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AKT Hyperphosphorylation and T Cell Exhaustion in Down Syndrome.
Peeters D, Pico-Knijnenburg I, Wieringa D, Rad M, Cuperus R, Ruige M, Froeling F, Zijp GW, van der Burg M, Driessen GJA. Peeters D, et al. Front Immunol. 2022 Feb 10;13:724436. doi: 10.3389/fimmu.2022.724436. eCollection 2022. Front Immunol. 2022. PMID: 35222360 Free PMC article.
The immunophenotype and clinical characteristics of DS resemble those of Activated PI3K Delta Syndrome (APDS), in which the PI3K/AKT/mTOR pathway is overactivated. ...
The immunophenotype and clinical characteristics of DS resemble those of Activated PI3K Delta Syndrome (APDS), i …
International retrospective study of allogeneic hematopoietic cell transplantation for activated PI3K-delta syndrome.
Dimitrova D, Nademi Z, Maccari ME, Ehl S, Uzel G, Tomoda T, Okano T, Imai K, Carpenter B, Ip W, Rao K, Worth AJJ, Laberko A, Mukhina A, Néven B, Moshous D, Speckmann C, Warnatz K, Wehr C, Abolhassani H, Aghamohammadi A, Bleesing JJ, Dara J, Dvorak CC, Ghosh S, Kang HJ, Markelj G, Modi A, Bayer DK, Notarangelo LD, Schulz A, Garcia-Prat M, Soler-Palacín P, Karakükcü M, Yilmaz E, Gambineri E, Menconi M, Masmas TN, Holm M, Bonfim C, Prando C, Hughes S, Jolles S, Morris EC, Kapoor N, Koltan S, Paneesha S, Steward C, Wynn R, Duffner U, Gennery AR, Lankester AC, Slatter M, Kanakry JA. Dimitrova D, et al. J Allergy Clin Immunol. 2022 Jan;149(1):410-421.e7. doi: 10.1016/j.jaci.2021.04.036. Epub 2021 May 24. J Allergy Clin Immunol. 2022. PMID: 34033842 Free PMC article.
Update on Infections in Primary Antibody Deficiencies.
Demirdag YY, Gupta S. Demirdag YY, et al. Front Immunol. 2021 Feb 11;12:634181. doi: 10.3389/fimmu.2021.634181. eCollection 2021. Front Immunol. 2021. PMID: 33643318 Free PMC article. Review.
Autoimmune Cytopenias and Dysregulated Immunophenotype Act as Warning Signs of Inborn Errors of Immunity: Results From a Prospective Study.
Schiavo E, Martini B, Attardi E, Consonni F, Ciullini Mannurita S, Coniglio ML, Tellini M, Chiocca E, Fotzi I, Luti L, D'Alba I, Veltroni M, Favre C, Gambineri E. Schiavo E, et al. Front Immunol. 2022 Jan 4;12:790455. doi: 10.3389/fimmu.2021.790455. eCollection 2021. Front Immunol. 2022. PMID: 35058929 Free PMC article. Clinical Trial.