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S-phenylpiracetam, a selective DAT inhibitor, reduces body weight gain without influencing locomotor activity.
Zvejniece L, Svalbe B, Vavers E, Makrecka-Kuka M, Makarova E, Liepins V, Kalvinsh I, Liepinsh E, Dambrova M. Zvejniece L, et al. Pharmacol Biochem Behav. 2017 Sep;160:21-29. doi: 10.1016/j.pbb.2017.07.009. Epub 2017 Jul 22. Pharmacol Biochem Behav. 2017. PMID: 28743458
S-phenylpiracetam is an optical isomer of phenotropil, which is a clinically used nootropic drug that improves physical condition and cognition. ...S-phenylpiracetam did not influence locomotor activity in the obese Zucker rats or in the WD-fed mice. ...
S-phenylpiracetam is an optical isomer of phenotropil, which is a clinically used nootropic drug that improves physical condition and …
Asymmetric Michael Addition in Synthesis of β-Substituted GABA Derivatives.
Han J, Escorihuela J, Fustero S, Landa A, Soloshonok VA, Sorochinsky A. Han J, et al. Molecules. 2022 Jun 13;27(12):3797. doi: 10.3390/molecules27123797. Molecules. 2022. PMID: 35744921 Free PMC article. Review.
For example, beta-substituted GABA derivatives are found in numerous neurological drugs, such as baclofen, phenibut, tolibut, pregabalin, phenylpiracetam, brivaracetam, and rolipram, to mention just a few. In this review, we critically discuss the literature data reported …
For example, beta-substituted GABA derivatives are found in numerous neurological drugs, such as baclofen, phenibut, tolibut, pregabalin, …
Neuroprotective and anti-inflammatory activity of DAT inhibitor R-phenylpiracetam in experimental models of inflammation in male mice.
Zvejniece L, Zvejniece B, Videja M, Stelfa G, Vavers E, Grinberga S, Svalbe B, Dambrova M. Zvejniece L, et al. Inflammopharmacology. 2020 Oct;28(5):1283-1292. doi: 10.1007/s10787-020-00705-7. Epub 2020 Apr 11. Inflammopharmacology. 2020. PMID: 32279140
R-phenylpiracetam (R-PhP, (4R)-2-(4-phenyl-2-oxopyrrolidin-1-yl)acetamide) is an optical isomer of phenotropil, a clinically-used nootropic drug that improves physical condition and cognition. ...
R-phenylpiracetam (R-PhP, (4R)-2-(4-phenyl-2-oxopyrrolidin-1-yl)acetamide) is an optical isomer of phenotropil, a clinically-used noo …
Unauthorized ingredients in "nootropic" dietary supplements: A review of the history, pharmacology, prevalence, international regulations, and potential as doping agents.
Jędrejko K, Catlin O, Stewart T, Anderson A, Muszyńska B, Catlin DH. Jędrejko K, et al. Drug Test Anal. 2023 Aug;15(8):803-839. doi: 10.1002/dta.3529. Epub 2023 Jun 25. Drug Test Anal. 2023. PMID: 37357012 Review.
The first nootropic prohibited in sport was fonturacetam (4-phenylpiracetam, carphedon) in 1998. Presented here 25 years later is a broad-scale consideration of the history, pharmacology, prevalence, regulations, and doping potential of nootropics viewed through a lens of …
The first nootropic prohibited in sport was fonturacetam (4-phenylpiracetam, carphedon) in 1998. Presented here 25 years later is a b …
Piracetam and piracetam-like drugs: from basic science to novel clinical applications to CNS disorders.
Malykh AG, Sadaie MR. Malykh AG, et al. Drugs. 2010 Feb 12;70(3):287-312. doi: 10.2165/11319230-000000000-00000. Drugs. 2010. PMID: 20166767 Review.
Subgroup 1 drugs include piracetam, oxiracetam, aniracetam, pramiracetam and phenylpiracetam, which have been used in humans and some of which are available as dietary supplements. ...As add-on therapy, it appears to benefit individuals with myoclonus epilepsy and tardive …
Subgroup 1 drugs include piracetam, oxiracetam, aniracetam, pramiracetam and phenylpiracetam, which have been used in humans and some …
Five Unapproved Drugs Found in Cognitive Enhancement Supplements.
Cohen PA, Avula B, Wang YH, Zakharevich I, Khan I. Cohen PA, et al. Neurol Clin Pract. 2021 Jun;11(3):e303-e307. doi: 10.1212/CPJ.0000000000000960. Neurol Clin Pract. 2021. PMID: 34484905 Free PMC article.
METHODS: Supplements were identified by searching 2 supplement databases for products labeled as containing omberacetam, aniracetam, phenylpiracetam, or oxiracetam, 4 drugs not approved for human use in the United States. ...
METHODS: Supplements were identified by searching 2 supplement databases for products labeled as containing omberacetam, aniracetam, phen …
[Molecularly imprinted sorbent for biological fluids sample preparation in forensic toxicology].
Voronin AV, Malkova TL, Synbulatov IV. Voronin AV, et al. Sud Med Ekspert. 2021;64(6):39-42. doi: 10.17116/sudmed20216406139. Sud Med Ekspert. 2021. PMID: 34814644 Russian.
The phenylpiracetam recovery from blood and urine model samples is 75% for concentration range of 100.0-6000.0 ng/ml. The accuracy of phenylpiracetam extraction does not exceed 12% for blood samples and 6% for urine samples. ...
The phenylpiracetam recovery from blood and urine model samples is 75% for concentration range of 100.0-6000.0 ng/ml. The accuracy of …
A study of the mechanisms for antiaggregant activity of pyrrolidone derivatives in rats with chronic hyperglycemia.
Zhilyuk VI, Levykh AE, Mamchur VI. Zhilyuk VI, et al. Bull Exp Biol Med. 2014 Apr;156(6):799-802. doi: 10.1007/s10517-014-2454-8. Epub 2014 May 3. Bull Exp Biol Med. 2014. PMID: 24824701
In rats with chronic alloxan-induced hyperglycemia, pramiracetam and phenylpiracetam (but not piracetam) had a strong antiaggregant effect that was mediated by various mechanisms of platelet aggregation modulation. The effect of pramiracetam is mainly realized via the inhi …
In rats with chronic alloxan-induced hyperglycemia, pramiracetam and phenylpiracetam (but not piracetam) had a strong antiaggregant e …
[Role of functional state of neuronal mitochondria of cerebral cortex in mechanisms of nootropic activity of neuroprotectors in rats with alloxan hyperglycemia].
Zhiliuk VI, Mamchur VI, Pavlov SV. Zhiliuk VI, et al. Eksp Klin Farmakol. 2015;78(2):10-4. Eksp Klin Farmakol. 2015. PMID: 25898541 Russian.
The influence of citicoline, phenylpiracetam, pentoxifylline and N-phenylacetyl-L-prolylglycine on cognitive processes and functional state of mitochondria in the neocortex of alloxan-diabetic rats has been studied. ...Functional status of mitochondria was assessed by mito …
The influence of citicoline, phenylpiracetam, pentoxifylline and N-phenylacetyl-L-prolylglycine on cognitive processes and functional …
27 results