Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My NCBI Filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 1
1948 1
1952 1
1953 1
1957 1
1958 1
1959 1
1960 1
1962 1
1963 1
1964 6
1965 11
1966 4
1967 6
1968 1
1969 4
1970 7
1971 9
1972 2
1973 5
1974 2
1975 6
1976 11
1977 4
1978 3
1979 5
1980 3
1981 12
1982 8
1983 3
1984 9
1985 2
1986 8
1987 13
1988 14
1989 15
1990 18
1991 10
1992 20
1993 16
1994 12
1995 15
1996 17
1997 23
1998 21
1999 25
2000 24
2001 43
2002 59
2003 46
2004 77
2005 65
2006 83
2007 124
2008 96
2009 105
2010 176
2011 241
2012 344
2013 486
2014 432
2015 476
2016 398
2017 478
2018 412
2019 317
2020 455
2021 314
2022 224
2023 193
2024 75

Text availability

Article attribute

Article type

Publication date

Search Results

5,277 results

Results by year

Filters applied: . Clear all
Page 1
Calcium, vitamin D, vitamin K2, and magnesium supplementation and skeletal health.
Capozzi A, Scambia G, Lello S. Capozzi A, et al. Maturitas. 2020 Oct;140:55-63. doi: 10.1016/j.maturitas.2020.05.020. Epub 2020 May 30. Maturitas. 2020. PMID: 32972636 Review.
Supplementation with calcium (Ca) and/or vitamin D (vitD) is key to the management of osteoporosis. Other supplements like vitamin K2 (VitK2) and magnesium (Mg) could contribute to the maintenance of skeletal health. ...
Supplementation with calcium (Ca) and/or vitamin D (vitD) is key to the management of osteoporosis. Other supplements like vitamin …
Vitamin K2 Needs an RDI Separate from Vitamin K1.
Akbulut AC, Pavlic A, Petsophonsakul P, Halder M, Maresz K, Kramann R, Schurgers L. Akbulut AC, et al. Nutrients. 2020 Jun 21;12(6):1852. doi: 10.3390/nu12061852. Nutrients. 2020. PMID: 32575901 Free PMC article. Review.
Various isoforms of vitamin K have been identified, and vitamin K2 specifically has been highlighted for its long half-life and extrahepatic activity, whereas the dietary form vitamin K1 has a shorter half-life. ...Vitamin K2 meets all th …
Various isoforms of vitamin K have been identified, and vitamin K2 specifically has been highlighted for its long half- …
Vitamin K: Double Bonds beyond Coagulation Insights into Differences between Vitamin K1 and K2 in Health and Disease.
Halder M, Petsophonsakul P, Akbulut AC, Pavlic A, Bohan F, Anderson E, Maresz K, Kramann R, Schurgers L. Halder M, et al. Int J Mol Sci. 2019 Feb 19;20(4):896. doi: 10.3390/ijms20040896. Int J Mol Sci. 2019. PMID: 30791399 Free PMC article. Review.
Vitamin K can be present in various isoforms, distinguishable by two main structures, namely, phylloquinone (K1) and menaquinones (K2). ...Only carboxylated proteins are active and promote a health profile like hemostasis. Furthermore, vitamin K2 in th …
Vitamin K can be present in various isoforms, distinguishable by two main structures, namely, phylloquinone (K1) and menaquinones ( …
Efficacy of vitamin K2 in the prevention and treatment of postmenopausal osteoporosis: A systematic review and meta-analysis of randomized controlled trials.
Ma ML, Ma ZJ, He YL, Sun H, Yang B, Ruan BJ, Zhan WD, Li SX, Dong H, Wang YX. Ma ML, et al. Front Public Health. 2022 Aug 11;10:979649. doi: 10.3389/fpubh.2022.979649. eCollection 2022. Front Public Health. 2022. PMID: 36033779 Free PMC article.
INTRODUCTION: Vitamin K (VK) as a nutrient, is a cofactor in the carboxylation of osteocalcin (OC), which can bind with hydroxyapatite to promote bone mineralization and increase bone strength. However, some studies have been inconsistent on whether vitamin K2 …
INTRODUCTION: Vitamin K (VK) as a nutrient, is a cofactor in the carboxylation of osteocalcin (OC), which can bind with hydroxyapatit …
Vitamin K - sources, physiological role, kinetics, deficiency, detection, therapeutic use, and toxicity.
Mladěnka P, Macáková K, Kujovská Krčmová L, Javorská L, Mrštná K, Carazo A, Protti M, Remião F, Nováková L; OEMONOM researchers and collaborators. Mladěnka P, et al. Nutr Rev. 2022 Mar 10;80(4):677-698. doi: 10.1093/nutrit/nuab061. Nutr Rev. 2022. PMID: 34472618 Free PMC article. Review.
One possible explanation for this is the diversity of the biological activity of vitamin K, which is not a single compound but a general term covering natural plant and animal forms of vitamin K (K1 and K2) as well as their synthetic congeners (K3 and K4). …
One possible explanation for this is the diversity of the biological activity of vitamin K, which is not a single compound but a gene …
Vitamin K2 and D in Patients With Aortic Valve Calcification: A Randomized Double-Blinded Clinical Trial.
Diederichsen ACP, Lindholt JS, Möller S, Øvrehus KA, Auscher S, Lambrechtsen J, Hosbond SE, Alan DH, Urbonaviciene G, Becker SW, Fredgart MH, Hasific S, Folkestad L, Gerke O, Rasmussen LM, Møller JE, Mickley H, Dahl JS. Diederichsen ACP, et al. Circulation. 2022 May 3;145(18):1387-1397. doi: 10.1161/CIRCULATIONAHA.121.057008. Epub 2022 Apr 25. Circulation. 2022. PMID: 35465686 Free PMC article. Clinical Trial.
BACKGROUND: Menaquinone-7 (MK-7), also known as vitamin K2, is a cofactor for the carboxylation of proteins involved in the inhibition of arterial calcification and has been suggested to reduce the progression rate of aortic valve calcification (AVC) in patients wit …
BACKGROUND: Menaquinone-7 (MK-7), also known as vitamin K2, is a cofactor for the carboxylation of proteins involved in the in …
The Dual Role of Vitamin K2 in "Bone-Vascular Crosstalk": Opposite Effects on Bone Loss and Vascular Calcification.
Mandatori D, Pelusi L, Schiavone V, Pipino C, Di Pietro N, Pandolfi A. Mandatori D, et al. Nutrients. 2021 Apr 7;13(4):1222. doi: 10.3390/nu13041222. Nutrients. 2021. PMID: 33917175 Free PMC article. Review.
However, an increasing number of studies have reported their possible direct correlation, commonly defined as "bone-vascular crosstalk". Vitamin K2 (VitK2), a family of several natural isoforms also known as menaquinones (MK), has recently received particular attent …
However, an increasing number of studies have reported their possible direct correlation, commonly defined as "bone-vascular crosstalk". …
Vitamin K2 stimulates MC3T3-E1 osteoblast differentiation and mineralization through autophagy induction.
Li W, Zhang S, Liu J, Liu Y, Liang Q. Li W, et al. Mol Med Rep. 2019 May;19(5):3676-3684. doi: 10.3892/mmr.2019.10040. Epub 2019 Mar 15. Mol Med Rep. 2019. PMID: 30896842 Free PMC article.
Vitamin K2 likely exerts its protective effects during osteoporosis by promoting osteoblast differentiation and mineralization. ...Increasing evidence in recent years has implicated autophagy in the development of osteoporosis. The aim of the present study was to ve …
Vitamin K2 likely exerts its protective effects during osteoporosis by promoting osteoblast differentiation and mineralization …
Vitamin K2 Holds Promise for Alzheimer's Prevention and Treatment.
Popescu A, German M. Popescu A, et al. Nutrients. 2021 Jun 27;13(7):2206. doi: 10.3390/nu13072206. Nutrients. 2021. PMID: 34199021 Free PMC article. Review.
Recent studies have highlighted the importance of vitamin K2 (VK2) in human health. However, there have been no clinical studies investigating the role of VK2 in the prevention or treatment of Alzheimer's disease (AD), a debilitating disease for which currently ther …
Recent studies have highlighted the importance of vitamin K2 (VK2) in human health. However, there have been no clinical studi …
[Vitamin K2].
Ishida Y. Ishida Y. Clin Calcium. 2008 Oct;18(10):1476-82. Clin Calcium. 2008. PMID: 18830045 Review. Japanese.
Vitamin K2 has been approved for the treatment of osteoporosis in Japan since 1995. Vitamin K2 treatment in osteoporosis has been shown to inhibit the occurrence of new bone fractures and to maintain BMD. ...
Vitamin K2 has been approved for the treatment of osteoporosis in Japan since 1995. Vitamin K2 treatment in oste …
5,277 results