in humans are mainly based on correlations between clinical observations and melatonin secretion, there is some evidence that melatonin stabilises and strengthens coupling of circadian rhythms, especially of core temperature and …
Although functions of this hormone in humans are mainly based on correlations between clinical observations and melatonin secretion, …
Melatonin improves skin barrier damage caused by sleep restriction through gut microbiota.
Li W, Wang Z, Cao J, Dong Y, Chen Y. Li W, et al. J Pineal Res. 2023 Aug;75(1):e12874. doi: 10.1111/jpi.12874. Epub 2023 Apr 24. J Pineal Res. 2023. PMID: 37057339
We established a 28-day sleep restriction (SR) mice model simulating continuous long-term sleep loss. ...Our research showed that lack of sleep impaired skin barrier function. Oral melatonin could improve skin damage by restoring the circadian rhythm o …
We established a 28-day sleep restriction (SR) mice model simulating continuous long-term sleep loss. ...Our research showed t …
6,247 results

Searches related to "melatonin sleep"