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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1945 1
1946 1
1950 2
1951 1
1955 2
1957 2
1959 1
1960 2
1962 1
1963 2
1964 2
1965 1
1967 1
1974 1
1975 1
1976 2
1977 2
1978 1
1979 7
1980 12
1981 12
1982 20
1983 29
1984 43
1985 27
1986 47
1987 41
1988 47
1989 71
1990 59
1991 71
1992 75
1993 95
1994 119
1995 110
1996 124
1997 117
1998 121
1999 115
2000 141
2001 150
2002 153
2003 162
2004 172
2005 181
2006 205
2007 212
2008 215
2009 254
2010 259
2011 340
2012 318
2013 379
2014 398
2015 395
2016 371
2017 350
2018 364
2019 346
2020 421
2021 350
2022 349
2023 307
2024 142

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7,402 results

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Page 1
The importance of the ratio of omega-6/omega-3 essential fatty acids.
Simopoulos AP. Simopoulos AP. Biomed Pharmacother. 2002 Oct;56(8):365-79. doi: 10.1016/s0753-3322(02)00253-6. Biomed Pharmacother. 2002. PMID: 12442909 Review.
Western diets are deficient in omega-3 fatty acids, and have excessive amounts of omega-6 fatty acids compared with the diet on which human beings evolved and their genetic patterns were established. ...A lower ratio of o …
Western diets are deficient in omega-3 fatty acids, and have excessive amounts of omega-6 fatty …
Beneficial Outcomes of Omega-6 and Omega-3 Polyunsaturated Fatty Acids on Human Health: An Update for 2021.
Djuricic I, Calder PC. Djuricic I, et al. Nutrients. 2021 Jul 15;13(7):2421. doi: 10.3390/nu13072421. Nutrients. 2021. PMID: 34371930 Free PMC article. Review.
Oxidative stress and inflammation have been recognized as important contributors to the risk of chronic non-communicable diseases. Polyunsaturated fatty acids (PUFAs) may regulate the antioxidant signaling pathway and modulate inflammatory processes. ...In addition …
Oxidative stress and inflammation have been recognized as important contributors to the risk of chronic non-communicable diseases. Polyunsat …
Omega-6 fatty acids and inflammation.
Innes JK, Calder PC. Innes JK, et al. Prostaglandins Leukot Essent Fatty Acids. 2018 May;132:41-48. doi: 10.1016/j.plefa.2018.03.004. Epub 2018 Mar 22. Prostaglandins Leukot Essent Fatty Acids. 2018. PMID: 29610056 Review.
Hence, it is commonly believed that increasing dietary intake of the omega-6 fatty acids ARA or its precursor linoleic acid (LA) will increase inflammation. ...Thus, the interaction of omega-3 and omega-6 fatty aci …
Hence, it is commonly believed that increasing dietary intake of the omega-6 fatty acids ARA or its precursor li …
Omega-3 and omega-6 polyunsaturated fatty acids: Dietary sources, metabolism, and significance - A review.
Saini RK, Keum YS. Saini RK, et al. Life Sci. 2018 Jun 15;203:255-267. doi: 10.1016/j.lfs.2018.04.049. Epub 2018 Apr 30. Life Sci. 2018. PMID: 29715470 Review.
Linoleic acid (LA) (n-6) and alpha-linolenic acid (ALA) (n-3) are essential fatty acids (EFAs) as they cannot be synthesized by humans or other higher animals. In the human body, these fatty acids (FAs) give rise to arachidonic acid (ARA, n-6), eicosap …
Linoleic acid (LA) (n-6) and alpha-linolenic acid (ALA) (n-3) are essential fatty acids (EFAs) as they cannot be synthesized b …
Omega-3 Versus Omega-6 Polyunsaturated Fatty Acids in the Prevention and Treatment of Inflammatory Skin Diseases.
Balić A, Vlašić D, Žužul K, Marinović B, Bukvić Mokos Z. Balić A, et al. Int J Mol Sci. 2020 Jan 23;21(3):741. doi: 10.3390/ijms21030741. Int J Mol Sci. 2020. PMID: 31979308 Free PMC article. Review.
Omega-3 (omega-3) and omega-6 (omega-6) polyunsaturated fatty acids (PUFAs) are nowadays desirable components of oils with special dietary and functional properties. ...It seems that combined omega-6 …
Omega-3 (omega-3) and omega-6 (omega-6) polyunsaturated fatty acids (P …
Omega-3 Fatty Acids for the Management of Osteoarthritis: A Narrative Review.
Cordingley DM, Cornish SM. Cordingley DM, et al. Nutrients. 2022 Aug 16;14(16):3362. doi: 10.3390/nu14163362. Nutrients. 2022. PMID: 36014868 Free PMC article. Review.
OA is characterized by a state of low-grade inflammation which leads to a greater state of cellular catabolism disrupting the homeostasis of cartilage synthesis and degradation. Omega-3 polyunsaturated fatty acids (PUFAs) have been postulated as a pote …
OA is characterized by a state of low-grade inflammation which leads to a greater state of cellular catabolism disrupting the homeostasis of …
Omega-3 fatty acids for breast cancer prevention and survivorship.
Fabian CJ, Kimler BF, Hursting SD. Fabian CJ, et al. Breast Cancer Res. 2015 May 4;17(1):62. doi: 10.1186/s13058-015-0571-6. Breast Cancer Res. 2015. PMID: 25936773 Free PMC article. Review.
Women with evidence of high intake ratios of the marine omega-3 fatty acids eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) relative to the omega-6 arachidonic acid have been found to have a reduced risk of breast cancer compar …
Women with evidence of high intake ratios of the marine omega-3 fatty acids eicosapentaenoic acid (EPA) and doco …
Peroxidation of n-3 and n-6 polyunsaturated fatty acids in the acidic tumor environment leads to ferroptosis-mediated anticancer effects.
Dierge E, Debock E, Guilbaud C, Corbet C, Mignolet E, Mignard L, Bastien E, Dessy C, Larondelle Y, Feron O. Dierge E, et al. Cell Metab. 2021 Aug 3;33(8):1701-1715.e5. doi: 10.1016/j.cmet.2021.05.016. Epub 2021 Jun 11. Cell Metab. 2021. PMID: 34118189 Free article.
Tumor acidosis promotes disease progression through a stimulation of fatty acid (FA) metabolism in cancer cells. Instead of blocking the use of FAs by acidic cancer cells, we examined whether excess uptake of specific FAs could lead to antitumor effects. ...
Tumor acidosis promotes disease progression through a stimulation of fatty acid (FA) metabolism in cancer cells. Instead of blocking …
An Increase in the Omega-6/Omega-3 Fatty Acid Ratio Increases the Risk for Obesity.
Simopoulos AP. Simopoulos AP. Nutrients. 2016 Mar 2;8(3):128. doi: 10.3390/nu8030128. Nutrients. 2016. PMID: 26950145 Free PMC article. Review.
Experimental studies have suggested that omega-6 and omega-3 fatty acids elicit divergent effects on body fat gain through mechanisms of adipogenesis, browning of adipose tissue, lipid homeostasis, brain-gut-adipose tissue axis, and most …
Experimental studies have suggested that omega-6 and omega-3 fatty acids elicit divergent effects …
Effects of Dietary n-3 and n-6 Polyunsaturated Fatty Acids in Inflammation and Cancerogenesis.
Liput KP, Lepczyński A, Ogłuszka M, Nawrocka A, Poławska E, Grzesiak A, Ślaska B, Pareek CS, Czarnik U, Pierzchała M. Liput KP, et al. Int J Mol Sci. 2021 Jun 28;22(13):6965. doi: 10.3390/ijms22136965. Int J Mol Sci. 2021. PMID: 34203461 Free PMC article. Review.
The dietary recommendation encourages reducing saturated fatty acids (SFA) in diet and replacing them with polyunsaturated fatty acids (PUFAs) n-3 (omega-3) and n-6 (omega-6) to decrease the risk of metabolic disturbances. . …
The dietary recommendation encourages reducing saturated fatty acids (SFA) in diet and replacing them with polyunsaturated …
7,402 results