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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
2000 1
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2011 4
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2015 4
2016 7
2017 9
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304 results

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Page 1
LRP1B: A Giant Lost in Cancer Translation.
Príncipe C, Dionísio de Sousa IJ, Prazeres H, Soares P, Lima RT. Príncipe C, et al. Pharmaceuticals (Basel). 2021 Aug 24;14(9):836. doi: 10.3390/ph14090836. Pharmaceuticals (Basel). 2021. PMID: 34577535 Free PMC article. Review.
Therefore, LRP1B expression and function in cancer remains to be fully unveiled. ...New evidence is pushing towards the increased relevance of LRP1B in cancer as a potential target or translational prognosis and response to therapy biomarker....
Therefore, LRP1B expression and function in cancer remains to be fully unveiled. ...New evidence is pushing towards the increa …
Characteristics of gastric cancer around the world.
López MJ, Carbajal J, Alfaro AL, Saravia LG, Zanabria D, Araujo JM, Quispe L, Zevallos A, Buleje JL, Cho CE, Sarmiento M, Pinto JA, Fajardo W. López MJ, et al. Crit Rev Oncol Hematol. 2023 Jan;181:103841. doi: 10.1016/j.critrevonc.2022.103841. Epub 2022 Oct 11. Crit Rev Oncol Hematol. 2023. PMID: 36240980 Review.
Gastric cancer is one of the most important malignancies in the world due to the high burden of disease and lethality. ...TP53, LRP1B, and ARID1A are consistently the most frequently altered genes in all population groups. ...
Gastric cancer is one of the most important malignancies in the world due to the high burden of disease and lethality. ...TP53, LR …
Gene methylation in gastric cancer.
Qu Y, Dang S, Hou P. Qu Y, et al. Clin Chim Acta. 2013 Sep 23;424:53-65. doi: 10.1016/j.cca.2013.05.002. Epub 2013 May 10. Clin Chim Acta. 2013. PMID: 23669186 Free article. Review.
Gastric cancer is one of the most common malignancies and remains the second leading cause of cancer-related death worldwide. ...Aberrant DNA methylation in the promoter regions of gene, which leads to inactivation of tumor suppressor and other cancer-related …
Gastric cancer is one of the most common malignancies and remains the second leading cause of cancer-related death worldwide. …
Correlation between LRP1B Mutations and Tumor Mutation Burden in Gastric Cancer.
Hu S, Zhao X, Qian F, Jin C, Hou K. Hu S, et al. Comput Math Methods Med. 2021 Sep 21;2021:1522250. doi: 10.1155/2021/1522250. eCollection 2021. Comput Math Methods Med. 2021. PMID: 34603481 Free PMC article. Retracted.
The TMB prediction capacity based on LRP1B mutation status was evaluated by ROC curves. RESULTS: LRP1B is one of the top 10 genes with high gene mutation frequency in gastric cancer. ...CONCLUSION: This study presented the relationship between TMB and LRP1 …
The TMB prediction capacity based on LRP1B mutation status was evaluated by ROC curves. RESULTS: LRP1B is one of the top 10 ge …
Clinical characteristics and prognostic analysis of SMARCA4-deficient non-small cell lung cancer.
Liang X, Gao X, Wang F, Li S, Zhou Y, Guo P, Meng Y, Lu T. Liang X, et al. Cancer Med. 2023 Jul;12(13):14171-14182. doi: 10.1002/cam4.6083. Epub 2023 May 15. Cancer Med. 2023. PMID: 37184108 Free PMC article.
PURPOSE: To improve the understanding of special types of tumors, we summarized and analyzed the clinicopathological features and prognostic factors of SMARCA4-deficient non-small cell lung cancer (SMARCA4-dNSCLC). METHODS: We selected 105 patients with SMARCA4-dNSCLC and …
PURPOSE: To improve the understanding of special types of tumors, we summarized and analyzed the clinicopathological features and prognostic …
Down-regulation of LRP1B in colon cancer promoted the growth and migration of cancer cells.
Wang Z, Sun P, Gao C, Chen J, Li J, Chen Z, Xu M, Shao J, Zhang Y, Xie J. Wang Z, et al. Exp Cell Res. 2017 Aug 1;357(1):1-8. doi: 10.1016/j.yexcr.2017.04.010. Epub 2017 Apr 11. Exp Cell Res. 2017. PMID: 28408316
In this study, it was found that LRP1B was down-regulated in colon cancer tissues and inhibited the growth, migration and metastasis of colon cancer cells. ...Taken together, our study demonstrated the suppressive roles of LRP1B in the progression of c …
In this study, it was found that LRP1B was down-regulated in colon cancer tissues and inhibited the growth, migration and meta …
Suppression of tumorigenesis in LUAD by LRP1B through regulation of the IL-6-JAK-STAT3 pathway.
Ye C, Chong W, Liu Y, Zhu X, Ren H, Xu K, Xie X, Du F, Zhang Z, Wang M, Ma T, Shang L, Li L, Chen H. Ye C, et al. Am J Cancer Res. 2023 Jul 15;13(7):2886-2905. eCollection 2023. Am J Cancer Res. 2023. PMID: 37560001 Free PMC article.
Lung adenocarcinoma (LUAD) is the most common type of lung cancer. LRP1B was initially identified as a cancer suppressor in several cancers. ...Collectively, this study highlights LRP1B as a tumor suppressor gene and reveals that LRP1B kn …
Lung adenocarcinoma (LUAD) is the most common type of lung cancer. LRP1B was initially identified as a cancer suppresso …
Potential predictive value of comutant LRP1B and FAT for immune response in non-small cell lung cancer: LRP1B and FAT comutation enhance immune response.
Hao F, Ma Q, Zhong D. Hao F, et al. Transl Oncol. 2022 Oct;24:101493. doi: 10.1016/j.tranon.2022.101493. Epub 2022 Jul 26. Transl Oncol. 2022. PMID: 35905642 Free PMC article.
RESULTS: 20 patients with co-occurring mutations in LRP1B and FAT1/2/3/4 revealed a relatively higher TMB level of 17.05 mut/Mb compared with 7.60 mut/Mb and 8.80 mut/Mb in single LRP1B and FAT mutation groups, respectively. LRP1B and FAT members showed speci …
RESULTS: 20 patients with co-occurring mutations in LRP1B and FAT1/2/3/4 revealed a relatively higher TMB level of 17.05 mut/Mb compa …
LRP1B mutations are associated with favorable outcomes to immune checkpoint inhibitors across multiple cancer types.
Brown LC, Tucker MD, Sedhom R, Schwartz EB, Zhu J, Kao C, Labriola MK, Gupta RT, Marin D, Wu Y, Gupta S, Zhang T, Harrison MR, George DJ, Alva A, Antonarakis ES, Armstrong AJ. Brown LC, et al. J Immunother Cancer. 2021 Mar;9(3):e001792. doi: 10.1136/jitc-2020-001792. J Immunother Cancer. 2021. PMID: 33653800 Free PMC article.
BACKGROUND: Low-density lipoprotein receptor-related protein 1b (encoded by LRP1B) is a putative tumor suppressor, and preliminary evidence suggests LRP1B-mutated cancers may have improved outcomes with immune checkpoint inhibitors (ICI). METHODS: We conducte …
BACKGROUND: Low-density lipoprotein receptor-related protein 1b (encoded by LRP1B) is a putative tumor suppressor, and preliminary ev …
Genome-wide profiling of HPV integration in cervical cancer identifies clustered genomic hot spots and a potential microhomology-mediated integration mechanism.
Hu Z, Zhu D, Wang W, Li W, Jia W, Zeng X, Ding W, Yu L, Wang X, Wang L, Shen H, Zhang C, Liu H, Liu X, Zhao Y, Fang X, Li S, Chen W, Tang T, Fu A, Wang Z, Chen G, Gao Q, Li S, Xi L, Wang C, Liao S, Ma X, Wu P, Li K, Wang S, Zhou J, Wang J, Xu X, Wang H, Ma D. Hu Z, et al. Nat Genet. 2015 Feb;47(2):158-63. doi: 10.1038/ng.3178. Epub 2015 Jan 12. Nat Genet. 2015. PMID: 25581428
Beyond recalculating frequencies for the previously reported frequent integration sites POU5F1B (9.7%), FHIT (8.7%), KLF12 (7.8%), KLF5 (6.8%), LRP1B (5.8%) and LEPREL1 (4.9%), we discovered new hot spots HMGA2 (7.8%), DLG2 (4.9%) and SEMA3D (4.9%). Protein expression from …
Beyond recalculating frequencies for the previously reported frequent integration sites POU5F1B (9.7%), FHIT (8.7%), KLF12 (7.8%), KLF5 (6.8 …
304 results