van Mil SWC - Search Results

1

Progress and challenges of selective Farnesoid X Receptor modulation.

Massafra V, Pellicciari R, Gioiello A, van Mil SWC. Massafra V, et al. Among authors: van mil swc. Pharmacol Ther. 2018 Nov;191:162-177. doi: 10.1016/j.pharmthera.2018.06.009. Epub 2018 Jun 20. Pharmacol Ther. 2018. PMID: 29933033 Free article. Review.

2

Bile acids and their nuclear receptor FXR: Relevance for hepatobiliary and gastrointestinal disease.

Gadaleta RM, van Mil SW, Oldenburg B, Siersema PD, Klomp LW, van Erpecum KJ. Gadaleta RM, et al. Biochim Biophys Acta. 2010 Jul;1801(7):683-92. doi: 10.1016/j.bbalip.2010.04.006. Epub 2010 Apr 23. Biochim Biophys Acta. 2010. PMID: 20399894 Review.

3

Farnesoid X receptor activation inhibits inflammation and preserves the intestinal barrier in inflammatory bowel disease.

Gadaleta RM, van Erpecum KJ, Oldenburg B, Willemsen EC, Renooij W, Murzilli S, Klomp LW, Siersema PD, Schipper ME, Danese S, Penna G, Laverny G, Adorini L, Moschetta A, van Mil SW. Gadaleta RM, et al. Gut. 2011 Apr;60(4):463-72. doi: 10.1136/gut.2010.212159. Epub 2011 Jan 17. Gut. 2011. PMID: 21242261

4

Activation of bile salt nuclear receptor FXR is repressed by pro-inflammatory cytokines activating NF-κB signaling in the intestine.

Gadaleta RM, Oldenburg B, Willemsen EC, Spit M, Murzilli S, Salvatore L, Klomp LW, Siersema PD, van Erpecum KJ, van Mil SW. Gadaleta RM, et al. Biochim Biophys Acta. 2011 Aug;1812(8):851-8. doi: 10.1016/j.bbadis.2011.04.005. Epub 2011 Apr 22. Biochim Biophys Acta. 2011. PMID: 21540105 Free article.

5

Farnesoid X receptor (FXR) activation and FXR genetic variation in inflammatory bowel disease.

Nijmeijer RM, Gadaleta RM, van Mil SW, van Bodegraven AA, Crusius JB, Dijkstra G, Hommes DW, de Jong DJ, Stokkers PC, Verspaget HW, Weersma RK, van der Woude CJ, Stapelbroek JM, Schipper ME, Wijmenga C, van Erpecum KJ, Oldenburg B; Dutch Initiative on Crohn, Colitis (ICC). Nijmeijer RM, et al. PLoS One. 2011;6(8):e23745. doi: 10.1371/journal.pone.0023745. Epub 2011 Aug 22. PLoS One. 2011. PMID: 21887309 Free PMC article.

6

Pharmacological activation of the bile acid nuclear farnesoid X receptor is feasible in patients with quiescent Crohn's colitis.

van Schaik FD, Gadaleta RM, Schaap FG, van Mil SW, Siersema PD, Oldenburg B, van Erpecum KJ. van Schaik FD, et al. PLoS One. 2012;7(11):e49706. doi: 10.1371/journal.pone.0049706. Epub 2012 Nov 26. PLoS One. 2012. PMID: 23189156 Free PMC article.

7

The glucocorticoid mometasone furoate is a novel FXR ligand that decreases inflammatory but not metabolic gene expression.

Bijsmans IT, Guercini C, Ramos Pittol JM, Omta W, Milona A, Lelieveld D, Egan DA, Pellicciari R, Gioiello A, van Mil SW. Bijsmans IT, et al. Sci Rep. 2015 Sep 15;5:14086. doi: 10.1038/srep14086. Sci Rep. 2015. PMID: 26369990 Free PMC article.

8

Splenic dendritic cell involvement in FXR-mediated amelioration of DSS colitis.

Massafra V, Ijssennagger N, Plantinga M, Milona A, Ramos Pittol JM, Boes M, van Mil SW. Massafra V, et al. Biochim Biophys Acta. 2016 Feb;1862(2):166-73. doi: 10.1016/j.bbadis.2015.11.001. Epub 2015 Nov 7. Biochim Biophys Acta. 2016. PMID: 26554605 Free article.

9

Farnesoid X Receptor Activation Promotes Hepatic Amino Acid Catabolism and Ammonium Clearance in Mice.

Massafra V, Milona A, Vos HR, Ramos RJJ, Gerrits J, Willemsen ECL, Ramos Pittol JM, Ijssennagger N, Houweling M, Prinsen HCMT, Verhoeven-Duif NM, Burgering BMT, van Mil SWC. Massafra V, et al. Among authors: van mil swc. Gastroenterology. 2017 May;152(6):1462-1476.e10. doi: 10.1053/j.gastro.2017.01.014. Epub 2017 Jan 25. Gastroenterology. 2017. PMID: 28130067 Free article.

10

Quantitative liver proteomics identifies FGF19 targets that couple metabolism and proliferation.

Massafra V, Milona A, Vos HR, Burgering BM, van Mil SW. Massafra V, et al. PLoS One. 2017 Feb 8;12(2):e0171185. doi: 10.1371/journal.pone.0171185. eCollection 2017. PLoS One. 2017. PMID: 28178326 Free PMC article.

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