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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1992 1
1993 2
1995 1
1997 1
1998 2
1999 1
2000 7
2001 5
2002 2
2003 6
2004 8
2005 7
2006 6
2007 14
2008 12
2009 19
2010 24
2011 20
2012 28
2013 22
2014 31
2015 31
2016 27
2017 32
2018 20
2019 32
2020 34
2021 32
2022 25
2023 20
2024 12

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428 results

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Page 1
FGF and ROR2 receptor tyrosine kinase signaling in human skeletal development.
Stricker S, Mundlos S. Stricker S, et al. Curr Top Dev Biol. 2011;97:179-206. doi: 10.1016/B978-0-12-385975-4.00013-9. Curr Top Dev Biol. 2011. PMID: 22074606 Review.
In the past years, progress has been made in unraveling the molecular mechanisms that govern skeletal development by the use of animal models as well as by the identification of numerous mutations that cause human skeletal syndromes. Receptor tyrosine kinases …
In the past years, progress has been made in unraveling the molecular mechanisms that govern skeletal development by the use of animal model …
The dual role of the novel Wnt receptor tyrosine kinase, ROR2, in human carcinogenesis.
Ford CE, Qian Ma SS, Quadir A, Ward RL. Ford CE, et al. Int J Cancer. 2013 Aug 15;133(4):779-87. doi: 10.1002/ijc.27984. Epub 2013 Jan 10. Int J Cancer. 2013. PMID: 23233346 Free article. Review.
The Wnt signaling pathway is involved in the development and progression of many human cancers, yet attempts to target the pathway therapeutically have been disappointing to date. The recent discovery that the ROR2 receptor tyrosine kinase (RTK) is a n …
The Wnt signaling pathway is involved in the development and progression of many human cancers, yet attempts to target the pathway therapeut …
A proteogenomic portrait of lung squamous cell carcinoma.
Satpathy S, Krug K, Jean Beltran PM, Savage SR, Petralia F, Kumar-Sinha C, Dou Y, Reva B, Kane MH, Avanessian SC, Vasaikar SV, Krek A, Lei JT, Jaehnig EJ, Omelchenko T, Geffen Y, Bergstrom EJ, Stathias V, Christianson KE, Heiman DI, Cieslik MP, Cao S, Song X, Ji J, Liu W, Li K, Wen B, Li Y, Gümüş ZH, Selvan ME, Soundararajan R, Visal TH, Raso MG, Parra ER, Babur Ö, Vats P, Anand S, Schraink T, Cornwell M, Rodrigues FM, Zhu H, Mo CK, Zhang Y, da Veiga Leprevost F, Huang C, Chinnaiyan AM, Wyczalkowski MA, Omenn GS, Newton CJ, Schurer S, Ruggles KV, Fenyö D, Jewell SD, Thiagarajan M, Mesri M, Rodriguez H, Mani SA, Udeshi ND, Getz G, Suh J, Li QK, Hostetter G, Paik PK, Dhanasekaran SM, Govindan R, Ding L, Robles AI, Clauser KR, Nesvizhskii AI, Wang P, Carr SA, Zhang B, Mani DR, Gillette MA; Clinical Proteomic Tumor Analysis Consortium. Satpathy S, et al. Cell. 2021 Aug 5;184(16):4348-4371.e40. doi: 10.1016/j.cell.2021.07.016. Cell. 2021. PMID: 34358469 Free PMC article.
The ROR2 tyrosine kinase receptor regulates dendritic spine morphogenesis in hippocampal neurons.
Alfaro IE, Varela-Nallar L, Varas-Godoy M, Inestrosa NC. Alfaro IE, et al. Mol Cell Neurosci. 2015 Jul;67:22-30. doi: 10.1016/j.mcn.2015.05.002. Epub 2015 May 21. Mol Cell Neurosci. 2015. PMID: 26003414
At least three different kinds of Wnt receptors have been associated with Wnt5a signaling: seven trans-membrane Frizzled receptors and the tyrosine kinase receptors Ryk and ROR2. We report here that ROR2 is distributed in the dendrites of hippocampal n …
At least three different kinds of Wnt receptors have been associated with Wnt5a signaling: seven trans-membrane Frizzled receptors and the …
ROR-Family Receptor Tyrosine Kinases.
Stricker S, Rauschenberger V, Schambony A. Stricker S, et al. Curr Top Dev Biol. 2017;123:105-142. doi: 10.1016/bs.ctdb.2016.09.003. Epub 2016 Oct 31. Curr Top Dev Biol. 2017. PMID: 28236965 Review.
ROR-family receptor tyrosine kinases form a small subfamily of receptor tyrosine kinases (RTKs), characterized by a conserved, unique domain architecture. ...In Robinow syndrome patients and animal models, the development of multiple orga …
ROR-family receptor tyrosine kinases form a small subfamily of receptor tyrosine kinases (RTKs), c …
Upregulation of receptor tyrosine kinase-like orphan receptor 2 in idiopathic pulmonary fibrosis.
Son JH, Lee JU, Chin S, Go ES, Park JS, Shin HK, Chang HS, Park JS, Park CS. Son JH, et al. Korean J Intern Med. 2021 Jul;36(4):914-923. doi: 10.3904/kjim.2019.270. Epub 2020 Sep 21. Korean J Intern Med. 2021. PMID: 32951408 Free PMC article.
BACKGROUND/AIMS: Receptor tyrosine kinase-like orphan receptor 2 (ROR2) is a major regulator of Wnt signaling, which is involved in fibroblast dysfunction. ...ROR2 protein levels were significantly higher in GAP stage III than in GAP stag …
BACKGROUND/AIMS: Receptor tyrosine kinase-like orphan receptor 2 (ROR2) is a major regulator of Wnt signa …
Ror2 receptor requires tyrosine kinase activity to mediate Wnt5A signaling.
Mikels A, Minami Y, Nusse R. Mikels A, et al. J Biol Chem. 2009 Oct 30;284(44):30167-76. doi: 10.1074/jbc.M109.041715. Epub 2009 Aug 31. J Biol Chem. 2009. PMID: 19720827 Free PMC article.
Emerging evidence suggests that Wnt5a can inhibit Wnt/beta-catenin signaling through interaction with the receptor Ror2. The Ror2 protein belongs to the receptor tyrosine kinase superfamily and contains several recognizable structural mot …
Emerging evidence suggests that Wnt5a can inhibit Wnt/beta-catenin signaling through interaction with the receptor Ror2. The …
Extracellular vesicle-associated tyrosine kinase-like orphan receptors ROR1 and ROR2 promote breast cancer progression.
Irmer B, Efing J, Reitnauer LE, Angenendt A, Heinrichs S, Schubert A, Schulz M, Binder C, Tio J, Hansen U, Geyer C, Gerwing M, Bleckmann A, Menck K. Irmer B, et al. Cell Commun Signal. 2023 Jul 10;21(1):171. doi: 10.1186/s12964-023-01186-1. Cell Commun Signal. 2023. PMID: 37430307 Free PMC article.
To test this hypothesis, we investigated the fate of the oncogenic transmembrane Wnt tyrosine kinase-like orphan receptor 1 and 2 (ROR1, ROR2) delivered via distinct EV subpopulations to breast cancer cells and aimed to unravel their impact on tumor pr …
To test this hypothesis, we investigated the fate of the oncogenic transmembrane Wnt tyrosine kinase-like orphan receptor …
The receptor tyrosine kinase Ror2 is involved in non-canonical Wnt5a/JNK signalling pathway.
Oishi I, Suzuki H, Onishi N, Takada R, Kani S, Ohkawara B, Koshida I, Suzuki K, Yamada G, Schwabe GC, Mundlos S, Shibuya H, Takada S, Minami Y. Oishi I, et al. Genes Cells. 2003 Jul;8(7):645-54. doi: 10.1046/j.1365-2443.2003.00662.x. Genes Cells. 2003. PMID: 12839624 Free article.
BACKGROUND: Ror2 is an orphan receptor, belonging to the Ror family of receptor tyrosine kinases. ...In vitro binding assay revealed that Wnt5a binds to the CRD of Ror2. Furthermore, Ror2 associates via its CRD with rFz2, a putativ …
BACKGROUND: Ror2 is an orphan receptor, belonging to the Ror family of receptor tyrosine kinases. ...In v …
Selective modulation of Wnt-binding receptor tyrosine kinase ROR2 expression by human cytomegalovirus regulates trophoblast migration.
Huynh KT, van Zuylen WJ, Ford CE, Rawlinson WD. Huynh KT, et al. J Gen Virol. 2019 Jan;100(1):99-104. doi: 10.1099/jgv.0.001179. Epub 2018 Nov 15. J Gen Virol. 2019. PMID: 30431423
We examined CMV regulation of trophoblast migration. This virus controls expression of Wnt-binding receptor tyrosine kinase ROR2, but not alternate receptor tyrosine kinases ROR1 or RYK. ...CMV infection increased ROR2 prote …
We examined CMV regulation of trophoblast migration. This virus controls expression of Wnt-binding receptor tyrosine kinase …
428 results