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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1937 2
1938 1
1939 2
1941 1
1942 1
1943 3
1944 2
1945 9
1946 24
1947 41
1948 36
1949 25
1950 38
1951 37
1952 49
1953 41
1954 52
1955 34
1956 36
1957 32
1958 43
1959 51
1960 55
1961 47
1962 80
1963 189
1964 209
1965 201
1966 236
1967 279
1968 283
1969 318
1970 338
1971 312
1972 322
1973 278
1974 294
1975 345
1976 319
1977 299
1978 247
1979 256
1980 287
1981 235
1982 247
1983 233
1984 267
1985 256
1986 235
1987 260
1988 228
1989 287
1990 261
1991 291
1992 297
1993 337
1994 339
1995 393
1996 410
1997 403
1998 372
1999 390
2000 394
2001 419
2002 470
2003 481
2004 482
2005 599
2006 740
2007 850
2008 1025
2009 1174
2010 1429
2011 1483
2012 1684
2013 2013
2014 1838
2015 1808
2016 1763
2017 1875
2018 1893
2019 2016
2020 2242
2021 2294
2022 2344
2023 2152
2024 1019

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41,821 results

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Page 1
The role of nicotinamide in acne treatment.
Walocko FM, Eber AE, Keri JE, Al-Harbi MA, Nouri K. Walocko FM, et al. Dermatol Ther. 2017 Sep;30(5). doi: 10.1111/dth.12481. Epub 2017 Feb 21. Dermatol Ther. 2017. PMID: 28220628 Review.
Both studies using an oral supplement containing nicotinamide resulted in a significant reduction in acne compared with baseline. ...Additional studies are needed comparing nicotinamide to other first-line acne treatments and evaluating the efficacy and side effect …
Both studies using an oral supplement containing nicotinamide resulted in a significant reduction in acne compared with baseline. ... …
What is really known about the effects of nicotinamide riboside supplementation in humans.
Damgaard MV, Treebak JT. Damgaard MV, et al. Sci Adv. 2023 Jul 21;9(29):eadi4862. doi: 10.1126/sciadv.adi4862. Epub 2023 Jul 21. Sci Adv. 2023. PMID: 37478182 Free PMC article. Review.
Nicotinamide riboside is a precursor to the important cofactor nicotinamide adenine dinucleotide and has elicited metabolic benefits in multiple preclinical studies. ...This review endeavors to summarize and critically assess the 25 currently published research arti …
Nicotinamide riboside is a precursor to the important cofactor nicotinamide adenine dinucleotide and has elicited metabolic be …
Nicotinamide: An Update and Review of Safety & Differences from Niacin.
Huber R, Wong A. Huber R, et al. Skin Therapy Lett. 2020 Nov;25(5):7-11. Skin Therapy Lett. 2020. PMID: 33196157 Free article.
Nicotinamide (or niacinamide), a form of vitamin B3 that is often confused with its precursor nicotinic acid (or niacin), is a low-cost, evidence-based oral treatment option for actinic keratosis, squamous cell carcinomas, basal cell carcinomas, and bullous pemphigo …
Nicotinamide (or niacinamide), a form of vitamin B3 that is often confused with its precursor nicotinic acid (or niacin), is a …
Nicotinamide Riboside-The Current State of Research and Therapeutic Uses.
Mehmel M, Jovanović N, Spitz U. Mehmel M, et al. Nutrients. 2020 May 31;12(6):1616. doi: 10.3390/nu12061616. Nutrients. 2020. PMID: 32486488 Free PMC article. Review.
Nicotinamide riboside (NR) has recently become one of the most studied nicotinamide adenine dinucleotide (NAD(+)) precursors, due to its numerous potential health benefits mediated via elevated NAD(+) content in the body. ...
Nicotinamide riboside (NR) has recently become one of the most studied nicotinamide adenine dinucleotide (NAD(+)) precursors, …
Possible Adverse Effects of High-Dose Nicotinamide: Mechanisms and Safety Assessment.
Hwang ES, Song SB. Hwang ES, et al. Biomolecules. 2020 Apr 29;10(5):687. doi: 10.3390/biom10050687. Biomolecules. 2020. PMID: 32365524 Free PMC article. Review.
Nicotinamide (NAM) at doses far above those recommended for vitamins is suggested to be effective against a wide spectrum of diseases and conditions, including neurological dysfunctions, depression and other psychological disorders, and inflammatory diseases. Recent increa …
Nicotinamide (NAM) at doses far above those recommended for vitamins is suggested to be effective against a wide spectrum of diseases …
The NADPARK study: A randomized phase I trial of nicotinamide riboside supplementation in Parkinson's disease.
Brakedal B, Dölle C, Riemer F, Ma Y, Nido GS, Skeie GO, Craven AR, Schwarzlmüller T, Brekke N, Diab J, Sverkeli L, Skjeie V, Varhaug K, Tysnes OB, Peng S, Haugarvoll K, Ziegler M, Grüner R, Eidelberg D, Tzoulis C. Brakedal B, et al. Cell Metab. 2022 Mar 1;34(3):396-407.e6. doi: 10.1016/j.cmet.2022.02.001. Cell Metab. 2022. PMID: 35235774 Free article. Clinical Trial.
We conducted a double-blinded phase I clinical trial to establish whether nicotinamide adenine dinucleotide (NAD) replenishment therapy, via oral intake of nicotinamide riboside (NR), is safe, augments cerebral NAD levels, and impacts cerebral metabolism in Parkinso …
We conducted a double-blinded phase I clinical trial to establish whether nicotinamide adenine dinucleotide (NAD) replenishment thera …
Nicotinamide as a Foundation for Treating Neurodegenerative Disease and Metabolic Disorders.
Maiese K. Maiese K. Curr Neurovasc Res. 2021;18(1):134-149. doi: 10.2174/1567202617999210104220334. Curr Neurovasc Res. 2021. PMID: 33397266 Free PMC article. Review.
However, nicotinamide offers cellular protection in a specific concentration range, with dosing outside of this range leading to detrimental effects. ...Nicotinamide is a highly promising target for the development of innovative strategies for neurodegenerative diso …
However, nicotinamide offers cellular protection in a specific concentration range, with dosing outside of this range leading to detr …
Nicotinamide N-methyl transferase and cancer-associated thrombosis: insights to prevention and management.
Jabbari P, Ardakany MR, Ebrahimi S, Rezaei N. Jabbari P, et al. Epigenomics. 2023 Mar;15(6):385-395. doi: 10.2217/epi-2023-0078. Epub 2023 May 22. Epigenomics. 2023. PMID: 37212051 Review.
Nicotinamide metabolism is important in carcinogenesis. Nicotinamide affects the cellular methyl pool, thus affecting DNA and histone methylation and gene expression. Cancer cells have increased expression of nicotinamide N-methyl transferase (NNMT), the key …
Nicotinamide metabolism is important in carcinogenesis. Nicotinamide affects the cellular methyl pool, thus affecting DNA and …
Oral nicotinamide for non-melanoma skin cancers: A review.
Hunt SV, Jamison A, Malhotra R. Hunt SV, et al. Eye (Lond). 2023 Apr;37(5):823-829. doi: 10.1038/s41433-022-02036-z. Epub 2022 Mar 28. Eye (Lond). 2023. PMID: 35347291 Free PMC article. Review.
There has been much interest in the role of oral nicotinamide supplementation in reducing the incidence of non-melanoma skin cancers. ...The largest RCT received criticism of the statistical analyses used, but the critics still acknowledged a likely benefit of treatment wi …
There has been much interest in the role of oral nicotinamide supplementation in reducing the incidence of non-melanoma skin cancers. …
Nicotinamide riboside is uniquely and orally bioavailable in mice and humans.
Trammell SA, Schmidt MS, Weidemann BJ, Redpath P, Jaksch F, Dellinger RW, Li Z, Abel ED, Migaud ME, Brenner C. Trammell SA, et al. Nat Commun. 2016 Oct 10;7:12948. doi: 10.1038/ncomms12948. Nat Commun. 2016. PMID: 27721479 Free PMC article.
Nicotinamide riboside (NR) is in wide use as an NAD(+) precursor vitamin. ...We report that human blood NAD(+) can rise as much as 2.7-fold with a single oral dose of NR in a pilot study of one individual, and that oral NR elevates mouse hepatic NAD(+) with distinct and su …
Nicotinamide riboside (NR) is in wide use as an NAD(+) precursor vitamin. ...We report that human blood NAD(+) can rise as much as 2. …
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