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Objective assessment of cancer genes for drug discovery.
Patel MN, Halling-Brown MD, Tym JE, Workman P, Al-Lazikani B. Patel MN, et al. Among authors: tym je. Nat Rev Drug Discov. 2013 Jan;12(1):35-50. doi: 10.1038/nrd3913. Nat Rev Drug Discov. 2013. PMID: 23274470 Review.
canSAR: updated cancer research and drug discovery knowledgebase.
Bulusu KC, Tym JE, Coker EA, Schierz AC, Al-Lazikani B. Bulusu KC, et al. Among authors: tym je. Nucleic Acids Res. 2014 Jan;42(Database issue):D1040-7. doi: 10.1093/nar/gkt1182. Epub 2013 Dec 3. Nucleic Acids Res. 2014. PMID: 24304894 Free PMC article.
canSAR: an updated cancer research and drug discovery knowledgebase.
Tym JE, Mitsopoulos C, Coker EA, Razaz P, Schierz AC, Antolin AA, Al-Lazikani B. Tym JE, et al. Nucleic Acids Res. 2016 Jan 4;44(D1):D938-43. doi: 10.1093/nar/gkv1030. Epub 2015 Dec 15. Nucleic Acids Res. 2016. PMID: 26673713 Free PMC article.
canSAR: update to the cancer translational research and drug discovery knowledgebase.
Mitsopoulos C, Di Micco P, Fernandez EV, Dolciami D, Holt E, Mica IL, Coker EA, Tym JE, Campbell J, Che KH, Ozer B, Kannas C, Antolin AA, Workman P, Al-Lazikani B. Mitsopoulos C, et al. Among authors: tym je. Nucleic Acids Res. 2021 Jan 8;49(D1):D1074-D1082. doi: 10.1093/nar/gkaa1059. Nucleic Acids Res. 2021. PMID: 33219674 Free PMC article.
Objective, Quantitative, Data-Driven Assessment of Chemical Probes.
Antolin AA, Tym JE, Komianou A, Collins I, Workman P, Al-Lazikani B. Antolin AA, et al. Among authors: tym je. Cell Chem Biol. 2018 Feb 15;25(2):194-205.e5. doi: 10.1016/j.chembiol.2017.11.004. Epub 2017 Dec 14. Cell Chem Biol. 2018. PMID: 29249694 Free PMC article.
Leveraging Human Genetics to Guide Cancer Drug Development.
Kinnersley B, Sud A, Coker EA, Tym JE, Di Micco P, Al-Lazikani B, Houlston RS. Kinnersley B, et al. Among authors: tym je. JCO Clin Cancer Inform. 2018 Dec;2:1-11. doi: 10.1200/CCI.18.00077. JCO Clin Cancer Inform. 2018. PMID: 30652614 Free PMC article.
Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines.
Campbell J, Ryan CJ, Brough R, Bajrami I, Pemberton HN, Chong IY, Costa-Cabral S, Frankum J, Gulati A, Holme H, Miller R, Postel-Vinay S, Rafiq R, Wei W, Williamson CT, Quigley DA, Tym J, Al-Lazikani B, Fenton T, Natrajan R, Strauss SJ, Ashworth A, Lord CJ. Campbell J, et al. Cell Rep. 2016 Mar 15;14(10):2490-501. doi: 10.1016/j.celrep.2016.02.023. Epub 2016 Mar 3. Cell Rep. 2016. PMID: 26947069 Free PMC article.
canSAR: update to the cancer translational research and drug discovery knowledgebase.
di Micco P, Antolin AA, Mitsopoulos C, Villasclaras-Fernandez E, Sanfelice D, Dolciami D, Ramagiri P, Mica IL, Tym JE, Gingrich PW, Hu H, Workman P, Al-Lazikani B. di Micco P, et al. Among authors: tym je. Nucleic Acids Res. 2023 Jan 6;51(D1):D1212-D1219. doi: 10.1093/nar/gkac1004. Nucleic Acids Res. 2023. PMID: 36624665 Free PMC article.
canSAR: update to the cancer translational research and drug discovery knowledgebase.
Coker EA, Mitsopoulos C, Tym JE, Komianou A, Kannas C, Di Micco P, Villasclaras Fernandez E, Ozer B, Antolin AA, Workman P, Al-Lazikani B. Coker EA, et al. Among authors: tym je. Nucleic Acids Res. 2019 Jan 8;47(D1):D917-D922. doi: 10.1093/nar/gky1129. Nucleic Acids Res. 2019. PMID: 30496479 Free PMC article.