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Page 1
Transcription errors induce proteotoxic stress and shorten cellular lifespan.
Vermulst M, Denney AS, Lang MJ, Hung CW, Moore S, Moseley MA, Thompson JW, Madden V, Gauer J, Wolfe KJ, Summers DW, Schleit J, Sutphin GL, Haroon S, Holczbauer A, Caine J, Jorgenson J, Cyr D, Kaeberlein M, Strathern JN, Duncan MC, Erie DA. Vermulst M, et al. Among authors: sutphin gl. Nat Commun. 2015 Aug 25;6:8065. doi: 10.1038/ncomms9065. Nat Commun. 2015. PMID: 26304740 Free PMC article.
Proteasomal regulation of the hypoxic response modulates aging in C. elegans.
Mehta R, Steinkraus KA, Sutphin GL, Ramos FJ, Shamieh LS, Huh A, Davis C, Chandler-Brown D, Kaeberlein M. Mehta R, et al. Among authors: sutphin gl. Science. 2009 May 29;324(5931):1196-8. doi: 10.1126/science.1173507. Epub 2009 Apr 16. Science. 2009. PMID: 19372390 Free PMC article.
Sir2 deletion prevents lifespan extension in 32 long-lived mutants.
Delaney JR, Sutphin GL, Dulken B, Sim S, Kim JR, Robison B, Schleit J, Murakami CJ, Carr D, An EH, Choi E, Chou A, Fletcher M, Jelic M, Liu B, Lockshon D, Moller RM, Pak DN, Peng Q, Peng ZJ, Pham KM, Sage M, Solanky A, Steffen KK, Tsuchiya M, Tsuchiyama S, Johnson S, Raabe C, Suh Y, Zhou Z, Liu X, Kennedy BK, Kaeberlein M. Delaney JR, et al. Among authors: sutphin gl. Aging Cell. 2011 Dec;10(6):1089-91. doi: 10.1111/j.1474-9726.2011.00742.x. Epub 2011 Oct 3. Aging Cell. 2011. PMID: 21902802 Free PMC article.
Elevated proteasome capacity extends replicative lifespan in Saccharomyces cerevisiae.
Kruegel U, Robison B, Dange T, Kahlert G, Delaney JR, Kotireddy S, Tsuchiya M, Tsuchiyama S, Murakami CJ, Schleit J, Sutphin G, Carr D, Tar K, Dittmar G, Kaeberlein M, Kennedy BK, Schmidt M. Kruegel U, et al. PLoS Genet. 2011 Sep;7(9):e1002253. doi: 10.1371/journal.pgen.1002253. Epub 2011 Sep 8. PLoS Genet. 2011. PMID: 21931558 Free PMC article.
Absence of effects of Sir2 overexpression on lifespan in C. elegans and Drosophila.
Burnett C, Valentini S, Cabreiro F, Goss M, Somogyvári M, Piper MD, Hoddinott M, Sutphin GL, Leko V, McElwee JJ, Vazquez-Manrique RP, Orfila AM, Ackerman D, Au C, Vinti G, Riesen M, Howard K, Neri C, Bedalov A, Kaeberlein M, Soti C, Partridge L, Gems D. Burnett C, et al. Among authors: sutphin gl. Nature. 2011 Sep 21;477(7365):482-5. doi: 10.1038/nature10296. Nature. 2011. PMID: 21938067 Free PMC article.
Genome-wide analysis of yeast aging.
Sutphin GL, Olsen BA, Kennedy BK, Kaeberlein M. Sutphin GL, et al. Subcell Biochem. 2012;57:251-89. doi: 10.1007/978-94-007-2561-4_12. Subcell Biochem. 2012. PMID: 22094426 Review.
pH neutralization protects against reduction in replicative lifespan following chronological aging in yeast.
Murakami C, Delaney JR, Chou A, Carr D, Schleit J, Sutphin GL, An EH, Castanza AS, Fletcher M, Goswami S, Higgins S, Holmberg M, Hui J, Jelic M, Jeong KS, Kim JR, Klum S, Liao E, Lin MS, Lo W, Miller H, Moller R, Peng ZJ, Pollard T, Pradeep P, Pruett D, Rai D, Ros V, Schuster A, Singh M, Spector BL, Vander Wende H, Wang AM, Wasko BM, Olsen B, Kaeberlein M. Murakami C, et al. Among authors: sutphin gl. Cell Cycle. 2012 Aug 15;11(16):3087-96. doi: 10.4161/cc.21465. Epub 2012 Aug 8. Cell Cycle. 2012. PMID: 22871733 Free PMC article.
35 results