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Progressive methylation of ageing histones by Dot1 functions as a timer.
De Vos D, Frederiks F, Terweij M, van Welsem T, Verzijlbergen KF, Iachina E, de Graaf EL, Altelaar AF, Oudgenoeg G, Heck AJ, Krijgsveld J, Bakker BM, van Leeuwen F. De Vos D, et al. Among authors: van leeuwen f, van welsem t. EMBO Rep. 2011 Sep 1;12(9):956-62. doi: 10.1038/embor.2011.131. EMBO Rep. 2011. PMID: 21760613 Free PMC article.
Flexibility in crosstalk between H2B ubiquitination and H3 methylation in vivo.
Vlaming H, van Welsem T, de Graaf EL, Ontoso D, Altelaar AF, San-Segundo PA, Heck AJ, van Leeuwen F. Vlaming H, et al. Among authors: van leeuwen f, van welsem t. EMBO Rep. 2014 Oct;15(10):1077-84. doi: 10.15252/embr.201438793. Epub 2014 Aug 20. EMBO Rep. 2014. PMID: 25141862 Free PMC article.
Conserved crosstalk between histone deacetylation and H3K79 methylation generates DOT1L-dose dependency in HDAC1-deficient thymic lymphoma.
Vlaming H, McLean CM, Korthout T, Alemdehy MF, Hendriks S, Lancini C, Palit S, Klarenbeek S, Kwesi-Maliepaard EM, Molenaar TM, Hoekman L, Schmidlin TT, Altelaar AM, van Welsem T, Dannenberg JH, Jacobs H, van Leeuwen F. Vlaming H, et al. Among authors: van leeuwen f, van welsem t. EMBO J. 2019 Jul 15;38(14):e101564. doi: 10.15252/embj.2019101564. Epub 2019 Jun 17. EMBO J. 2019. PMID: 31304633 Free PMC article.
Yeast PP4 interacts with ATR homolog Ddc2-Mec1 and regulates checkpoint signaling.
Hustedt N, Seeber A, Sack R, Tsai-Pflugfelder M, Bhullar B, Vlaming H, van Leeuwen F, Guénolé A, van Attikum H, Srivas R, Ideker T, Shimada K, Gasser SM. Hustedt N, et al. Among authors: van leeuwen f, van attikum h. Mol Cell. 2015 Jan 22;57(2):273-89. doi: 10.1016/j.molcel.2014.11.016. Epub 2014 Dec 18. Mol Cell. 2015. PMID: 25533186 Free PMC article.
Histone methyltransferase DOT1L controls state-specific identity during B cell differentiation.
Aslam MA, Alemdehy MF, Kwesi-Maliepaard EM, Muhaimin FI, Caganova M, Pardieck IN, van den Brand T, van Welsem T, de Rink I, Song JY, de Wit E, Arens R, Jacobs H, van Leeuwen F. Aslam MA, et al. Among authors: van leeuwen f, van welsem t, van den brand t. EMBO Rep. 2021 Feb 3;22(2):e51184. doi: 10.15252/embr.202051184. Epub 2021 Jan 7. EMBO Rep. 2021. PMID: 33410591 Free PMC article.
1,176 results