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5,569 results

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Lysophosphatidic acid, a simple phospholipid with myriad functions.
Yanagida K, Shimizu T. Yanagida K, et al. Pharmacol Ther. 2023 Jun;246:108421. doi: 10.1016/j.pharmthera.2023.108421. Epub 2023 Apr 18. Pharmacol Ther. 2023. PMID: 37080433 Free article. Review.
Lysophosphatidic acid (LPA) is a simple phospholipid consisting of a phosphate group, glycerol moiety, and only one hydrocarbon chain. ...
Lysophosphatidic acid (LPA) is a simple phospholipid consisting of a phosphate group, glycerol moiety, and only one hydrocarbo …
Lysophosphatidic Acid Signaling in Diabetic Nephropathy.
Lee JH, Kim D, Oh YS, Jun HS. Lee JH, et al. Int J Mol Sci. 2019 Jun 11;20(11):2850. doi: 10.3390/ijms20112850. Int J Mol Sci. 2019. PMID: 31212704 Free PMC article. Review.
Lysophosphatidic acid (LPA) is a bioactive phospholipid present in most tissues and body fluids. ...
Lysophosphatidic acid (LPA) is a bioactive phospholipid present in most tissues and body fluids. ...
Lysophosphatidic Acid Signalling in Nervous System Development and Function.
Birgbauer E. Birgbauer E. Neuromolecular Med. 2021 Mar;23(1):68-85. doi: 10.1007/s12017-020-08630-2. Epub 2020 Nov 5. Neuromolecular Med. 2021. PMID: 33151452 Review.
One class of molecules that are now coming to be recognized as essential for our understanding of the nervous system are the lysophospholipids. One of the major signaling lysophospholipids is lysophosphatidic acid, also known as LPA. LPA activates a variety of G pro …
One class of molecules that are now coming to be recognized as essential for our understanding of the nervous system are the lysophospholipi …
Lysophosphatidic acid (LPA) receptor modulators: Structural features and recent development.
Meduri B, Pujar GV, Durai Ananda Kumar T, Akshatha HS, Sethu AK, Singh M, Kanagarla A, Mathew B. Meduri B, et al. Eur J Med Chem. 2021 Oct 15;222:113574. doi: 10.1016/j.ejmech.2021.113574. Epub 2021 Jun 2. Eur J Med Chem. 2021. PMID: 34126459 Review.
Lysophosphatidic acid (LPA) activates six LPA receptors (LPAR(1-6)) and regulates various cellular activities such as cell proliferation, cytoprotection, and wound healing. ...
Lysophosphatidic acid (LPA) activates six LPA receptors (LPAR(1-6)) and regulates various cellular activities such as cell pro …
Lysophosphatidic Acid and Hematopoiesis: From Microenvironmental Effects to Intracellular Signaling.
Lin KH, Chiang JC, Ho YH, Yao CL, Lee H. Lin KH, et al. Int J Mol Sci. 2020 Mar 16;21(6):2015. doi: 10.3390/ijms21062015. Int J Mol Sci. 2020. PMID: 32188052 Free PMC article. Review.
In recent decades, breakthroughs in lineage-tracing technologies and lipidomics have revealed the existence of numerous lipid molecules in hematopoietic microenvironment. Lysophosphatidic acid (LPA), a bioactive phospholipid molecule, is one of the identified lipids …
In recent decades, breakthroughs in lineage-tracing technologies and lipidomics have revealed the existence of numerous lipid molecules in h …
Autotaxin/Lysophosphatidic Acid Axis: From Bone Biology to Bone Disorders.
Alioli C, Demesmay L, Peyruchaud O, Machuca-Gayet I. Alioli C, et al. Int J Mol Sci. 2022 Mar 22;23(7):3427. doi: 10.3390/ijms23073427. Int J Mol Sci. 2022. PMID: 35408784 Free PMC article. Review.
Lysophosphatidic acid (LPA) is a natural bioactive phospholipid with pleiotropic activities affecting multiple tissues, including bone. ...
Lysophosphatidic acid (LPA) is a natural bioactive phospholipid with pleiotropic activities affecting multiple tissues, includ …
Autotaxin-Lysophosphatidic Acid Signaling in Alzheimer's Disease.
Ramesh S, Govindarajulu M, Suppiramaniam V, Moore T, Dhanasekaran M. Ramesh S, et al. Int J Mol Sci. 2018 Jun 21;19(7):1827. doi: 10.3390/ijms19071827. Int J Mol Sci. 2018. PMID: 29933579 Free PMC article. Review.
Autotaxin (ATX) is an ecto-nucleotide pyrophosphatase/phosphodiesterase-2 enzyme that hydrolyzes extracellular lysophospholipids into the lipid mediator lysophosphatidic acid (LPA). LPA is a major bioactive lipid which acts through G protein-coupled receptors (GPCRs …
Autotaxin (ATX) is an ecto-nucleotide pyrophosphatase/phosphodiesterase-2 enzyme that hydrolyzes extracellular lysophospholipids into the li …
Emerging Roles of Lysophosphatidic Acid in Macrophages and Inflammatory Diseases.
Jiang S, Yang H, Li M. Jiang S, et al. Int J Mol Sci. 2023 Aug 7;24(15):12524. doi: 10.3390/ijms241512524. Int J Mol Sci. 2023. PMID: 37569902 Free PMC article. Review.
Lysophosphatidic acid (LPA) is a bioactive phospholipid that regulates physiological and pathological processes in numerous cell biological functions, including cell migration, apoptosis, and proliferation. ...
Lysophosphatidic acid (LPA) is a bioactive phospholipid that regulates physiological and pathological processes in numerous ce …
Role of lysophosphatidic acid and its receptors in the kidney.
Park F, Miller DD. Park F, et al. Physiol Genomics. 2017 Nov 1;49(11):659-666. doi: 10.1152/physiolgenomics.00070.2017. Epub 2017 Sep 22. Physiol Genomics. 2017. PMID: 28939644 Review.
Lysophosphatidic acid (LPA) is a bioactive phospholipid that can exert diverse biological effects in various diseased states of the kidney by activating at least six cognate G protein-coupled receptors and its complex network of heterotrimeric G proteins. ...
Lysophosphatidic acid (LPA) is a bioactive phospholipid that can exert diverse biological effects in various diseased states o …
The lysophosphatidic acid axis in fibrosis: Implications for glaucoma.
O'Regan A, O'Brien CJ, Eivers SB. O'Regan A, et al. Wound Repair Regen. 2021 Jul;29(4):613-626. doi: 10.1111/wrr.12929. Epub 2021 May 19. Wound Repair Regen. 2021. PMID: 34009724 Review.
Fibrosis in these regions leads to raised intraocular pressure and retinal ganglion cell degeneration, respectively. Lysophosphatidic acid (LPA) is a bioactive lipid mediator which acts via six G-protein coupled receptors on the cell surface to activate intracellula …
Fibrosis in these regions leads to raised intraocular pressure and retinal ganglion cell degeneration, respectively. Lysophosphatidic …
5,569 results

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