CD70 antibody-drug conjugate as a potential therapeutic agent for uterine leiomyosarcoma.
Nakae R, Matsuzaki S, Serada S, Matsuo K, Shiomi M, Sato K, Nagase Y, Matsuzaki S, Nakagawa S, Hiramatsu K, Okazawa A, Kimura T, Egawa-Takata T, Kobayashi E, Ueda Y, Yoshino K, Naka T, Kimura T.
Nakae R, et al.
Am J Obstet Gynecol. 2021 Feb;224(2):197.e1-197.e23. doi: 10.1016/j.ajog.2020.08.028. Epub 2020 Aug 19.
Am J Obstet Gynecol. 2021.
PMID: 32822640
BACKGROUND: Uterine leiomyosarcoma is a rare and aggressive gynecologic malignancy originating in the myometrium of the uterine corpus that tends to recur even after complete surgical excision. ...CD70 overexpression was observed in 19 of 21 (90 …
BACKGROUND: Uterine leiomyosarcoma is a rare and aggressive gynecologic malignancy originating in the myometrium of the ute …