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Page 1
Combined metabolic activators improve cognitive functions in Alzheimer's disease patients: a randomised, double-blinded, placebo-controlled phase-II trial.
Yulug B, Altay O, Li X, Hanoglu L, Cankaya S, Lam S, Velioglu HA, Yang H, Coskun E, Idil E, Nogaylar R, Ozsimsek A, Bayram C, Bolat I, Oner S, Tozlu OO, Arslan ME, Hacimuftuoglu A, Yildirim S, Arif M, Shoaie S, Zhang C, Nielsen J, Turkez H, Borén J, Uhlén M, Mardinoglu A. Yulug B, et al. Among authors: tozlu oo. Transl Neurodegener. 2023 Jan 26;12(1):4. doi: 10.1186/s40035-023-00336-2. Transl Neurodegener. 2023. PMID: 36703196 Free PMC article. Clinical Trial.
Combined metabolic activators improve metabolic functions in the animal models of neurodegenerative diseases.
Turkez H, Altay O, Yildirim S, Li X, Yang H, Bayram C, Bolat I, Oner S, Tozlu OO, Arslan ME, Arif M, Yulug B, Hanoglu L, Cankaya S, Lam S, Velioglu HA, Coskun E, Idil E, Nogaylar R, Ozsimsek A, Hacimuftuoglu A, Shoaie S, Zhang C, Nielsen J, Borén J, Uhlén M, Mardinoglu A. Turkez H, et al. Among authors: tozlu oo. Life Sci. 2023 Feb 1;314:121325. doi: 10.1016/j.lfs.2022.121325. Epub 2022 Dec 26. Life Sci. 2023. Retraction in: Life Sci. 2024 Jul 15;349:122712. doi: 10.1016/j.lfs.2024.122712. PMID: 36581096 Free article. Retracted.
In Vitro and In Vivo Neuroprotective Effects of Sarcosine.
Tanas A, Tozlu ÖÖ, Gezmiş T, Hacimüftüoğlu A, Abd El-Aty AM, Ceylan O, Mardinoğlu A, Türkez H. Tanas A, et al. Among authors: tozlu oo. Biomed Res Int. 2022 Oct 15;2022:5467498. doi: 10.1155/2022/5467498. eCollection 2022. Biomed Res Int. 2022. PMID: 36281465 Free PMC article.
Combined Metabolic Activators with Different NAD+ Precursors Improve Metabolic Functions in the Animal Models of Neurodegenerative Diseases.
Altay O, Yang H, Yildirim S, Bayram C, Bolat I, Oner S, Tozlu OO, Arslan ME, Hacimuftuoglu A, Shoaie S, Zhang C, Borén J, Uhlén M, Turkez H, Mardinoglu A. Altay O, et al. Among authors: tozlu oo. Biomedicines. 2024 Apr 22;12(4):927. doi: 10.3390/biomedicines12040927. Biomedicines. 2024. PMID: 38672280 Free PMC article.
Ellagic Acid and Its Metabolites as Potent and Selective Allosteric Inhibitors of Liver Pyruvate Kinase.
Battisti UM, Gao C, Akladios F, Kim W, Yang H, Bayram C, Bolat I, Kiliclioglu M, Yuksel N, Tozlu OO, Zhang C, Sebhaoui J, Iqbal S, Shoaie S, Hacimuftuoglu A, Yildirim S, Turkez H, Uhlen M, Boren J, Mardinoglu A, Grøtli M. Battisti UM, et al. Among authors: tozlu oo. Nutrients. 2023 Jan 22;15(3):577. doi: 10.3390/nu15030577. Nutrients. 2023. PMID: 36771285 Free PMC article.
Discovery of therapeutic agents targeting PKLR for NAFLD using drug repositioning.
Zhang C, Shi M, Kim W, Arif M, Klevstig M, Li X, Yang H, Bayram C, Bolat I, Tozlu ÖÖ, Hacımuftuoglu A, Yıldırım S, Sebhaoui J, Iqbal S, Wei Y, Shi X, Nielsen J, Turkez H, Uhlen M, Boren J, Mardinoglu A. Zhang C, et al. Among authors: tozlu oo. EBioMedicine. 2022 Sep;83:104214. doi: 10.1016/j.ebiom.2022.104214. Epub 2022 Aug 18. EBioMedicine. 2022. PMID: 35988463 Free PMC article.
20 results