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Page 1
PLA2G16 represents a switch between entry and clearance of Picornaviridae.
Staring J, von Castelmur E, Blomen VA, van den Hengel LG, Brockmann M, Baggen J, Thibaut HJ, Nieuwenhuis J, Janssen H, van Kuppeveld FJ, Perrakis A, Carette JE, Brummelkamp TR. Staring J, et al. Among authors: thibaut hj. Nature. 2017 Jan 19;541(7637):412-416. doi: 10.1038/nature21032. Epub 2017 Jan 11. Nature. 2017. PMID: 28077878
Selective serotonin reuptake inhibitor fluoxetine inhibits replication of human enteroviruses B and D by targeting viral protein 2C.
Ulferts R, van der Linden L, Thibaut HJ, Lanke KH, Leyssen P, Coutard B, De Palma AM, Canard B, Neyts J, van Kuppeveld FJ. Ulferts R, et al. Among authors: thibaut hj. Antimicrob Agents Chemother. 2013 Apr;57(4):1952-6. doi: 10.1128/AAC.02084-12. Epub 2013 Jan 18. Antimicrob Agents Chemother. 2013. PMID: 23335743 Free PMC article.
Binding of glutathione to enterovirus capsids is essential for virion morphogenesis.
Thibaut HJ, van der Linden L, Jiang P, Thys B, Canela MD, Aguado L, Rombaut B, Wimmer E, Paul A, Pérez-Pérez MJ, van Kuppeveld FJ, Neyts J. Thibaut HJ, et al. PLoS Pathog. 2014 Apr 10;10(4):e1004039. doi: 10.1371/journal.ppat.1004039. eCollection 2014 Apr. PLoS Pathog. 2014. PMID: 24722756 Free PMC article.
Itraconazole inhibits enterovirus replication by targeting the oxysterol-binding protein.
Strating JR, van der Linden L, Albulescu L, Bigay J, Arita M, Delang L, Leyssen P, van der Schaar HM, Lanke KH, Thibaut HJ, Ulferts R, Drin G, Schlinck N, Wubbolts RW, Sever N, Head SA, Liu JO, Beachy PA, De Matteis MA, Shair MD, Olkkonen VM, Neyts J, van Kuppeveld FJ. Strating JR, et al. Among authors: thibaut hj. Cell Rep. 2015 Feb 3;10(4):600-15. doi: 10.1016/j.celrep.2014.12.054. Epub 2015 Jan 29. Cell Rep. 2015. PMID: 25640182 Free PMC article.
Antiviral Activity of Broad-Spectrum and Enterovirus-Specific Inhibitors against Clinical Isolates of Enterovirus D68.
Sun L, Meijer A, Froeyen M, Zhang L, Thibaut HJ, Baggen J, George S, Vernachio J, van Kuppeveld FJ, Leyssen P, Hilgenfeld R, Neyts J, Delang L. Sun L, et al. Among authors: thibaut hj. Antimicrob Agents Chemother. 2015 Dec;59(12):7782-5. doi: 10.1128/AAC.01375-15. Epub 2015 Sep 14. Antimicrob Agents Chemother. 2015. PMID: 26369972 Free PMC article.
Enterovirus D68 receptor requirements unveiled by haploid genetics.
Baggen J, Thibaut HJ, Staring J, Jae LT, Liu Y, Guo H, Slager JJ, de Bruin JW, van Vliet AL, Blomen VA, Overduin P, Sheng J, de Haan CA, de Vries E, Meijer A, Rossmann MG, Brummelkamp TR, van Kuppeveld FJ. Baggen J, et al. Among authors: thibaut hj. Proc Natl Acad Sci U S A. 2016 Feb 2;113(5):1399-404. doi: 10.1073/pnas.1524498113. Epub 2016 Jan 19. Proc Natl Acad Sci U S A. 2016. PMID: 26787879 Free PMC article.
Role of enhanced receptor engagement in the evolution of a pandemic acute hemorrhagic conjunctivitis virus.
Baggen J, Hurdiss DL, Zocher G, Mistry N, Roberts RW, Slager JJ, Guo H, van Vliet ALW, Wahedi M, Benschop K, Duizer E, de Haan CAM, de Vries E, Casasnovas JM, de Groot RJ, Arnberg N, Stehle T, Ranson NA, Thibaut HJ, van Kuppeveld FJM. Baggen J, et al. Among authors: thibaut hj. Proc Natl Acad Sci U S A. 2018 Jan 9;115(2):397-402. doi: 10.1073/pnas.1713284115. Epub 2017 Dec 28. Proc Natl Acad Sci U S A. 2018. PMID: 29284752 Free PMC article.
The life cycle of non-polio enteroviruses and how to target it.
Baggen J, Thibaut HJ, Strating JRPM, van Kuppeveld FJM. Baggen J, et al. Among authors: thibaut hj. Nat Rev Microbiol. 2018 Jun;16(6):368-381. doi: 10.1038/s41579-018-0005-4. Nat Rev Microbiol. 2018. PMID: 29626210 Review.
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