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2003 1
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2009 6
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2014 18
2015 15
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2018 25
2019 28
2020 45
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Page 1
Inhibition of oxidized low-density lipoprotein with orticumab inhibits coronary inflammation and reduces residual inflammatory risk in psoriasis: a pilot randomized, double-blind placebo-controlled trial.
Farina CJ, Davidson MH, Shah PK, Stark C, Lu W, Shirodaria C, Wright T, Antoniades CA, Nilsson J, Mehta NN. Farina CJ, et al. Among authors: mehta nn. Cardiovasc Res. 2024 Mar 25:cvae057. doi: 10.1093/cvr/cvae057. Online ahead of print. Cardiovasc Res. 2024. PMID: 38523341 No abstract available.
Monocyte-to-High-Density Lipoprotein Ratio Is Associated with Systemic Inflammation, Insulin Resistance, and Coronary Subclinical Atherosclerosis in Psoriasis: Results from 2 Observational Cohorts.
Berna-Rico E, Abbad-Jaime de Aragon C, Ballester-Martinez A, Perez-Bootello J, Solis J, Fernandez-Friera L, Llamas-Velasco M, Castellanos-Gonzalez M, Barderas MG, Azcarraga-Llobet C, Garcia-Mouronte E, de Nicolas-Ruanes B, Naharro-Rodriguez J, Jaen-Olasolo P, Gelfand JM, Mehta NN, Gonzalez-Cantero A. Berna-Rico E, et al. Among authors: mehta nn. J Invest Dermatol. 2024 Mar 7:S0022-202X(24)00174-X. doi: 10.1016/j.jid.2024.02.015. Online ahead of print. J Invest Dermatol. 2024. PMID: 38460808
A Care Coordination Model to Prevent Cardiovascular Events in Patients with Psoriatic Disease: A Multicenter Pilot Study.
Song WB, Garshick MS, Barbieri JS, Shin DB, Báez S, Papadopoulos M, Neopaney A, Fitzsimmons R, Kalb RE, Mease PJ, Craig ET, Koplin J, Takeshita J, Chiesa Fuxench ZC, Armstrong AW, Mehta NN, Beidas RS, Ogdie AR, Gelfand JM. Song WB, et al. Among authors: mehta nn. J Invest Dermatol. 2024 Jan 4:S0022-202X(23)03196-2. doi: 10.1016/j.jid.2023.12.008. Online ahead of print. J Invest Dermatol. 2024. PMID: 38184142 No abstract available.
Relationship of Soluble Lectin-Like Low-Density Lipoprotein Receptor-1 (sLOX-1) With Inflammation and Coronary Plaque Progression in Psoriasis.
Florida EM, Li H, Hong CG, Ongstad EL, Gaddipati R, Sitaula S, Varma V, Parel PM, O'Hagan R, Chen MY, Teague HL, Playford MP, Karathanasis SK, Collén A, Mehta NN, Remaley AT, Sorokin AV. Florida EM, et al. Among authors: mehta nn. J Am Heart Assoc. 2023 Nov 20;12(22):e031227. doi: 10.1161/JAHA.123.031227. Online ahead of print. J Am Heart Assoc. 2023. PMID: 37982276 Free PMC article.
Longitudinal association of epicardial and thoracic adipose tissues with coronary and cardiac characteristics in psoriasis.
O'Hagan R, Hsu LY, Li H, Hong CG, Parel PM, Berg AR, Manyak GA, Bui V, Patel NH, Florida EM, Teague HL, Playford MP, Zhou W, Dey D, Chen MY, Mehta NN, Sorokin AV. O'Hagan R, et al. Among authors: mehta nn. Heliyon. 2023 Oct 11;9(10):e20732. doi: 10.1016/j.heliyon.2023.e20732. eCollection 2023 Oct. Heliyon. 2023. PMID: 37867905 Free PMC article.
Early Detection and Progression of Subclinical Atherosclerosis in Psoriasis (EDSAP): protocol for an observational, single-centre, prospective cohort study.
Abbad-Jaime de Aragón C, Berna-Rico E, Ballester-Martinez MA, Jaén P, Solís J, Barderas MG, Fernández-Friera L, N Mehta N, Gelfand JM, González-Cantero Á. Abbad-Jaime de Aragón C, et al. Among authors: n mehta n. BMJ Open. 2023 Sep 26;13(9):e072455. doi: 10.1136/bmjopen-2023-072455. BMJ Open. 2023. PMID: 37751953 Free PMC article.
Boosting NAD preferentially blunts Th17 inflammation via arginine biosynthesis and redox control in healthy and psoriasis subjects.
Han K, Singh K, Meadows AM, Sharma R, Hassanzadeh S, Wu J, Goss-Holmes H, Huffstutler RD, Teague HL, Mehta NN, Griffin JL, Tian R, Traba J, Sack MN. Han K, et al. Among authors: mehta nn. Cell Rep Med. 2023 Sep 19;4(9):101157. doi: 10.1016/j.xcrm.2023.101157. Epub 2023 Aug 15. Cell Rep Med. 2023. PMID: 37586364 Free PMC article.
Cell-free, high-density lipoprotein-specific phospholipid efflux assay predicts incident cardiovascular disease.
Sato M, Neufeld EB, Playford MP, Lei Y, Sorokin AV, Aponte AM, Freeman LA, Gordon SM, Dey AK, Jeiran K, Hamasaki M, Sampson ML, Shamburek RD, Tang J, Chen MY, Kotani K, Anderson JL, Dullaart RP, Mehta NN, Tietge UJ, Remaley AT. Sato M, et al. Among authors: mehta nn. J Clin Invest. 2023 Sep 15;133(18):e165370. doi: 10.1172/JCI165370. J Clin Invest. 2023. PMID: 37471145 Free PMC article.
The Relationship between Circulating APOA-1 and Atherosclerosis Initiation and Progression in Psoriasis.
Teague HL, Li H, Berg AR, Hong C, Petrole RF, O'Hagan R, Florida EM, Keel A, Rodante J, Kapoor P, Gonzalez-Cantero A, Sorokin AV, Joshi A, Patel N, Gelfand JM, Playford MP, Mehta NN. Teague HL, et al. Among authors: mehta nn. J Invest Dermatol. 2023 Oct;143(10):1947-1954.e4. doi: 10.1016/j.jid.2023.01.044. Epub 2023 Apr 22. J Invest Dermatol. 2023. PMID: 37088280
Comparison of the dietary omega-3 fatty acids impact on murine psoriasis-like skin inflammation and associated lipid dysfunction.
Sorokin AV, Arnardottir H, Svirydava M, Ng Q, Baumer Y, Berg A, Pantoja CJ, Florida EM, Teague HL, Yang ZH, Dagur PK, Powell-Wiley TM, Yu ZX, Playford MP, Remaley AT, Mehta NN. Sorokin AV, et al. Among authors: mehta nn. J Nutr Biochem. 2023 Jul;117:109348. doi: 10.1016/j.jnutbio.2023.109348. Epub 2023 Apr 11. J Nutr Biochem. 2023. PMID: 37044136 Free article.
Cardiovascular Screening Practices and Statin Prescription Habits in Patients with Psoriasis among Dermatologists, Rheumatologists and Primary Care Physicians.
Berna-Rico E, Abbad-Jaime de Aragon C, Garcia-Aparicio A, Palacios-Martinez D, Ballester-Martinez A, Carrascosa JM, De la Cueva P, Anton C, Azcarraga-Llobet C, Garcia-Mouronte E, De Nicolas-Ruanes B, Puig L, Jaen P, Mehta NN, Gelfand JM, Gonzalez-Cantero A. Berna-Rico E, et al. Among authors: mehta nn. Acta Derm Venereol. 2023 Mar 28;103:adv5087. doi: 10.2340/actadv.v103.5087. Acta Derm Venereol. 2023. PMID: 36987537 Free PMC article.
Deep-Learning for Epicardial Adipose Tissue Assessment With Computed Tomography: Implications for Cardiovascular Risk Prediction.
West HW, Siddique M, Williams MC, Volpe L, Desai R, Lyasheva M, Thomas S, Dangas K, Kotanidis CP, Tomlins P, Mahon C, Kardos A, Adlam D, Graby J, Rodrigues JCL, Shirodaria C, Deanfield J, Mehta NN, Neubauer S, Channon KM, Desai MY, Nicol ED, Newby DE, Antoniades C; ORFAN Investigators. West HW, et al. Among authors: mehta nn. JACC Cardiovasc Imaging. 2023 Jun;16(6):800-816. doi: 10.1016/j.jcmg.2022.11.018. Epub 2023 Feb 8. JACC Cardiovasc Imaging. 2023. PMID: 36881425 Free PMC article.
DeepHeartCT: A fully automatic artificial intelligence hybrid framework based on convolutional neural network and multi-atlas segmentation for multi-structure cardiac computed tomography angiography image segmentation.
Bui V, Hsu LY, Chang LC, Sun AY, Tran L, Shanbhag SM, Zhou W, Mehta NN, Chen MY. Bui V, et al. Among authors: mehta nn. Front Artif Intell. 2022 Nov 22;5:1059007. doi: 10.3389/frai.2022.1059007. eCollection 2022. Front Artif Intell. 2022. PMID: 36483981 Free PMC article.
Association of Apremilast With Vascular Inflammation and Cardiometabolic Function in Patients With Psoriasis: The VIP-A Phase 4, Open-label, Nonrandomized Clinical Trial.
Gelfand JM, Shin DB, Armstrong AW, Tyring SK, Blauvelt A, Gottlieb S, Lockshin BN, Kalb RE, Fitzsimmons R, Rodante J, Parel P, Manyak GA, Mendelsohn L, Noe MH, Papadopoulos M, Syed MN, Werner TJ, Wan J, Playford MP, Alavi A, Mehta NN. Gelfand JM, et al. Among authors: mehta nn. JAMA Dermatol. 2022 Dec 1;158(12):1394-1403. doi: 10.1001/jamadermatol.2022.3862. JAMA Dermatol. 2022. PMID: 36129688 Free PMC article. Clinical Trial.
Anakinra for refractory pustular psoriasis: A phase II, open-label, dose-escalation trial.
Naik HB, Pichard DC, Schwartz DM, O'Brien M, Masciocchi M, Thompson J, Sen HN, Steinberg SM, Mitchell SA, de Jesus AA, McCalmont TH, Dey A, Rosenstein RK, Deng Z, Goldbach-Mansky R, Mehta NN, Cowen EW. Naik HB, et al. Among authors: mehta nn. J Am Acad Dermatol. 2022 Dec;87(6):1380-1383. doi: 10.1016/j.jaad.2022.07.065. Epub 2022 Sep 16. J Am Acad Dermatol. 2022. PMID: 36116584 Free PMC article. Clinical Trial. No abstract available.
Association of the triglyceride glucose index with insulin resistance and subclinical atherosclerosis in psoriasis: An observational cohort study.
O'Hagan R, Gonzalez-Cantero A, Patel N, Hong CG, Berg AR, Li H, Parel PM, Kapoor P, Rodante JA, Keel A, Chen MY, Zhou W, Playford MP, Teague HL, Sorokin AV, Mehta NN. O'Hagan R, et al. Among authors: mehta nn. J Am Acad Dermatol. 2023 May;88(5):1131-1134. doi: 10.1016/j.jaad.2022.08.027. Epub 2022 Aug 19. J Am Acad Dermatol. 2023. PMID: 35995090 No abstract available.
Differential Effect of Dietary Supplementation with a Soybean Oil Enriched in Oleic Acid versus Linoleic Acid on Plasma Lipids and Atherosclerosis in LDLR-Deficient Mice.
Yang ZH, Nill K, Takechi-Haraya Y, Playford MP, Nguyen D, Yu ZX, Pryor M, Tang J, Rojulpote KV, Mehta NN, Wen H, Remaley AT. Yang ZH, et al. Among authors: mehta nn. Int J Mol Sci. 2022 Jul 29;23(15):8385. doi: 10.3390/ijms23158385. Int J Mol Sci. 2022. PMID: 35955518 Free PMC article.
The combined effect of air and transportation noise pollution on atherosclerotic inflammation and risk of cardiovascular disease events.
Osborne MT, Abohashem S, Naddaf N, Abbasi T, Zureigat H, Mezue K, Ghoneem A, Dar T, Cardeiro AJ, Mehta NN, Rajagopalan S, Fayad ZA, Tawakol A. Osborne MT, et al. Among authors: mehta nn. J Nucl Cardiol. 2023 Apr;30(2):665-679. doi: 10.1007/s12350-022-03003-7. Epub 2022 Aug 1. J Nucl Cardiol. 2023. PMID: 35915324 Free PMC article.
Peroxisome proliferator activated receptor-γ agonist pioglitazone improves vascular and metabolic dysfunction in systemic lupus erythematosus.
Hasni S, Temesgen-Oyelakin Y, Davis M, Chu J, Poncio E, Naqi M, Gupta S, Wang X, Oliveira C, Claybaugh D, Dey A, Lu S, Carlucci P, Purmalek M, Manna ZG, Shi Y, Ochoa-Navas I, Chen J, Mukherjee A, Han KL, Cheung F, Koroleva G, Belkaid Y, Tsang JS, Apps R, Thomas DE, Heller T, Gadina M, Playford MP, Li X, Mehta NN, Kaplan MJ. Hasni S, et al. Among authors: mehta nn. Ann Rheum Dis. 2022 Aug 1;81(11):1576-84. doi: 10.1136/ard-2022-222658. Online ahead of print. Ann Rheum Dis. 2022. PMID: 35914929 Free PMC article.
Association of S100A8/A9 with Lipid-Rich Necrotic Core and Treatment with Biologic Therapy in Patients with Psoriasis: Results from an Observational Cohort Study.
Berg AR, Hong CG, Svirydava M, Li H, Parel PM, Florida E, O'Hagan R, Pantoja CJ, Lateef SS, Anzenberg P, Harrington CL, Ward G, Zhou W, Sorokin AV, Chen MY, Teague HL, Buckler AJ, Playford MP, Gelfand JM, Mehta NN. Berg AR, et al. Among authors: mehta nn. J Invest Dermatol. 2022 Nov;142(11):2909-2919. doi: 10.1016/j.jid.2022.05.1085. Epub 2022 Jun 21. J Invest Dermatol. 2022. PMID: 35750149 Free article.
PET/CT-Based Characterization of 18F-FDG Uptake in Various Tissues Reveals Novel Potential Contributions to Coronary Artery Disease in Psoriatic Arthritis.
Schwartz DM, Parel P, Li H, Sorokin AV, Berg AR, Chen M, Dey A, Hong CG, Playford M, Sylvester M, Teague H, Siegel E, Mehta NN. Schwartz DM, et al. Among authors: mehta nn. Front Immunol. 2022 Jun 2;13:909760. doi: 10.3389/fimmu.2022.909760. eCollection 2022. Front Immunol. 2022. PMID: 35720288 Free PMC article.
Is It Prime Time for Statin Therapy in Psoriasis?
Mehta NN, Gelfand JM. Mehta NN, et al. J Invest Dermatol. 2022 Jun;142(6):1519-1522. doi: 10.1016/j.jid.2022.02.020. J Invest Dermatol. 2022. PMID: 35598898 Free article. No abstract available.
Complex association of apolipoprotein E-containing HDL with coronary artery disease burden in cardiovascular disease.
Sorokin AV, Patel N, Abdelrahman KM, Ling C, Reimund M, Graziano G, Sampson M, Playford MP, Dey AK, Reddy A, Teague HL, Stagliano M, Amar M, Chen MY, Mehta NN, Remaley AT. Sorokin AV, et al. Among authors: mehta nn. JCI Insight. 2022 May 23;7(10):e159577. doi: 10.1172/jci.insight.159577. JCI Insight. 2022. PMID: 35389891 Free PMC article.
Inflammation, coronary plaque progression, and statin use: A secondary analysis of the Risk Stratification with Image Guidance of HMG CoA Reductase Inhibitor Therapy (RIGHT) study.
Scott C, Lateef SS, Hong CG, Dey AK, Manyak GA, Patel NH, Zhou W, Sorokin AV, Abdelrahman K, Uceda D, Teklu M, Wu C, Parel PM, Sandfort V, Chen MY, Mallek M, Ahlman M, Bluemke D, Mehta NN. Scott C, et al. Among authors: mehta nn. Clin Cardiol. 2022 Jun;45(6):622-628. doi: 10.1002/clc.23808. Epub 2022 Apr 2. Clin Cardiol. 2022. PMID: 35366378 Free PMC article.
Inflammatory bowel disease and atherosclerotic cardiovascular disease in U.S. adults-A population-level analysis in the national health interview survey.
Nasir K, Acquah I, Dey AK, Agrawal T, Hassan SZ, Glassner K, Abraham B, Quigley EMM, Blankstein R, Virani SS, Blaha MJ, Valero-Elizondo J, Cainzos-Achirica M, Mehta NN. Nasir K, et al. Among authors: mehta nn. Am J Prev Cardiol. 2022 Jan 17;9:100316. doi: 10.1016/j.ajpc.2022.100316. eCollection 2022 Mar. Am J Prev Cardiol. 2022. PMID: 35112094 Free PMC article.
Viewing Psoriasis as a Systemic Disease for Better Health Outcomes.
Gondo GC, Koons S, Metcalf C, Bell SJ, Mehta NN. Gondo GC, et al. Among authors: mehta nn. JID Innov. 2021 Mar 4;1(2):100007. doi: 10.1016/j.xjidi.2021.100007. eCollection 2021 Jun. JID Innov. 2021. PMID: 34909711 Free PMC article. No abstract available.
Abdominal Visceral Adiposity Is Associated with Coronary Artery Plaque Lipid-Rich Necrotic Core Partly Mediated by Bone Marrow Uptake of 18F-FDG Positron Emission Tomography/Computed Tomography in Psoriasis.
Manyak GA, Patel NH, Dey AK, Svirydava M, Parel PM, Teague HL, Sorokin AV, Teklu M, Zhou W, Playford MP, Mehta NN. Manyak GA, et al. Among authors: mehta nn. J Invest Dermatol. 2022 Jul;142(7):2030-2033.e1. doi: 10.1016/j.jid.2021.10.031. Epub 2021 Nov 29. J Invest Dermatol. 2022. PMID: 34856205 Free article. No abstract available.
Heightened splenic and bone marrow uptake of 18F-FDG PET/CT is associated with systemic inflammation and subclinical atherosclerosis by CCTA in psoriasis: An observational study.
Patel NH, Osborne MT, Teague H, Parel P, Svirydava M, Sorokin AV, Teklu M, Manyak G, Zhou W, Pantoja C, Scott C, Playford MP, Kapoor P, Rodante JA, Keel A, Chen M, Tawakol A, Mehta NN. Patel NH, et al. Among authors: mehta nn. Atherosclerosis. 2021 Dec;339:20-26. doi: 10.1016/j.atherosclerosis.2021.11.008. Epub 2021 Nov 8. Atherosclerosis. 2021. PMID: 34808541 Free PMC article.
Autocrine vitamin D signaling switches off pro-inflammatory programs of TH1 cells.
Chauss D, Freiwald T, McGregor R, Yan B, Wang L, Nova-Lamperti E, Kumar D, Zhang Z, Teague H, West EE, Vannella KM, Ramos-Benitez MJ, Bibby J, Kelly A, Malik A, Freeman AF, Schwartz DM, Portilla D, Chertow DS, John S, Lavender P, Kemper C, Lombardi G, Mehta NN, Cooper N, Lionakis MS, Laurence A, Kazemian M, Afzali B. Chauss D, et al. Among authors: mehta nn. Nat Immunol. 2022 Jan;23(1):62-74. doi: 10.1038/s41590-021-01080-3. Epub 2021 Nov 11. Nat Immunol. 2022. PMID: 34764490 Free PMC article.
The relationship between systemic inflammation and increased left ventricular mass is partly mediated by noncalcified coronary artery disease burden in psoriasis.
Zhou W, Teklu M, Bui V, Manyak GA, Kapoor P, Dey AK, Sorokin AV, Patel N, Teague HL, Playford MP, Erb-Alvarez J, Rodante JA, Keel A, Shanbhag SM, Hsu LY, Bluemke DA, Chen MY, Carlsson M, Mehta NN. Zhou W, et al. Among authors: mehta nn. Am J Prev Cardiol. 2021 May 30;7:100211. doi: 10.1016/j.ajpc.2021.100211. eCollection 2021 Sep. Am J Prev Cardiol. 2021. PMID: 34611643 Free PMC article.
Abdominal subcutaneous adipose tissue negatively associates with subclinical coronary artery disease in men with psoriasis.
Teklu M, Zhou W, Kapoor P, Patel N, Playford MP, Sorokin AV, Dey AK, Teague HL, Manyak GA, Rodante JA, Keel A, Chen MY, Bluemke DA, Khera AV, Mehta NN. Teklu M, et al. Among authors: mehta nn. Am J Prev Cardiol. 2021 Aug 22;8:100231. doi: 10.1016/j.ajpc.2021.100231. eCollection 2021 Dec. Am J Prev Cardiol. 2021. PMID: 34553185 Free PMC article.
Cytokine responses in nonlesional psoriatic skin as clinical predictor to anti-TNF agents.
Tsoi LC, Patrick MT, Shuai S, Sarkar MK, Chi S, Ruffino B, Billi AC, Xing X, Uppala R, Zang C, Fullmer J, He Z, Maverakis E, Mehta NN, Perez White BE, Getsios S, Helfrich Y, Voorhees JJ, Kahlenberg JM, Weidinger S, Gudjonsson JE. Tsoi LC, et al. Among authors: mehta nn. J Allergy Clin Immunol. 2022 Feb;149(2):640-649.e5. doi: 10.1016/j.jaci.2021.07.024. Epub 2021 Jul 31. J Allergy Clin Immunol. 2022. PMID: 34343561 Free PMC article.
Subclinical Liver Disease Is Associated with Subclinical Atherosclerosis in Psoriasis: Results from Two Observational Studies.
Gonzalez-Cantero A, Teklu M, Sorokin AV, Prussick R, González-Cantero J, Martin-Rodriguez JL, Patel N, Parel PM, Manyak GA, Teague HL, Rodante JA, Keel A, Pérez-Hortet C, Sanchéz-Moya AI, Jiménez N, Ballester A, Solis J, Fernandez-Friera L, Barderas MG, Gonzalez-Calvin JL, Jaen P, Playford MP, Dey AK, Gelfand JM, Mehta NN. Gonzalez-Cantero A, et al. Among authors: mehta nn. J Invest Dermatol. 2022 Jan;142(1):88-96. doi: 10.1016/j.jid.2021.05.034. Epub 2021 Jul 19. J Invest Dermatol. 2022. PMID: 34293354 Free article.
Geospatial Analysis of Neighborhood Environmental Stress in Relation to Biological Markers of Cardiovascular Health and Health Behaviors in Women: Protocol for a Pilot Study.
Tamura K, Curlin K, Neally SJ, Vijayakumar NP, Mitchell VM, Collins BS, Gutierrez-Huerta C, Troendle JF, Baumer Y, Osei Baah F, Turner BS, Gray V, Tirado BA, Ortiz-Chaparro E, Berrigan D, Mehta NN, Vaccarino V, Zenk SN, Powell-Wiley TM. Tamura K, et al. Among authors: mehta nn. JMIR Res Protoc. 2021 Jul 22;10(7):e29191. doi: 10.2196/29191. JMIR Res Protoc. 2021. PMID: 34292168 Free PMC article.
A neurobiological link between transportation noise exposure and metabolic disease in humans.
Osborne MT, Naddaf N, Abohashem S, Radfar A, Ghoneem A, Dar T, Wang Y, Patrich T, Oberfeld B, Tung B, Pitman RK, Mehta NN, Shin LM, Lo J, Rajagopalan S, Koenen KC, Grinspoon SK, Fayad ZA, Tawakol A. Osborne MT, et al. Among authors: mehta nn. Psychoneuroendocrinology. 2021 Sep;131:105331. doi: 10.1016/j.psyneuen.2021.105331. Epub 2021 Jun 17. Psychoneuroendocrinology. 2021. PMID: 34183223 Free PMC article.
Sex Differences in Subclinical Coronary Atherosclerosis in Psoriasis by Coronary Computed Tomography Angiography.
Teklu M, Zhou W, Kapoor P, Patel N, Playford MP, Sorokin AV, Dey AK, Teague HL, Abdelrahman KM, Manyak GA, Erb-Alvarez JA, Shanbhag SM, Rodante JA, Keel A, Lockshin B, Chen MY, Gelfand JM, Bluemke DA, Wenger NK, Mehta NN. Teklu M, et al. Among authors: mehta nn. JACC Cardiovasc Imaging. 2021 Oct;14(10):2044-2046. doi: 10.1016/j.jcmg.2021.04.012. Epub 2021 Jun 16. JACC Cardiovasc Imaging. 2021. PMID: 34147437 Free article. No abstract available.
Phase 1 double-blind randomized safety trial of the Janus kinase inhibitor tofacitinib in systemic lupus erythematosus.
Hasni SA, Gupta S, Davis M, Poncio E, Temesgen-Oyelakin Y, Carlucci PM, Wang X, Naqi M, Playford MP, Goel RR, Li X, Biehl AJ, Ochoa-Navas I, Manna Z, Shi Y, Thomas D, Chen J, Biancotto A, Apps R, Cheung F, Kotliarov Y, Babyak AL, Zhou H, Shi R, Stagliano K, Tsai WL, Vian L, Gazaniga N, Giudice V, Lu S, Brooks SR, MacKay M, Gregersen P, Mehta NN, Remaley AT, Diamond B, O'Shea JJ, Gadina M, Kaplan MJ. Hasni SA, et al. Among authors: mehta nn. Nat Commun. 2021 Jun 7;12(1):3391. doi: 10.1038/s41467-021-23361-z. Nat Commun. 2021. PMID: 34099646 Free PMC article. Clinical Trial.
Impact of Biological Agents on Imaging and Biomarkers of Cardiovascular Disease in Patients with Psoriasis: A Systematic Review and Meta-Analysis of Randomized Placebo-Controlled Trials.
González-Cantero A, Ortega-Quijano D, Álvarez-Díaz N, Ballester MA, Jimenez-Gomez N, Jaen P, González-Cantero J, González-Calvin JL, Barderas MG, Shin DB, Mehta NN, Gelfand JM. González-Cantero A, et al. Among authors: mehta nn. J Invest Dermatol. 2021 Oct;141(10):2402-2411. doi: 10.1016/j.jid.2021.03.024. Epub 2021 Apr 21. J Invest Dermatol. 2021. PMID: 33891953 Free article.
The evolving role of coronary CT angiography in Acute Coronary Syndromes.
Kumar V, Weerakoon S, Dey AK, Earls JP, Katz RJ, Reiner JS, Shaw LJ, Blankstein R, Mehta NN, Choi AD. Kumar V, et al. Among authors: mehta nn. J Cardiovasc Comput Tomogr. 2021 Sep-Oct;15(5):384-393. doi: 10.1016/j.jcct.2021.02.002. Epub 2021 Feb 23. J Cardiovasc Comput Tomogr. 2021. PMID: 33858808 Review.
Chronic Stress-Related Neural Activity Associates With Subclinical Cardiovascular Disease in a Community-Based Cohort: Data From the Washington, D.C. Cardiovascular Health and Needs Assessment.
Powell-Wiley TM, Dey AK, Rivers JP, Chaturvedi A, Andrews MR, Ceasar JN, Claudel SE, Mitchell VM, Ayers C, Tamura K, Gutierrez-Huerta CA, Teague HL, Oeser SG, Goyal A, Joshi AA, Collins BS, Baumer Y, Chung ST, Sumner AE, Playford MP, Tawakol A, Mehta NN. Powell-Wiley TM, et al. Among authors: mehta nn. Front Cardiovasc Med. 2021 Mar 10;8:599341. doi: 10.3389/fcvm.2021.599341. eCollection 2021. Front Cardiovasc Med. 2021. PMID: 33778019 Free PMC article.
Fasting-induced FOXO4 blunts human CD4+ T helper cell responsiveness.
Han K, Singh K, Rodman MJ, Hassanzadeh S, Wu K, Nguyen A, Huffstutler RD, Seifuddin F, Dagur PK, Saxena A, McCoy JP, Chen J, Biancotto A, Stagliano KER, Teague HL, Mehta NN, Pirooznia M, Sack MN. Han K, et al. Among authors: mehta nn. Nat Metab. 2021 Mar;3(3):318-326. doi: 10.1038/s42255-021-00356-0. Epub 2021 Mar 15. Nat Metab. 2021. PMID: 33723462 Free PMC article.
Underperformance of clinical risk scores in identifying imaging-based high cardiovascular risk in psoriasis: results from two observational cohorts.
Gonzalez-Cantero A, Reddy AS, Dey AK, Gonzalez-Cantero J, Munger E, Rodante J, Sanchez-Moya AI, Perez-Hortet C, Gonzalez-Calvin JL, Playford MP, Barderas MG, Ballester A, Jimenez-Gomez N, Jaén P, Chen MY, Gelfand JM, Mehta NN. Gonzalez-Cantero A, et al. Among authors: mehta nn. Eur J Prev Cardiol. 2022 Mar 30;29(4):591-598. doi: 10.1093/eurjpc/zwaa033. Eur J Prev Cardiol. 2022. PMID: 33624060
Divergence of Cardiovascular Biomarkers of Lipids and Subclinical Myocardial Injury Among Rheumatoid Arthritis Patients With Increased Inflammation.
Weber B, He Z, Yang N, Playford MP, Weisenfeld D, Iannaccone C, Coblyn J, Weinblatt M, Shadick N, Di Carli M, Mehta NN, Plutzky J, Liao KP. Weber B, et al. Among authors: mehta nn. Arthritis Rheumatol. 2021 Jun;73(6):970-979. doi: 10.1002/art.41613. Epub 2021 May 9. Arthritis Rheumatol. 2021. PMID: 33615723 Free PMC article.
Causal Relationship and Shared Genetic Loci between Psoriasis and Type 2 Diabetes through Trans-Disease Meta-Analysis.
Patrick MT, Stuart PE, Zhang H, Zhao Q, Yin X, He K, Zhou XJ, Mehta NN, Voorhees JJ, Boehnke M, Gudjonsson JE, Nair RP, Handelman SK, Elder JT, Liu DJ, Tsoi LC. Patrick MT, et al. Among authors: mehta nn. J Invest Dermatol. 2021 Jun;141(6):1493-1502. doi: 10.1016/j.jid.2020.11.025. Epub 2020 Dec 30. J Invest Dermatol. 2021. PMID: 33385400 Free PMC article.
Metabolic syndrome and its factors are associated with noncalcified coronary burden in psoriasis: An observational cohort study.
Teklu M, Zhou W, Kapoor P, Patel N, Dey AK, Sorokin AV, Manyak GA, Teague HL, Erb-Alvarez JA, Sajja A, Abdelrahman KM, Reddy AS, Uceda DE, Lateef SS, Shanbhag SM, Scott C, Prakash N, Svirydava M, Parel P, Rodante JA, Keel A, Siegel EL, Chen MY, Bluemke DA, Playford MP, Gelfand JM, Mehta NN. Teklu M, et al. Among authors: mehta nn. J Am Acad Dermatol. 2021 May;84(5):1329-1338. doi: 10.1016/j.jaad.2020.12.044. Epub 2021 Feb 3. J Am Acad Dermatol. 2021. PMID: 33383084
Association Among Noncalcified Coronary Burden, Fractional Flow Reserve, and Myocardial Injury in Psoriasis.
Zhou W, Abdelrahman KM, Dey AK, Reddy A, Uceda DE, Lateef SS, Elnabawi YA, Anzenberg P, Al Najafi M, Rodante JA, Keel A, Ortiz J, Teague HL, Erb-Alvarez J, Singh D, Joshi AA, Playford MP, Chen MY, Gelfand JM, Remaley AT, Bluemke DA, Mehta NN. Zhou W, et al. Among authors: mehta nn. J Am Heart Assoc. 2020 Nov 17;9(22):e017417. doi: 10.1161/JAHA.119.017417. Epub 2020 Nov 10. J Am Heart Assoc. 2020. PMID: 33170072 Free PMC article.
Oxidized Lipids and Lipoprotein Dysfunction in Psoriasis.
Sorokin AV, Remaley AT, Mehta NN. Sorokin AV, et al. Among authors: mehta nn. J Psoriasis Psoriatic Arthritis. 2020 Oct;5(4):139-146. doi: 10.1177/2475530320950268. Epub 2020 Aug 26. J Psoriasis Psoriatic Arthritis. 2020. PMID: 33163854 Free PMC article.
T Cells in Autoimmunity-Associated Cardiovascular Diseases.
Schwartz DM, Burma AM, Kitakule MM, Luo Y, Mehta NN. Schwartz DM, et al. Among authors: mehta nn. Front Immunol. 2020 Oct 7;11:588776. doi: 10.3389/fimmu.2020.588776. eCollection 2020. Front Immunol. 2020. PMID: 33117403 Free PMC article. Review.
Chronic inflammation in psoriasis promotes visceral adiposity associated with noncalcified coronary burden over time.
Sajja A, Abdelrahman KM, Reddy AS, Dey AK, Uceda DE, Lateef SS, Sorokin AV, Teague HL, Chung J, Rivers J, Joshi AA, Elnabawi YA, Goyal A, Rodante JA, Keel A, Alvarez JE, Lockshin B, Prussick R, Siegel E, Playford MP, Chen MY, Bluemke DA, Gelfand JM, Mehta NN. Sajja A, et al. Among authors: mehta nn. JCI Insight. 2020 Nov 19;5(22):e142534. doi: 10.1172/jci.insight.142534. JCI Insight. 2020. PMID: 33104056 Free PMC article.
Impaired Coronary Blood Flow in Patients with Psoriasis: Findings from an Observational Cohort Study.
Uceda DE, Dey AK, Lateef SS, Abdelrahman K, Aksentijevich M, Reddy AS, Choi H, Rodante JA, Playford MP, Bluemke DA, Zhou W, Chen MY, Gelfand JM, Mehta NN. Uceda DE, et al. Among authors: mehta nn. J Invest Dermatol. 2021 Apr;141(4):913-916. doi: 10.1016/j.jid.2020.07.037. Epub 2020 Oct 1. J Invest Dermatol. 2021. PMID: 33011154 Free PMC article. No abstract available.
Macrophage maturation from blood monocytes is altered in people with HIV, and is linked to serum lipid profiles and activation indices: A model for studying atherogenic mechanisms.
Bowman ER, Cameron CM, Richardson B, Kulkarni M, Gabriel J, Cichon MJ, Riedl KM, Mustafa Y, Cartwright M, Snyder B, Raman SV, Zidar DA, Koletar SL, Playford MP, Mehta NN, Sieg SF, Freeman ML, Lederman MM, Cameron MJ, Funderburg NT. Bowman ER, et al. Among authors: mehta nn. PLoS Pathog. 2020 Oct 1;16(10):e1008869. doi: 10.1371/journal.ppat.1008869. eCollection 2020 Oct. PLoS Pathog. 2020. PMID: 33002093 Free PMC article.
Proteomic, biomechanical and functional analyses define neutrophil heterogeneity in systemic lupus erythematosus.
Bashant KR, Aponte AM, Randazzo D, Rezvan Sangsari P, Wood AJ, Bibby JA, West EE, Vassallo A, Manna ZG, Playford MP, Jordan N, Hasni S, Gucek M, Kemper C, Conway Morris A, Morgan NY, Toepfner N, Guck J, Mehta NN, Chilvers ER, Summers C, Kaplan MJ. Bashant KR, et al. Among authors: mehta nn. Ann Rheum Dis. 2021 Feb;80(2):209-218. doi: 10.1136/annrheumdis-2020-218338. Epub 2020 Sep 28. Ann Rheum Dis. 2021. PMID: 32988843 Free PMC article.
Tildrakizumab efficacy, drug survival, and safety are comparable in patients with psoriasis with and without metabolic syndrome: Long-term results from 2 phase 3 randomized controlled studies (reSURFACE 1 and reSURFACE 2).
Lebwohl MG, Leonardi CL, Mehta NN, Gottlieb AB, Mendelsohn AM, Parno J, Rozzo SJ, Menter MA. Lebwohl MG, et al. Among authors: mehta nn. J Am Acad Dermatol. 2021 Feb;84(2):398-407. doi: 10.1016/j.jaad.2020.09.047. Epub 2020 Sep 19. J Am Acad Dermatol. 2021. PMID: 32961255 Free article. Clinical Trial.
Atherosclerotic Plaque Burden on Abdominal CT: Automated Assessment With Deep Learning on Noncontrast and Contrast-enhanced Scans.
Summers RM, Elton DC, Lee S, Zhu Y, Liu J, Bagheri M, Sandfort V, Grayson PC, Mehta NN, Pinto PA, Linehan WM, Perez AA, Graffy PM, O'Connor SD, Pickhardt PJ. Summers RM, et al. Among authors: mehta nn. Acad Radiol. 2021 Nov;28(11):1491-1499. doi: 10.1016/j.acra.2020.08.022. Epub 2020 Sep 18. Acad Radiol. 2021. PMID: 32958429 Free PMC article.
Treatment of Psoriasis With Biologic Therapy Is Associated With Improvement of Coronary Artery Plaque Lipid-Rich Necrotic Core: Results From a Prospective, Observational Study.
Choi H, Uceda DE, Dey AK, Abdelrahman KM, Aksentijevich M, Rodante JA, Elnabawi YA, Reddy A, Keel A, Erb-Alvarez J, Teague H, Playford MP, Zhou W, Chen MY, Gelfand JM, Bluemke DA, Buckler A, Mehta NN. Choi H, et al. Among authors: mehta nn. Circ Cardiovasc Imaging. 2020 Sep;13(9):e011199. doi: 10.1161/CIRCIMAGING.120.011199. Epub 2020 Sep 15. Circ Cardiovasc Imaging. 2020. PMID: 32927971
Coronary Computed Tomography Angiography From Clinical Uses to Emerging Technologies: JACC State-of-the-Art Review.
Abdelrahman KM, Chen MY, Dey AK, Virmani R, Finn AV, Khamis RY, Choi AD, Min JK, Williams MC, Buckler AJ, Taylor CA, Rogers C, Samady H, Antoniades C, Shaw LJ, Budoff MJ, Hoffmann U, Blankstein R, Narula J, Mehta NN. Abdelrahman KM, et al. Among authors: mehta nn. J Am Coll Cardiol. 2020 Sep 8;76(10):1226-1243. doi: 10.1016/j.jacc.2020.06.076. J Am Coll Cardiol. 2020. PMID: 32883417 Free PMC article. Review.
Relationship between chronic stress-related neural activity, physiological dysregulation and coronary artery disease in psoriasis: Findings from a longitudinal observational cohort study.
Lateef SS, Al Najafi M, Dey AK, Batool M, Abdelrahman KM, Uceda DE, Reddy AS, Svirydava MD, Nanda N, Ortiz JE, Prakash N, Rodante JA, Keel A, Zhou W, Chen MY, Playford MP, Teague HL, Tawakol AA, Gelfand JM, Powell-Wiley TM, Mehta NN. Lateef SS, et al. Among authors: mehta nn. Atherosclerosis. 2020 Oct;310:37-44. doi: 10.1016/j.atherosclerosis.2020.07.012. Epub 2020 Jul 29. Atherosclerosis. 2020. PMID: 32882485 Free PMC article.
Disentangling the Links Between Psychosocial Stress and Cardiovascular Disease.
Osborne MT, Shin LM, Mehta NN, Pitman RK, Fayad ZA, Tawakol A. Osborne MT, et al. Among authors: mehta nn. Circ Cardiovasc Imaging. 2020 Aug;13(8):e010931. doi: 10.1161/CIRCIMAGING.120.010931. Epub 2020 Aug 14. Circ Cardiovasc Imaging. 2020. PMID: 32791843 Free PMC article. Review.
An autocrine Vitamin D-driven Th1 shutdown program can be exploited for COVID-19.
McGregor R, Chauss D, Freiwald T, Yan B, Wang L, Nova-Lamperti E, Zhang Z, Teague H, West EE, Bibby J, Kelly A, Malik A, Freeman AF, Schwartz D, Portilla D, John S, Lavender P, Lionakis MS, Mehta NN, Kemper C, Cooper N, Lombardi G, Laurence A, Kazemian M, Afzali B. McGregor R, et al. Among authors: mehta nn. bioRxiv [Preprint]. 2020 Jul 19:2020.07.18.210161. doi: 10.1101/2020.07.18.210161. bioRxiv. 2020. PMID: 32743590 Free PMC article. Preprint.
Joint AAD-NPF Guidelines of care for the management and treatment of psoriasis with topical therapy and alternative medicine modalities for psoriasis severity measures.
Elmets CA, Korman NJ, Prater EF, Wong EB, Rupani RN, Kivelevitch D, Armstrong AW, Connor C, Cordoro KM, Davis DMR, Elewski BE, Gelfand JM, Gordon KB, Gottlieb AB, Kaplan DH, Kavanaugh A, Kiselica M, Kroshinsky D, Lebwohl M, Leonardi CL, Lichten J, Lim HW, Mehta NN, Paller AS, Parra SL, Pathy AL, Siegel M, Stoff B, Strober B, Wu JJ, Hariharan V, Menter A. Elmets CA, et al. Among authors: mehta nn. J Am Acad Dermatol. 2021 Feb;84(2):432-470. doi: 10.1016/j.jaad.2020.07.087. Epub 2020 Jul 30. J Am Acad Dermatol. 2021. PMID: 32738429
Neighborhood environment perceptions associate with depression levels and cardiovascular risk among middle-aged and older adults: Data from the Washington, DC cardiovascular health and needs assessment.
Andrews MR, Ceasar J, Tamura K, Langerman SD, Mitchell VM, Collins BS, Baumer Y, Gutierrez Huerta CA, Dey AK, Playford MP, Mehta NN, Powell-Wiley TM. Andrews MR, et al. Among authors: mehta nn. Aging Ment Health. 2021 Nov;25(11):2078-2089. doi: 10.1080/13607863.2020.1793898. Epub 2020 Jul 21. Aging Ment Health. 2021. PMID: 32691611 Free PMC article.
Hyperlipidaemia and IFNgamma/TNFalpha Synergism are associated with cholesterol crystal formation in Endothelial cells partly through modulation of Lysosomal pH and Cholesterol homeostasis.
Baumer Y, Dey AK, Gutierrez-Huerta CA, Khalil NO, Sekine Y, Sanda GE, Zhuang J, Saxena A, Stempinski E, Elnabawi YA, Dagur PK, Ng Q, Teague HL, Keel A, Rodante JA, Boisvert WA, Tsoi LC, Gudjonsson JE, Bleck CKE, Chen MY, Bluemke DA, Gelfand JM, Schwartz DM, Kruth HS, Powell-Wiley TM, Playford MP, Mehta NN. Baumer Y, et al. Among authors: mehta nn. EBioMedicine. 2020 Sep;59:102876. doi: 10.1016/j.ebiom.2020.102876. Epub 2020 Jul 6. EBioMedicine. 2020. PMID: 32646751 Free PMC article.
Role of Periodontal Infection, Inflammation and Immunity in Atherosclerosis.
Choi H, Dey AK, Priyamvara A, Aksentijevich M, Bandyopadhyay D, Dey D, Dani S, Guha A, Nambiar P, Nasir K, Jneid H, Mehta NN, Lavie CJ, Amar S. Choi H, et al. Among authors: mehta nn. Curr Probl Cardiol. 2021 Mar;46(3):100638. doi: 10.1016/j.cpcardiol.2020.100638. Epub 2020 Jun 4. Curr Probl Cardiol. 2021. PMID: 32646544 Free PMC article. Review.
Characterization of PCSK9 in the Blood and Skin of Psoriasis.
Garshick MS, Baumer Y, Dey AK, Grattan R, Ng Q, Teague HL, Yu ZX, Chen MY, Tawil M, Barrett TJ, Underberg J, Fisher EA, Krueger J, Powell-Wiley TM, Playford MP, Berger JS, Mehta NN. Garshick MS, et al. Among authors: mehta nn. J Invest Dermatol. 2021 Feb;141(2):308-315. doi: 10.1016/j.jid.2020.05.115. Epub 2020 Jun 29. J Invest Dermatol. 2021. PMID: 32615123 Free PMC article.
Cholesterol crystals and atherosclerosis.
Baumer Y, Mehta NN, Dey AK, Powell-Wiley TM, Boisvert WA. Baumer Y, et al. Among authors: mehta nn. Eur Heart J. 2020 Jun 21;41(24):2236-2239. doi: 10.1093/eurheartj/ehaa505. Eur Heart J. 2020. PMID: 32572475 Free PMC article. No abstract available.
Comparison of Omega-3 Eicosapentaenoic Acid Versus Docosahexaenoic Acid-Rich Fish Oil Supplementation on Plasma Lipids and Lipoproteins in Normolipidemic Adults.
Yang ZH, Amar M, Sampson M, Courville AB, Sorokin AV, Gordon SM, Aponte AM, Stagliano M, Playford MP, Fu YP, Yang S, Mehta NN, Remaley AT. Yang ZH, et al. Among authors: mehta nn. Nutrients. 2020 Mar 12;12(3):749. doi: 10.3390/nu12030749. Nutrients. 2020. PMID: 32178279 Free PMC article. Clinical Trial.
Activated Platelets Induce Endothelial Cell Inflammatory Response in Psoriasis via COX-1.
Garshick MS, Tawil M, Barrett TJ, Salud-Gnilo CM, Eppler M, Lee A, Scher JU, Neimann AL, Jelic S, Mehta NN, Fisher EA, Krueger JG, Berger JS. Garshick MS, et al. Among authors: mehta nn. Arterioscler Thromb Vasc Biol. 2020 May;40(5):1340-1351. doi: 10.1161/ATVBAHA.119.314008. Epub 2020 Mar 5. Arterioscler Thromb Vasc Biol. 2020. PMID: 32131611 Free PMC article. Clinical Trial.
Joint American Academy of Dermatology-National Psoriasis Foundation guidelines of care for the management of psoriasis with systemic nonbiologic therapies.
Menter A, Gelfand JM, Connor C, Armstrong AW, Cordoro KM, Davis DMR, Elewski BE, Gordon KB, Gottlieb AB, Kaplan DH, Kavanaugh A, Kiselica M, Kivelevitch D, Korman NJ, Kroshinsky D, Lebwohl M, Leonardi CL, Lichten J, Lim HW, Mehta NN, Paller AS, Parra SL, Pathy AL, Prater EF, Rahimi RS, Rupani RN, Siegel M, Stoff B, Strober BE, Tapper EB, Wong EB, Wu JJ, Hariharan V, Elmets CA. Menter A, et al. Among authors: mehta nn. J Am Acad Dermatol. 2020 Jun;82(6):1445-1486. doi: 10.1016/j.jaad.2020.02.044. Epub 2020 Feb 28. J Am Acad Dermatol. 2020. PMID: 32119894
A Randomized Placebo-Controlled Trial of Secukinumab on Aortic Vascular Inflammation in Moderate-to-Severe Plaque Psoriasis (VIP-S).
Gelfand JM, Shin DB, Duffin KC, Armstrong AW, Blauvelt A, Tyring SK, Menter A, Gottlieb S, Lockshin BN, Simpson EL, Kianifard F, Sarkar RP, Muscianisi E, Steadman J, Ahlman MA, Playford MP, Joshi AA, Dey AK, Werner TJ, Alavi A, Mehta NN. Gelfand JM, et al. Among authors: mehta nn. J Invest Dermatol. 2020 Sep;140(9):1784-1793.e2. doi: 10.1016/j.jid.2020.01.025. Epub 2020 Feb 21. J Invest Dermatol. 2020. PMID: 32088207 Free PMC article. Clinical Trial.
Immune cell phenotyping in low blood volumes for assessment of cardiovascular disease risk, development, and progression: a pilot study.
Baumer Y, Gutierrez-Huerta CA, Saxena A, Dagur PK, Langerman SD, Tamura K, Ceasar JN, Andrews MR, Mitchell V, Collins BS, Yu Q, Teague HL, Playford MP, Bleck CKE, Mehta NN, McCoy JP, Powell-Wiley TM. Baumer Y, et al. Among authors: mehta nn. J Transl Med. 2020 Jan 17;18(1):29. doi: 10.1186/s12967-020-02207-0. J Transl Med. 2020. PMID: 31952533 Free PMC article.
The mechanics of myeloid cells.
Bashant KR, Toepfner N, Day CJ, Mehta NN, Kaplan MJ, Summers C, Guck J, Chilvers ER. Bashant KR, et al. Among authors: mehta nn. Biol Cell. 2020 Apr;112(4):103-112. doi: 10.1111/boc.201900084. Epub 2020 Jan 20. Biol Cell. 2020. PMID: 31916263 Review.
Supplementation with saury oil, a fish oil high in omega-11 monounsaturated fatty acids, improves plasma lipids in healthy subjects.
Yang ZH, Amar M, Sorokin AV, Troendle J, Courville AB, Sampson M, Playford MP, Yang S, Stagliano M, Ling C, Donkor K, Shamburek RD, Mehta NN, Remaley AT. Yang ZH, et al. Among authors: mehta nn. J Clin Lipidol. 2020 Jan-Feb;14(1):53-65.e2. doi: 10.1016/j.jacl.2019.10.013. Epub 2019 Oct 31. J Clin Lipidol. 2020. PMID: 31784345 Free PMC article. Clinical Trial.
Transcriptomic, epigenetic, and functional analyses implicate neutrophil diversity in the pathogenesis of systemic lupus erythematosus.
Mistry P, Nakabo S, O'Neil L, Goel RR, Jiang K, Carmona-Rivera C, Gupta S, Chan DW, Carlucci PM, Wang X, Naz F, Manna Z, Dey A, Mehta NN, Hasni S, Dell'Orso S, Gutierrez-Cruz G, Sun HW, Kaplan MJ. Mistry P, et al. Among authors: mehta nn. Proc Natl Acad Sci U S A. 2019 Dec 10;116(50):25222-25228. doi: 10.1073/pnas.1908576116. Epub 2019 Nov 21. Proc Natl Acad Sci U S A. 2019. PMID: 31754025 Free PMC article.
PCSK9 inhibition as a novel therapeutic target for alcoholic liver disease.
Lee JS, Mukhopadhyay P, Matyas C, Trojnar E, Paloczi J, Yang YR, Blank BA, Savage C, Sorokin AV, Mehta NN, Vendruscolo JCM, Koob GF, Vendruscolo LF, Pacher P, Lohoff FW. Lee JS, et al. Among authors: mehta nn. Sci Rep. 2019 Nov 20;9(1):17167. doi: 10.1038/s41598-019-53603-6. Sci Rep. 2019. PMID: 31748600 Free PMC article.
Association Between Soluble Lectinlike Oxidized Low-Density Lipoprotein Receptor-1 and Coronary Artery Disease in Psoriasis.
Dey AK, Gaddipati R, Elnabawi YA, Ongstad E, Goyal A, Chung JH, Teague HL, Rodante JA, Sajja AA, Sorokin AV, Lateef SS, Aksentijevich M, Choi H, Reddy AS, Varghese NJ, Groenendyk J, Belur AD, Genovese L, Rivers JP, Lerman J, Kabbany MT, Harrington C, Ortiz J, Khalil N, Keel A, Baumer Y, Chen MY, Bluemke DA, Joshi AA, Kaplan MJ, Remaley AT, Playford MP, Karathanasis SK, Gelfand JM, Gupta R, Mehta NN. Dey AK, et al. Among authors: mehta nn. JAMA Dermatol. 2020 Feb 1;156(2):151-157. doi: 10.1001/jamadermatol.2019.3595. JAMA Dermatol. 2020. PMID: 31746956 Free PMC article.
Psoriasis and Mental Health Workshop Report: Exploring the Links between Psychosocial Factors, Psoriasis, Neuroinflammation and Cardiovascular Disease Risk.
Kleyn CE, Talbot PS, Mehta NN, Sampogna F, Bundy C, Ashcroft DM, Kimball AB, van de Kerkhof PCM, Griffiths CEM, Valenzuela F, van der Walt JM, Aberra T, Puig L. Kleyn CE, et al. Among authors: mehta nn. Acta Derm Venereol. 2020 Jan 7;100(1):adv00020. doi: 10.2340/00015555-3375. Acta Derm Venereol. 2020. PMID: 31742649 Free PMC article. Review.
Joint American Academy of Dermatology-National Psoriasis Foundation guidelines of care for the management and treatment of psoriasis in pediatric patients.
Menter A, Cordoro KM, Davis DMR, Kroshinsky D, Paller AS, Armstrong AW, Connor C, Elewski BE, Gelfand JM, Gordon KB, Gottlieb AB, Kaplan DH, Kavanaugh A, Kiselica M, Kivelevitch D, Korman NJ, Lebwohl M, Leonardi CL, Lichten J, Lim HW, Mehta NN, Parra SL, Pathy AL, Farley Prater EA, Rupani RN, Siegel M, Stoff B, Strober BE, Wong EB, Wu JJ, Hariharan V, Elmets CA. Menter A, et al. Among authors: mehta nn. J Am Acad Dermatol. 2020 Jan;82(1):161-201. doi: 10.1016/j.jaad.2019.08.049. Epub 2019 Nov 5. J Am Acad Dermatol. 2020. PMID: 31703821
Application of machine learning to determine top predictors of noncalcified coronary burden in psoriasis: An observational cohort study.
Munger E, Choi H, Dey AK, Elnabawi YA, Groenendyk JW, Rodante J, Keel A, Aksentijevich M, Reddy AS, Khalil N, Argueta-Amaya J, Playford MP, Erb-Alvarez J, Tian X, Wu C, Gudjonsson JE, Tsoi LC, Jafri MS, Sandfort V, Chen MY, Shah SJ, Bluemke DA, Lockshin B, Hasan A, Gelfand JM, Mehta NN. Munger E, et al. Among authors: mehta nn. J Am Acad Dermatol. 2020 Dec;83(6):1647-1653. doi: 10.1016/j.jaad.2019.10.060. Epub 2019 Oct 31. J Am Acad Dermatol. 2020. PMID: 31678339 Free PMC article.
Tildrakizumab efficacy and safety are not altered by metabolic syndrome status in patients with psoriasis: Post hoc analysis of 2 phase 3 randomized controlled studies (reSURFACE 1 and reSURFACE 2).
Lebwohl MG, Leonardi CL, Mehta NN, Gottlieb AB, Mendelsohn AM, Parno J, Rozzo SJ, Menter A. Lebwohl MG, et al. Among authors: mehta nn. J Am Acad Dermatol. 2020 Feb;82(2):519-522. doi: 10.1016/j.jaad.2019.09.042. Epub 2019 Sep 26. J Am Acad Dermatol. 2020. PMID: 31563641 Free article. No abstract available.
Cells of Myeloid Origin Partly Mediate the Association between Psoriasis Severity and Coronary Plaque.
Teague HL, Aksentijevich M, Stansky E, Silverman JI, Varghese NJ, Dey AK, Elnabawi Y, Goyal A, Dagur PK, Chen MY, McCoy JP, Playford MP, Hourigan C, Gelfand JM, Mehta NN. Teague HL, et al. Among authors: mehta nn. J Invest Dermatol. 2020 Apr;140(4):912-915.e1. doi: 10.1016/j.jid.2019.07.724. Epub 2019 Sep 17. J Invest Dermatol. 2020. PMID: 31539534 Free PMC article. No abstract available.
Serum active 1,25(OH)2D, but not inactive 25(OH)D vitamin D levels are associated with cardiometabolic and cardiovascular disease risk in psoriasis.
Playford MP, Dey AK, Zierold C, Joshi AA, Blocki F, Bonelli F, Rodante JA, Harrington CL, Rivers JP, Elnabawi YA, Chen MY, Ahlman MA, Teague HL, Mehta NN. Playford MP, et al. Among authors: mehta nn. Atherosclerosis. 2019 Oct;289:44-50. doi: 10.1016/j.atherosclerosis.2019.08.006. Epub 2019 Aug 17. Atherosclerosis. 2019. PMID: 31450013 Free PMC article.
Association of lipoprotein subfractions and glycoprotein acetylation with coronary plaque burden in SLE.
Purmalek MM, Carlucci PM, Dey AK, Sampson M, Temesgen-Oyelakin Y, Sakhardande S, Lerman JB, Fike A, Davis M, Chung JH, Salahuddin T, Manna Z, Gupta S, Chen MY, Hasni S, Mehta NN, Remaley A, Kaplan MJ. Purmalek MM, et al. Among authors: mehta nn. Lupus Sci Med. 2019 Jul 12;6(1):e000332. doi: 10.1136/lupus-2019-000332. eCollection 2019. Lupus Sci Med. 2019. PMID: 31413851 Free PMC article.
Association of aortic vascular uptake of 18FDG by PET/CT and aortic wall thickness by MRI in psoriasis: a prospective observational study.
Groenendyk JW, Shukla P, Dey AK, Elnabawi YA, Aksentijevich M, Choi H, Genovese LD, Harrington CL, Natarajan B, Goyal A, Reddy AS, Rodante J, Kabbany MT, Sadek A, Al Najafi M, Playford MP, Joshi AA, Ahlman MA, Gelfand JM, Bluemke DA, Mehta NN. Groenendyk JW, et al. Among authors: mehta nn. Eur J Nucl Med Mol Imaging. 2019 Nov;46(12):2488-2495. doi: 10.1007/s00259-019-04454-w. Epub 2019 Aug 5. Eur J Nucl Med Mol Imaging. 2019. PMID: 31385013 Free PMC article.
Association of Biologic Therapy With Coronary Inflammation in Patients With Psoriasis as Assessed by Perivascular Fat Attenuation Index.
Elnabawi YA, Oikonomou EK, Dey AK, Mancio J, Rodante JA, Aksentijevich M, Choi H, Keel A, Erb-Alvarez J, Teague HL, Joshi AA, Playford MP, Lockshin B, Choi AD, Gelfand JM, Chen MY, Bluemke DA, Shirodaria C, Antoniades C, Mehta NN. Elnabawi YA, et al. Among authors: mehta nn. JAMA Cardiol. 2019 Sep 1;4(9):885-891. doi: 10.1001/jamacardio.2019.2589. JAMA Cardiol. 2019. PMID: 31365032 Free PMC article.
Joint American Academy of Dermatology-National Psoriasis Foundation guidelines of care for the management and treatment of psoriasis with phototherapy.
Elmets CA, Lim HW, Stoff B, Connor C, Cordoro KM, Lebwohl M, Armstrong AW, Davis DMR, Elewski BE, Gelfand JM, Gordon KB, Gottlieb AB, Kaplan DH, Kavanaugh A, Kiselica M, Kivelevitch D, Korman NJ, Kroshinsky D, Leonardi CL, Lichten J, Mehta NN, Paller AS, Parra SL, Pathy AL, Farley Prater EA, Rupani RN, Siegel M, Strober BE, Wong EB, Wu JJ, Hariharan V, Menter A. Elmets CA, et al. Among authors: mehta nn. J Am Acad Dermatol. 2019 Sep;81(3):775-804. doi: 10.1016/j.jaad.2019.04.042. Epub 2019 Jul 25. J Am Acad Dermatol. 2019. PMID: 31351884
A Phase IV, Randomized, Double-Blind, Placebo-Controlled Crossover Study of the Effects of Ustekinumab on Vascular Inflammation in Psoriasis (the VIP-U Trial).
Gelfand JM, Shin DB, Alavi A, Torigian DA, Werner T, Papadopoulos M, Takeshita J, Noe MH, Dey AK, Playford MP, Mehta NN. Gelfand JM, et al. Among authors: mehta nn. J Invest Dermatol. 2020 Jan;140(1):85-93.e2. doi: 10.1016/j.jid.2019.07.679. Epub 2019 Jul 19. J Invest Dermatol. 2020. PMID: 31326395 Free PMC article. Clinical Trial.
Patient-reported outcomes of adalimumab, phototherapy, and placebo in the Vascular Inflammation in Psoriasis Trial: A randomized controlled study.
Noe MH, Wan MT, Shin DB, Armstrong AW, Duffin KC, Chiesa Fuxench ZC, Kalb RE, Menter A, Simpson EL, Takeshita J, Tyring SK, Van Voorhees AS, Mehta NN, Gelfand JM. Noe MH, et al. Among authors: mehta nn. J Am Acad Dermatol. 2019 Oct;81(4):923-930. doi: 10.1016/j.jaad.2019.05.080. Epub 2019 Jun 1. J Am Acad Dermatol. 2019. PMID: 31163241 Free PMC article. Clinical Trial.
Cardiovascular Diseases in Psoriasis and Psoriatic Arthritis.
Eder L, Dey A, Joshi AA, Boehncke WH, Mehta NN, Szentpetery A. Eder L, et al. Among authors: mehta nn. J Rheumatol Suppl. 2019 Jun;95:20-27. doi: 10.3899/jrheum.190114. J Rheumatol Suppl. 2019. PMID: 31154400
Biologic therapy to treat Psoriasis: A Dual Benefit?
Joshi AA, Mehta NN. Joshi AA, et al. Among authors: mehta nn. Eur Heart J. 2019 Jun 1;40(21):1670. doi: 10.1093/eurheartj/ehz349. Eur Heart J. 2019. PMID: 31152548 Free PMC article. No abstract available.
Neutrophil Subsets, Platelets, and Vascular Disease in Psoriasis.
Teague HL, Varghese NJ, Tsoi LC, Dey AK, Garshick MS, Silverman JI, Baumer Y, Harrington CL, Stempinski E, Elnabawi YA, Dagur PK, Cui K, Tunc I, Seifuddin F, Joshi AA, Stansky E, Purmalek MM, Rodante JA, Keel A, Aridi TZ, Carmona-Rivera C, Sanda GE, Chen MY, Pirooznia M, McCoy JP Jr, Gelfand JM, Zhao K, Gudjonsson JE, Playford MP, Kaplan MJ, Berger JS, Mehta NN. Teague HL, et al. Among authors: mehta nn. JACC Basic Transl Sci. 2019 Feb 25;4(1):1-14. doi: 10.1016/j.jacbts.2018.10.008. eCollection 2019 Feb. JACC Basic Transl Sci. 2019. PMID: 30847414 Free PMC article.
Joint AAD-NPF guidelines of care for the management and treatment of psoriasis with biologics.
Menter A, Strober BE, Kaplan DH, Kivelevitch D, Prater EF, Stoff B, Armstrong AW, Connor C, Cordoro KM, Davis DMR, Elewski BE, Gelfand JM, Gordon KB, Gottlieb AB, Kavanaugh A, Kiselica M, Korman NJ, Kroshinsky D, Lebwohl M, Leonardi CL, Lichten J, Lim HW, Mehta NN, Paller AS, Parra SL, Pathy AL, Rupani RN, Siegel M, Wong EB, Wu JJ, Hariharan V, Elmets CA. Menter A, et al. Among authors: mehta nn. J Am Acad Dermatol. 2019 Apr;80(4):1029-1072. doi: 10.1016/j.jaad.2018.11.057. Epub 2019 Feb 13. J Am Acad Dermatol. 2019. PMID: 30772098 Review.
Joint AAD-NPF guidelines of care for the management and treatment of psoriasis with awareness and attention to comorbidities.
Elmets CA, Leonardi CL, Davis DMR, Gelfand JM, Lichten J, Mehta NN, Armstrong AW, Connor C, Cordoro KM, Elewski BE, Gordon KB, Gottlieb AB, Kaplan DH, Kavanaugh A, Kivelevitch D, Kiselica M, Korman NJ, Kroshinsky D, Lebwohl M, Lim HW, Paller AS, Parra SL, Pathy AL, Prater EF, Rupani R, Siegel M, Stoff B, Strober BE, Wong EB, Wu JJ, Hariharan V, Menter A. Elmets CA, et al. Among authors: mehta nn. J Am Acad Dermatol. 2019 Apr;80(4):1073-1113. doi: 10.1016/j.jaad.2018.11.058. Epub 2019 Feb 13. J Am Acad Dermatol. 2019. PMID: 30772097 Review.
Coronary artery plaque characteristics and treatment with biologic therapy in severe psoriasis: results from a prospective observational study.
Elnabawi YA, Dey AK, Goyal A, Groenendyk JW, Chung JH, Belur AD, Rodante J, Harrington CL, Teague HL, Baumer Y, Keel A, Playford MP, Sandfort V, Chen MY, Lockshin B, Gelfand JM, Bluemke DA, Mehta NN. Elnabawi YA, et al. Among authors: mehta nn. Cardiovasc Res. 2019 Mar 15;115(4):721-728. doi: 10.1093/cvr/cvz009. Cardiovasc Res. 2019. PMID: 30721933 Free PMC article.
Prevalence of clinically significant incidental findings by whole-body fludeoxyglucose F 18 positron emission tomography/computed tomography scanning in moderate-to-severe psoriasis patients participating in clinical trials.
Wan MT, Torigian DA, Alavi A, Alvarez J, Chiesa Fuxench ZC, Noe MH, Papadopoulos M, Shin DB, Takeshita J, Werner TJ, Mehta NN, Gelfand JM. Wan MT, et al. Among authors: mehta nn. J Am Acad Dermatol. 2019 Jun;80(6):1630-1639. doi: 10.1016/j.jaad.2019.01.008. Epub 2019 Jan 14. J Am Acad Dermatol. 2019. PMID: 30654078 Free PMC article.
Association Between Oxidation-Modified Lipoproteins and Coronary Plaque in Psoriasis.
Sorokin AV, Kotani K, Elnabawi YA, Dey AK, Sajja AP, Yamada S, Ueda M, Harrington CL, Baumer Y, Rodante JA, Gelfand JM, Chen MY, Joshi AA, Playford MP, Remaley AT, Mehta NN. Sorokin AV, et al. Among authors: mehta nn. Circ Res. 2018 Nov 9;123(11):1244-1254. doi: 10.1161/CIRCRESAHA.118.313608. Circ Res. 2018. PMID: 30571459 Free PMC article.
Impact of Secukinumab on Endothelial Dysfunction and Other Cardiovascular Disease Parameters in Psoriasis Patients over 52 Weeks.
von Stebut E, Reich K, Thaçi D, Koenig W, Pinter A, Körber A, Rassaf T, Waisman A, Mani V, Yates D, Frueh J, Sieder C, Melzer N, Mehta NN, Gori T. von Stebut E, et al. Among authors: mehta nn. J Invest Dermatol. 2019 May;139(5):1054-1062. doi: 10.1016/j.jid.2018.10.042. Epub 2018 Nov 30. J Invest Dermatol. 2019. PMID: 30508547 Free article. Clinical Trial.
Chronic Stress-Related Neural Activity Associates With Subclinical Cardiovascular Disease in Psoriasis: A Prospective Cohort Study.
Goyal A, Dey AK, Chaturvedi A, Elnabawi YA, Aberra TM, Chung JH, Belur AD, Groenendyk JW, Lerman JB, Rivers JP, Rodante JA, Harrington CL, Varghese NJ, Sanda GE, Baumer Y, Sorokin AV, Teague HL, Genovese LD, Natarajan B, Joshi AA, Playford MP, Bluemke DA, Chen MY, Alavi A, Pitman RK, Powell-Wiley TM, Tawakol A, Gelfand JM, Mehta NN. Goyal A, et al. Among authors: mehta nn. JACC Cardiovasc Imaging. 2020 Feb;13(2 Pt 1):465-477. doi: 10.1016/j.jcmg.2018.08.038. Epub 2018 Nov 15. JACC Cardiovasc Imaging. 2020. PMID: 30448131 Free PMC article.
High density lipoprotein proteome is associated with cardiovascular risk factors and atherosclerosis burden as evaluated by coronary CT angiography.
Gordon SM, Chung JH, Playford MP, Dey AK, Sviridov D, Seifuddin F, Chen YC, Pirooznia M, Chen MY, Mehta NN, Remaley AT. Gordon SM, et al. Among authors: mehta nn. Atherosclerosis. 2018 Nov;278:278-285. doi: 10.1016/j.atherosclerosis.2018.09.032. Epub 2018 Sep 25. Atherosclerosis. 2018. PMID: 30347343 Free PMC article.
The protein acetylase GCN5L1 modulates hepatic fatty acid oxidation activity via acetylation of the mitochondrial β-oxidation enzyme HADHA.
Thapa D, Wu K, Stoner MW, Xie B, Zhang M, Manning JR, Lu Z, Li JH, Chen Y, Gucek M, Playford MP, Mehta NN, Harmon D, O'Doherty RM, Jurczak MJ, Sack MN, Scott I. Thapa D, et al. Among authors: mehta nn. J Biol Chem. 2018 Nov 16;293(46):17676-17684. doi: 10.1074/jbc.AC118.005462. Epub 2018 Oct 15. J Biol Chem. 2018. PMID: 30323061 Free PMC article.
Global and regional brain hypometabolism on FDG-PET in treated HIV-infected individuals.
Hammoud DA, Sinharay S, Steinbach S, Wakim PG, Geannopoulos K, Traino K, Dey AK, Tramont E, Rapoport SI, Snow J, Mehta NN, Smith BR, Nath A. Hammoud DA, et al. Among authors: mehta nn. Neurology. 2018 Oct 23;91(17):e1591-e1601. doi: 10.1212/WNL.0000000000006398. Epub 2018 Sep 26. Neurology. 2018. PMID: 30258017 Free PMC article.
Association Between Aortic Vascular Inflammation and Coronary Artery Plaque Characteristics in Psoriasis.
Joshi AA, Lerman JB, Dey AK, Sajja AP, Belur AD, Elnabawi YA, Rodante JA, Aberra TM, Chung J, Salahuddin T, Natarajan B, Dave J, Goyal A, Groenendyk JW, Rivers JP, Baumer Y, Teague HL, Playford MP, Bluemke DA, Ahlman MA, Chen MY, Gelfand JM, Mehta NN. Joshi AA, et al. Among authors: mehta nn. JAMA Cardiol. 2018 Oct 1;3(10):949-956. doi: 10.1001/jamacardio.2018.2769. JAMA Cardiol. 2018. PMID: 30208407 Free PMC article.
Effect of 2 Psoriasis Treatments on Vascular Inflammation and Novel Inflammatory Cardiovascular Biomarkers: A Randomized Placebo-Controlled Trial.
Mehta NN, Shin DB, Joshi AA, Dey AK, Armstrong AW, Duffin KC, Fuxench ZC, Harrington CL, Hubbard RA, Kalb RE, Menter A, Rader DJ, Reilly MP, Simpson EL, Takeshita J, Torigian DA, Werner TJ, Troxel AB, Tyring SK, Vanderbeek SB, Van Voorhees AS, Playford MP, Ahlman MA, Alavi A, Gelfand JM. Mehta NN, et al. Circ Cardiovasc Imaging. 2018 Jun;11(6):e007394. doi: 10.1161/CIRCIMAGING.117.007394. Circ Cardiovasc Imaging. 2018. PMID: 29776990 Free PMC article. Clinical Trial.
Identification of proresolving and inflammatory lipid mediators in human psoriasis.
Sorokin AV, Norris PC, English JT, Dey AK, Chaturvedi A, Baumer Y, Silverman J, Playford MP, Serhan CN, Mehta NN. Sorokin AV, et al. Among authors: mehta nn. J Clin Lipidol. 2018 Jul-Aug;12(4):1047-1060. doi: 10.1016/j.jacl.2018.03.091. Epub 2018 Apr 6. J Clin Lipidol. 2018. PMID: 29730187 Free PMC article.
Neutrophil subsets and their gene signature associate with vascular inflammation and coronary atherosclerosis in lupus.
Carlucci PM, Purmalek MM, Dey AK, Temesgen-Oyelakin Y, Sakhardande S, Joshi AA, Lerman JB, Fike A, Davis M, Chung JH, Playford MP, Naqi M, Mistry P, Gutierrez-Cruz G, Dell'Orso S, Naz F, Salahuddin T, Natarajan B, Manna Z, Tsai WL, Gupta S, Grayson P, Teague H, Chen MY, Sun HW, Hasni S, Mehta NN, Kaplan MJ. Carlucci PM, et al. Among authors: mehta nn. JCI Insight. 2018 Apr 19;3(8):e99276. doi: 10.1172/jci.insight.99276. eCollection 2018 Apr 19. JCI Insight. 2018. PMID: 29669944 Free PMC article. Clinical Trial.
Bioactive Lipid Mediator Profiles in Human Psoriasis Skin and Blood.
Sorokin AV, Domenichiello AF, Dey AK, Yuan ZX, Goyal A, Rose SM, Playford MP, Ramsden CE, Mehta NN. Sorokin AV, et al. Among authors: mehta nn. J Invest Dermatol. 2018 Jul;138(7):1518-1528. doi: 10.1016/j.jid.2018.02.003. Epub 2018 Feb 15. J Invest Dermatol. 2018. PMID: 29454560 Free PMC article.
Chronic skin inflammation accelerates macrophage cholesterol crystal formation and atherosclerosis.
Baumer Y, Ng Q, Sanda GE, Dey AK, Teague HL, Sorokin AV, Dagur PK, Silverman JI, Harrington CL, Rodante JA, Rose SM, Varghese NJ, Belur AD, Goyal A, Gelfand JM, Springer DA, Bleck CK, Thomas CL, Yu ZX, Winge MC, Kruth HS, Marinkovich MP, Joshi AA, Playford MP, Mehta NN. Baumer Y, et al. Among authors: mehta nn. JCI Insight. 2018 Jan 11;3(1):e97179. doi: 10.1172/jci.insight.97179. eCollection 2018 Jan 11. JCI Insight. 2018. PMID: 29321372 Free PMC article.
Internal tissue references for 18Fluorodeoxyglucose vascular inflammation imaging: Implications for cardiovascular risk stratification and clinical trials.
Ahlman MA, Vigneault DM, Sandfort V, Maass-Moreno R, Dave J, Sadek A, Mallek MB, Selwaness MAF, Herscovitch P, Mehta NN, Bluemke DA. Ahlman MA, et al. Among authors: mehta nn. PLoS One. 2017 Nov 13;12(11):e0187995. doi: 10.1371/journal.pone.0187995. eCollection 2017. PLoS One. 2017. PMID: 29131857 Free PMC article.
Prospective Analysis of Lipid Composition Changes with Antiretroviral Therapy and Immune Activation in Persons Living with HIV.
Belury MA, Bowman E, Gabriel J, Snyder B, Kulkarni M, Palettas M, Mo X, Lake JE, Zidar D, Sieg SF, Rodriguez B, Playford MP, Andrade A, Kuritzkes DR, Mehta NN, Lederman MM, Funderburg NT. Belury MA, et al. Among authors: mehta nn. Pathog Immun. 2017;2(3):376-403. doi: 10.20411/pai.v2i3.218. Epub 2017 Oct 6. Pathog Immun. 2017. PMID: 29098203 Free PMC article.
IFN-γ and TNF-α synergism may provide a link between psoriasis and inflammatory atherogenesis.
Mehta NN, Teague HL, Swindell WR, Baumer Y, Ward NL, Xing X, Baugous B, Johnston A, Joshi AA, Silverman J, Barnes DH, Wolterink L, Nair RP, Stuart PE, Playford M, Voorhees JJ, Sarkar MK, Elder JT, Gallagher K, Ganesh SK, Gudjonsson JE. Mehta NN, et al. Sci Rep. 2017 Oct 23;7(1):13831. doi: 10.1038/s41598-017-14365-1. Sci Rep. 2017. PMID: 29062018 Free PMC article.
Visceral Adiposity in Psoriasis is Associated With Vascular Inflammation by 18F-Fluorodeoxyglucose Positron-Emission Tomography/Computed Tomography Beyond Cardiometabolic Disease Risk Factors in an Observational Cohort Study.
Rivers JP, Powell-Wiley TM, Dey AK, Rodante JA, Chung JH, Joshi AA, Natarajan B, Sajja AP, Chaturvedi A, Rana A, Harrington CL, Teague HL, Lockshin BN, Ahlman MA, Yao J, Playford MP, Gelfand JM, Mehta NN. Rivers JP, et al. Among authors: mehta nn. JACC Cardiovasc Imaging. 2018 Feb;11(2 Pt 2):349-357. doi: 10.1016/j.jcmg.2017.08.014. Epub 2017 Oct 18. JACC Cardiovasc Imaging. 2018. PMID: 29055628 Free PMC article.
Unraveling Vascular Inflammation: From Immunology to Imaging.
Teague HL, Ahlman MA, Alavi A, Wagner DD, Lichtman AH, Nahrendorf M, Swirski FK, Nestle F, Gelfand JM, Kaplan MJ, Grinspoon S, Ridker PM, Newby DE, Tawakol A, Fayad ZA, Mehta NN. Teague HL, et al. Among authors: mehta nn. J Am Coll Cardiol. 2017 Sep 12;70(11):1403-1412. doi: 10.1016/j.jacc.2017.07.750. J Am Coll Cardiol. 2017. PMID: 28882238 Free PMC article. Review.
A systems approach for discovering linoleic acid derivatives that potentially mediate pain and itch.
Ramsden CE, Domenichiello AF, Yuan ZX, Sapio MR, Keyes GS, Mishra SK, Gross JR, Majchrzak-Hong S, Zamora D, Horowitz MS, Davis JM, Sorokin AV, Dey A, LaPaglia DM, Wheeler JJ, Vasko MR, Mehta NN, Mannes AJ, Iadarola MJ. Ramsden CE, et al. Among authors: mehta nn. Sci Signal. 2017 Aug 22;10(493):eaal5241. doi: 10.1126/scisignal.aal5241. Sci Signal. 2017. PMID: 28831021 Free PMC article.
Peer Review Practices for Evaluating Biomedical Research Grants: A Scientific Statement From the American Heart Association.
Liaw L, Freedman JE, Becker LB, Mehta NN, Liscum L; Peer Review Subcommittee of the American Heart Association National Research Committee; Council on Cardiovascular and Stroke Nursing; Council on Cardiovascular Radiology and Intervention; Council on Cardiovascular Surgery and Anesthesia; Council on Clinical Cardiology; Council on Functional Genomics and Translational Biology; Council on Hypertension; Council on Quality of Care and Outcomes Research; and Stroke Council. Liaw L, et al. Among authors: mehta nn. Circ Res. 2017 Aug 4;121(4):e9-e19. doi: 10.1161/RES.0000000000000158. Epub 2017 Jul 6. Circ Res. 2017. PMID: 28684631 Review.
Association Between Skin and Aortic Vascular Inflammation in Patients With Psoriasis: A Case-Cohort Study Using Positron Emission Tomography/Computed Tomography.
Dey AK, Joshi AA, Chaturvedi A, Lerman JB, Aberra TM, Rodante JA, Teague HL, Harrington CL, Rivers JP, Chung JH, Kabbany MT, Natarajan B, Silverman JI, Ng Q, Sanda GE, Sorokin AV, Baumer Y, Gerson E, Prussick RB, Ehrlich A, Green LJ, Lockshin BN, Ahlman MA, Playford MP, Gelfand JM, Mehta NN. Dey AK, et al. Among authors: mehta nn. JAMA Cardiol. 2017 Sep 1;2(9):1013-1018. doi: 10.1001/jamacardio.2017.1213. JAMA Cardiol. 2017. PMID: 28564678 Free PMC article.
Pediatric Psoriasis Comorbidity Screening Guidelines.
Osier E, Wang AS, Tollefson MM, Cordoro KM, Daniels SR, Eichenfield A, Gelfand JM, Gottlieb AB, Kimball AB, Lebwohl M, Mehta NN, Paller AS, Schwimmer JB, Styne DM, Van Voorhees AS, Tom WL, Eichenfield LF. Osier E, et al. Among authors: mehta nn. JAMA Dermatol. 2017 Jul 1;153(7):698-704. doi: 10.1001/jamadermatol.2017.0499. JAMA Dermatol. 2017. PMID: 28514463 Free PMC article.
Coronary Plaque Characterization in Psoriasis Reveals High-Risk Features That Improve After Treatment in a Prospective Observational Study.
Lerman JB, Joshi AA, Chaturvedi A, Aberra TM, Dey AK, Rodante JA, Salahuddin T, Chung JH, Rana A, Teague HL, Wu JJ, Playford MP, Lockshin BA, Chen MY, Sandfort V, Bluemke DA, Mehta NN. Lerman JB, et al. Among authors: mehta nn. Circulation. 2017 Jul 18;136(3):263-276. doi: 10.1161/CIRCULATIONAHA.116.026859. Epub 2017 May 8. Circulation. 2017. PMID: 28483812 Free PMC article.
Psoriasis as a human model of disease to study inflammatory atherogenesis.
Harrington CL, Dey AK, Yunus R, Joshi AA, Mehta NN. Harrington CL, et al. Among authors: mehta nn. Am J Physiol Heart Circ Physiol. 2017 May 1;312(5):H867-H873. doi: 10.1152/ajpheart.00774.2016. Epub 2017 Mar 3. Am J Physiol Heart Circ Physiol. 2017. PMID: 28258057 Free PMC article. Review.
Psoriasis and comorbid diseases: Implications for management.
Takeshita J, Grewal S, Langan SM, Mehta NN, Ogdie A, Van Voorhees AS, Gelfand JM. Takeshita J, et al. Among authors: mehta nn. J Am Acad Dermatol. 2017 Mar;76(3):393-403. doi: 10.1016/j.jaad.2016.07.065. J Am Acad Dermatol. 2017. PMID: 28212760 Free PMC article. Review.
Psoriasis and comorbid diseases: Epidemiology.
Takeshita J, Grewal S, Langan SM, Mehta NN, Ogdie A, Van Voorhees AS, Gelfand JM. Takeshita J, et al. Among authors: mehta nn. J Am Acad Dermatol. 2017 Mar;76(3):377-390. doi: 10.1016/j.jaad.2016.07.064. J Am Acad Dermatol. 2017. PMID: 28212759 Free PMC article. Review.
Psoriasis.
Greb JE, Goldminz AM, Elder JT, Lebwohl MG, Gladman DD, Wu JJ, Mehta NN, Finlay AY, Gottlieb AB. Greb JE, et al. Among authors: mehta nn. Nat Rev Dis Primers. 2016 Nov 24;2:16082. doi: 10.1038/nrdp.2016.82. Nat Rev Dis Primers. 2016. PMID: 27883001 Review.
GlycA Is a Novel Biomarker of Inflammation and Subclinical Cardiovascular Disease in Psoriasis.
Joshi AA, Lerman JB, Aberra TM, Afshar M, Teague HL, Rodante JA, Krishnamoorthy P, Ng Q, Aridi TZ, Salahuddin T, Natarajan B, Lockshin BN, Ahlman MA, Chen MY, Rader DJ, Reilly MP, Remaley AT, Bluemke DA, Playford MP, Gelfand JM, Mehta NN. Joshi AA, et al. Among authors: mehta nn. Circ Res. 2016 Nov 11;119(11):1242-1253. doi: 10.1161/CIRCRESAHA.116.309637. Epub 2016 Sep 21. Circ Res. 2016. PMID: 27654120 Free PMC article.
Lupus high-density lipoprotein induces proinflammatory responses in macrophages by binding lectin-like oxidised low-density lipoprotein receptor 1 and failing to promote activating transcription factor 3 activity.
Smith CK, Seto NL, Vivekanandan-Giri A, Yuan W, Playford MP, Manna Z, Hasni SA, Kuai R, Mehta NN, Schwendeman A, Pennathur S, Kaplan MJ. Smith CK, et al. Among authors: mehta nn. Ann Rheum Dis. 2017 Mar;76(3):602-611. doi: 10.1136/annrheumdis-2016-209683. Epub 2016 Aug 19. Ann Rheum Dis. 2017. PMID: 27543414 Free PMC article.
Self-reported depression in psoriasis is associated with subclinical vascular diseases.
Aberra TM, Joshi AA, Lerman JB, Rodante JA, Dahiya AK, Teague HL, Ng Q, Silverman JI, Sorokin AV, Salahuddin T, Lockshin BN, Ahlman MA, Playford MP, Chen MY, Gelfand JM, Mehta NN. Aberra TM, et al. Among authors: mehta nn. Atherosclerosis. 2016 Aug;251:219-225. doi: 10.1016/j.atherosclerosis.2016.05.043. Epub 2016 May 27. Atherosclerosis. 2016. PMID: 27376696 Free PMC article.
National Heart, Lung, and Blood Institute Working Group Report on Salt in Human Health and Sickness: Building on the Current Scientific Evidence.
Oh YS, Appel LJ, Galis ZS, Hafler DA, He J, Hernandez AL, Joe B, Karumanchi SA, Maric-Bilkan C, Mattson D, Mehta NN, Randolph G, Ryan M, Sandberg K, Titze J, Tolunay E, Toney GM, Harrison DG. Oh YS, et al. Among authors: mehta nn. Hypertension. 2016 Aug;68(2):281-8. doi: 10.1161/HYPERTENSIONAHA.116.07415. Epub 2016 Jun 20. Hypertension. 2016. PMID: 27324228 Free PMC article. Review. No abstract available.
Lipid Abnormalities and Inflammation in HIV Inflection.
Funderburg NT, Mehta NN. Funderburg NT, et al. Among authors: mehta nn. Curr HIV/AIDS Rep. 2016 Aug;13(4):218-25. doi: 10.1007/s11904-016-0321-0. Curr HIV/AIDS Rep. 2016. PMID: 27245605 Free PMC article. Review.
Severity of Psoriasis Associates With Aortic Vascular Inflammation Detected by FDG PET/CT and Neutrophil Activation in a Prospective Observational Study.
Naik HB, Natarajan B, Stansky E, Ahlman MA, Teague H, Salahuddin T, Ng Q, Joshi AA, Krishnamoorthy P, Dave J, Rose SM, Doveikis J, Playford MP, Prussick RB, Ehrlich A, Kaplan MJ, Lockshin BN, Gelfand JM, Mehta NN. Naik HB, et al. Among authors: mehta nn. Arterioscler Thromb Vasc Biol. 2015 Dec;35(12):2667-76. doi: 10.1161/ATVBAHA.115.306460. Epub 2015 Oct 8. Arterioscler Thromb Vasc Biol. 2015. PMID: 26449753 Free PMC article.
Psoriasis and Cardiovascular Risk: Strength in Numbers Part 3.
Ogdie A, Troxel AB, Mehta NN, Gelfand JM. Ogdie A, et al. Among authors: mehta nn. J Invest Dermatol. 2015 Sep;135(9):2148-2150. doi: 10.1038/jid.2015.218. J Invest Dermatol. 2015. PMID: 26269404 Free PMC article.
Serum Fractalkine (CX3CL1) and Cardiovascular Outcomes and Diabetes: Findings From the Chronic Renal Insufficiency Cohort (CRIC) Study.
Shah R, Matthews GJ, Shah RY, McLaughlin C, Chen J, Wolman M, Master SR, Chai B, Xie D, Rader DJ, Raj DS, Mehta NN, Budoff M, Fischer MJ, Go AS, Townsend RR, He J, Kusek JW, Feldman HI, Foulkes AS, Reilly MP; CRIC Study Investigators. Shah R, et al. Among authors: mehta nn. Am J Kidney Dis. 2015 Aug;66(2):266-73. doi: 10.1053/j.ajkd.2015.01.021. Epub 2015 Mar 17. Am J Kidney Dis. 2015. PMID: 25795074 Free PMC article.
A pilot trial to examine the effect of high-dose niacin on arterial wall inflammation using fluorodeoxyglucose positron emission tomography.
deGoma EM, Salavati A, Shinohara RT, Saboury B, Pollan L, Schoen M, Torigian DA, Mohler ER, Dunbar RL, Litt HI, Woo J, Rader DJ, Alavi A, Mehta NN. deGoma EM, et al. Among authors: mehta nn. Acad Radiol. 2015 May;22(5):600-9. doi: 10.1016/j.acra.2014.12.015. Epub 2015 Feb 21. Acad Radiol. 2015. PMID: 25708866 Clinical Trial.
Oxidized LDL Levels Are Increased in HIV Infection and May Drive Monocyte Activation.
Zidar DA, Juchnowski S, Ferrari B, Clagett B, Pilch-Cooper HA, Rose S, Rodriguez B, McComsey GA, Sieg SF, Mehta NN, Lederman MM, Funderburg NT. Zidar DA, et al. Among authors: mehta nn. J Acquir Immune Defic Syndr. 2015 Jun 1;69(2):154-60. doi: 10.1097/QAI.0000000000000566. J Acquir Immune Defic Syndr. 2015. PMID: 25647528 Free PMC article.
Lipoprotein concentration, particle number, size and cholesterol efflux capacity are associated with mitochondrial oxidative stress and function in an HIV positive cohort.
Parikh NI, Gerschenson M, Bennett K, Gangcuangco LM, Lopez MS, Mehta NN, Playford MP, Nakamoto BK, Seto TB, Chow DC, Shikuma CM. Parikh NI, et al. Among authors: mehta nn. Atherosclerosis. 2015 Mar;239(1):50-4. doi: 10.1016/j.atherosclerosis.2014.12.005. Epub 2014 Dec 20. Atherosclerosis. 2015. PMID: 25574857 Free PMC article.
Characterization of lipid composition and high-density lipoprotein function in HIV-infected individuals on stable antiretroviral regimens.
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Risk of major cardiovascular events in patients with psoriatic arthritis, psoriasis and rheumatoid arthritis: a population-based cohort study.
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